Journal of the Korea Convergence Society (한국융합학회논문지)

Korea Convergence Society (한국융합학회)
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The Urine Cotinine level and Periodontal Disease among Environmental Tobacco Smoke Exposure on Convergence study

간접흡연자의 요코티닌과 치주질환의 관련성에 관한 융합연구

  • Kim, Song Sook (Department of Dental Hygiene, Suwon Science College)
  • 김송숙 (수원과학대학교 치위생과)
  • Received : 2018.09.27
  • Accepted : 2018.12.20
  • Published : 2018.12.28
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Abstract

The aim of this study was to evaluate the association between the level urine cotinine and periodontal diseases in Korea adults. The date from the 2014, 2015 Korean National Health and Nutrition Survey were used, and 5,146 subjects over 30 years were included in the analysis. Periodontal disease was assessed using the Community Periodontal Index. Binary logistic regression model was used to estimate the odds ratio with 95% confidence intervals. There was a 2.08-fold (95% CI; 1.73-2.05) increased in the odds of periodontal disease for those with any ETS exposure compared with those with non-smokers following adjustment for sex, age, education, and income. The level of urine cotinine also showed a dose-dependent increase in extent of periodontal disease. Among persons in the Korea who had never used tobacco, those exposed to ETS were more likely to have periodontal disease than were those not exposed to ETS. In the future, voluntary compliance of smokers to measures to reduce ETS exposure should be encouraged.

본 연구의 목적은 30세이상 성인을 대상으로 간접흡연노출과 치주질환과의 관련성을 파악하고자 하였다. 연구자료는 2014년, 2015년 국민건강영양조사 자료를 이용하였으며, 5,146명을 최종분석대상자로 선정하였다. 치주질환은 지역사회 치주지수로 파악하였다. 이분형 로지스틱회귀분석을 이용하였으며, 95% 신뢰구간을 산출하였다. 본 연구결과 성별, 연령, 교육수준, 그리고 수입을 보정한 경우에서 요코티닌 수준이 50ng/mL미만에 비해 550ng/mL이상인 경우에서 치주질환 위험이 2.08배(95% CI=1.73-2.50) 높게 나타났다. 요코티닌 수준과 치주질환 위험 증가에 대한 용량-반응관계가 나타났다. 본 연구결과 간접흡연자에서 요코티닌 수준이 증가할수록 치주질환 위험이 증가하는 것으로 나타났다. 향후 간접흡연에 대한 노출을 감소시키기 위해 흡연자의 자발적인 금연참여를 권장하여야 할 것이다.

Keywords

Table 1. Characteristics of study subjects

OHHGBW_2018_v9n12_295_t0001.png 이미지

Table 2. The ORs of periodontal disease according level of urine cotinine among ETC exposure

