Korean journal of aerospace and environmental medicine (항공우주의학회지)

Aerospace Medical Association of Korea (한국항공우주의학협회)
권호 표지
DOI QR코드

DOI QR Code

The Influence of COVID-19 on Asthma and Allergic Rhinitis

COVID-19 감염증이 호흡기 알레르기 질환에 미치는 영향

  • Kim, Young Hyo (Inha Institute of Aerospace Medicine, Inha University School of Medicine)
  • 김영효 (인하대학교 우주항공의과학연구소)
  • Received : 2021.02.27
  • Accepted : 2021.03.16
  • Published : 2021.04.30
⟨ Previous Next ⟩

Abstract

As the coronavirus disease 2019 (COVID-19) pandemic continues, doctors face many difficulties in managing patients with respiratory allergies. As research continues, much new knowledge has emerged about the link between COVID-19 infection and respiratory allergies. Studies to date have shown that there is no significant increase in the risk of COVID-19 infection in patients with respiratory allergies. However, in patients undergoing treatment for moderate to severe asthma or allergic rhinitis, more severe clinical manifestations, increased hospitalization period, and increased mortality may occur, so patients need to be managed with more care. In addition to personal efforts, social consideration should be accompanied to prevent deterioration in patients' quality of life with respiratory allergies due to COVID-19. Lastly, as clinical doctors, we should treat patients with respiratory allergies to protect ourselves appropriately by actively utilizing remote medical treatment and minimizing tests that generate droplets. Also, by appropriately educating patients and continuing drug treatment, efforts should be made to ensure that patients receive the best treatment even in a pandemic situation.

Keywords

Acknowledgement

This study was supported by the Ministry of Education, Science, and Technology through the National Research Foundation of Korea (NRF2018R1A6A1A03025523).

References

  1. The Lancet Respiratory Medicine. Reflecting on World Asthma Day in the era of COVID-19. Lancet Respir Med 2020;8:423. https://doi.org/10.1016/S2213-2600(20)30184-3
  2. CDC COVID-19 Response Team. Preliminary estimates of the prevalence of selected underlying health conditions among patients with coronavirus disease 2019 - United States, February 12-March 28, 2020. MMWR Morb Mortal Wkly Rep 2020;69:382-386. https://doi.org/10.15585/mmwr.mm6913e2
  3. Li X, Xu S, Yu M, Wang K, Tao Y, Zhou Y, et al. Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan. J Allergy Clin Immunol 2020;146:110-118. https://doi.org/10.1016/j.jaci.2020.04.006
  4. Jackson DJ, Busse WW, Bacharier LB, Kattan M, O'Connor GT, Wood RA, et al. Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2. J Allergy Clin Immunol 2020;146:203-206.e3. https://doi.org/10.1016/j.jaci.2020.04.009
  5. Bradding P, Richardson M, Hinks TSC, Howarth PH, Choy DF, Arron JR, et al. ACE2, TMPRSS2, and furin gene expression in the airways of people with asthma-implications for COVID-19. J Allergy Clin Immunol 2020;146:208-211. https://doi.org/10.1016/j.jaci.2020.05.013
  6. Martinez-Lourido E, Otero A, Armisen M, Vidal C. Comment on: Bilo MB, Pravettoni V, Mauro M, Bonadonna P. Treating venom allergy during COVID-19 pandemic: management of venom allergen immunotherapy during the COVID-19 outbreak in Spain. Allergy 2021;76:951-952. https://doi.org/10.1111/all.14567
  7. Docherty AB, Harrison EM, Green CA, Hardwick H, Pius R, Norman L, et al. Features of 16,749 hospitalised UK patients with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol. 2020. https://doi.org/10.1101/2020.04.23.20076042 [Epub ahead of print]
  8. Cummings MJ, Baldwin MR, Abrams D, Jacobson SD, Meyer BJ, Balough EM, et al. Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study. Lancet 2020;395:1763-1770. https://doi.org/10.1016/S0140-6736(20)31189-2
  9. Yang JM, Koh HY, Moon SY, Yoo IK, Ha EK, You S, et al. Allergic disorders and susceptibility to and severity of COVID-19: a nationwide cohort study. J Allergy Clin Immunol 2020;146:790-798. https://doi.org/10.1016/j.jaci.2020.08.008
  10. Skevaki C, Karsonova A, Karaulov A, Xie M, Renz H. Asthma-associated risk for COVID-19 development. J Allergy Clin Immunol 2020;146:1295-1301. https://doi.org/10.1016/j.jaci.2020.09.017
  11. Schultze A, Walker AJ, MacKenna B, Morton CE, Bhaskaran K, Brown JP, et al.; OpenSAFELY Collaborative. Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids: an observational cohort study using the OpenSAFELY platform. Lancet Respir Med 2020;8:1106-1120. https://doi.org/10.1016/S2213-2600(20)30415-X
  12. Hartmann-Boyce J, Gunnell J, Drake J, Otunla A, Suklan J, Schofield E, et al. Asthma and COVID-19: review of evidence on risks and management considerations. BMJ Evid Based Med 2020. https://doi.org/10.1136/bmjebm-2020-111506
  13. Riggioni C, Comberiati P, Giovannini M, Agache I, Akdis M, Alves-Correia M, et al. A compendium answering 150 questions on COVID-19 and SARS-CoV-2. Allergy 2020;75:2503-2541. https://doi.org/10.1111/all.14449
  14. Halpin DMG, Singh D, Hadfield RM. Inhaled corticosteroids and COVID-19: a systematic review and clinical perspective. Eur Respir J 2020;55:2001009. https://doi.org/10.1183/13993003.01009-2020
  15. Morais-Almeida M, Aguiar R, Martin B, Ansotegui IJ, Ebisawa M, Arruda LK, et al. COVID-19, asthma, and biological therapies: what we need to know. World Allergy Organ J 2020;13:100126. https://doi.org/10.1016/j.waojou.2020.100126
  16. Brindisi G, De Vittori V, De Castro G, Duse M, Zicari AM. Pills to think about in allergic rhinitis children during COVID-19 era. Acta Paediatr 2020;109:2149-2150. https://doi.org/10.1111/apa.15462
  17. The Korean Academy of Asthma, Allergy and Clinical Immunology. World Allergy Week 2020 [Internet]. Seoul: The Korean Academy of Asthma, Allergy and Clinical Immunology; 2020 [cited 2021 Feb 27]. Available from: https://www.allergy.or.kr/board/view.html?num=2071&start=30&code=notice&comm=&key=&keyword=