OHHGBW_2018_v9n12_295_t0002.png 이미지

References

  1. A. Schulze, M. Busse. (2016). Gender differences in periodontal status and oral hygiene of non-diabetic and type 2 diabetic patients. The open dentistry journal, 10, 287-297. DOI : 10.2174/1874210601610010287
  2. J. H. Kim. (2018). The Association between Obesity and Peiodontal Diasease on Convergence Study. Journal of the Korea Convergence Scociety, 9(8), 71-76. DOI : 10.15207/JKCS.2018.9.8.071
  3. J. H. Kim. (2016). Association between cigarette smoking status and eriodontal disease in adults: results from the 2012 Korea ational health and nutrition examination survey. Journal of Korean Academy of Oral Health, 40(2), 133-139. DOI : 10.11149/jkaoh.2016.40.2.133
  4. A. E. Sanders, G. D. Slade, J. D. Beck,, H. Agustsdottir. (2011). Secondhand smoke and periodontal disease: atherosclerosis risk in communities study. American journal of public health, 101(S1), S339-S346. DOI : 10.2174/1874210601610010287
  5. G, B. Rheu, S. Ji, J. J. Ryu, J. B. Lee, C. Shin, J. Y. Lee. (2011). Risk assessment for clinical attachment loss of periodontal tissue in Korean adults. The journal of advanced prosthodontics, 3(1), 25-32. DOI : 10.4047/jap.2011.3.1.25
  6. US Department of Health and Human Services. (2006). The health consequences of involuntary exposure to tobacco smoke: a report of the Surgeon General, Atlanta : USA Publishing.
  7. S. A. Glantz, W. W. Parmley. (1991). Passive smoking and heart disease. Epidemiology, physiology, and biochemistry. Circulation, 83(1), 1-12. https://doi.org/10.1161/01.CIR.83.1.1
  8. S. J. Arbes, H. Agustsdottir, G. D. Slade. (2001). Environmental tobacco smoke and periodontal disease in the United States. American journal of public health, 91(2), 253-257. DOI : 10.2105/AJPH.91.2.253
  9. Y. Numabe, T. Ogawa, H. Kamoi, K. Kiyonobu, S. Sato, K. Kamoil. (1998). Phagocytic function of salivary PMN after smoking or secondary smoking. Annals of periodontology, 3(1), 102-107. DOI : 10.1902/annals.1998.3.1.102
  10. Y. Gonzalez, A. De Nardin, S. Grossi, E. Machtei, R. Genco, E. De Nardin. (1996). Serum cotinine levels, smoking, and periodontal attachment loss. Journal of dental research, 75(2), 796-802. DOI : 10.1177/00220345960750021001
  11. M. J. Jarvis, H. Tunstall-Pedoe, C. Feyerabend, C. Vesey, Y. Saloojee. (1987). Comparison of tests used to distinguish smokers from nonsmokers. American journal of public health, 77(11), 1435-1438. DOI : 10.2105/AJPH.77.11.1435
  12. D. L. Patrick, A. Cheadle, D. C. Thompson, P. Diehr, T. Koepsell, S. Kinne. (1994). The validity of self-reported smoking: a review and meta-analysis. American journal of public health, 84(7), 1086-1093. DOI : 10.2105/AJPH.84.7.1086
  13. N. L. Benowitz. (1996). Cotinine as a biomarker of environmental tobacco smoke exposure. Epidemiologic reviews, 18(2), 188-204. https://doi.org/10.1093/oxfordjournals.epirev.a017925
  14. Y. Yamamoto, N. Nishida, M. Tanaka, N. Hayashi, R. Matsuse, K. Nakayama, (2005). Association between passive and active smoking evaluated by salivary cotinine and periodontitis. Journal of clinical periodontology, 32(10), 1041-1046. DOI : 10.1111/j.1600-051X.2005.00819.x
  15. World Health Organization. (1995). Oral Health Surveys: Basic Methods. World Health Organization. [internet], [cited 2018 April 10], Available From: http://apps.who.int/iris/bitstream/handle/10665/97035/9789241548649_eng.pdf;jsessionid=A315AD83D978E38F13B7F95ECF034049?sequence=1.pdf.
  16. W. Zielinska-Danch, W. Wardas, A. Sobczak, I. Szoltysek-Boldys. (2007). Estimation of urinary cotinine cut-off points distinguishing non-smokers, passive and active smokers. Biomarkers, 12(5), 484-496. DOI : 10.1080/13547500701421341
  17. E. O. Erdemir, I. S. Sonmez, A. A. Oba, J. Bergstrom, O. Caglayan. (2010). Periodontal health in children exposed to passive smoking. Journal of clinical periodontology, 37(2), 160-164. DOI : 10.1111/j.1600-051X.2009.01510.x
  18. K. Tanaka, Y. Miyake, T. Hanioka, M. Arakawa. (2013). Active and passive smoking and prevalence of periodontal disease in young Japanese women. Journal of periodontal research, 48(5), 600-605. DOI : 10.1111/jre.12044
  19. G. E. Salvi, H. P. Lawrence, S. Offenbacher, J. D. Beck. (1997). Influence of risk factors on the pathogenesis of periodontitis. Periodontology 2000, 14(1), 173-201. DOI : 10.1111/j.1600-0757.1997.tb00197.x
  20. C. I. Vardavas, D. B. Panagiotakos. (2009). The causal relationship between passive smoking and inflammation on the development of cardiovascular disease: a review of the evidence. Inflammation & Allergy-Drug Targets, 8(5), 328-333. DOI : 10.2174/187152809790031243