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Antioxidant Effects of Herbal Wine containing Acanthopanax sessiliflorus, Lycium chinense, Schizandra chinensis, Cuscutae semen, Rubus coreanum and Plantaginis semen

오가피, 구기자, 오미자, 토사자, 복분자 및 차전자를 첨가한 한방 약술의 항산화 효과

  • Oh, Sung-Cheon (Dept. of Pharmaceutical Quality Control, Daewon University College)
  • 오성천 (대원대학교 제약품질관리과)
  • Received : 2016.12.08
  • Accepted : 2016.12.23
  • Published : 2016.12.30

Abstract

In this study, the electron donating ability(EDA) and total polyphenol content of herbal wine were examined. The herbal wine was obtained from extract concentration to evaluate its functional properties. The herbal wine were screened for their potential antioxidant activities using test such as electron donating ability(EDA) and total polyphenol content. The electron donating ability(EDA) were $21.81{\pm}0.56$ in herbal wine 15% and $40.45{\pm}1.60$ in herbal wine 35%. As the extract concentration was increased the electron donating ability(EDA) were significantly increased(p<0.05). The total polyphenol contents were measures $113.89{\pm}1.79{\mu}g\;GAE/m{\ell}$ in herbal wine 15%, $274.24{\pm}0.71{\mu}g\;GAE/m{\ell}$ in herbal wine 35%. As the extract concentration was increased the total polyphenol contents were significantly increased(p<0.05). Also, the total polyphenol contents were measures $61.75{\mu}g\;GAE/m{\ell}$ in herbal wine, the higher.

본 연구는 추출물 농도에 따른 생리활성물질의 용출량을 측정하기 위해 전자공여능과 총 폴리페놀 함량을 측정한 결과이다. 전자공여능은 추출물의 첨가 농도가 15%인 경우는 21.81%로 나타났고, 35% 농도에서 40.45%로 가장 높았다. 한약재의 첨가 농도가 증가함에 따라 전자공여능은 유의적으로 증가하였다(p<0.05). 가장 높은 35% 첨가 농도에서의 40.45% 공여능은 이보다 더 낮았으므로 전자공여능은 미약한 것으로 생각된다. 총 폴리페놀함량은 한방약술 15%에서는 $113.89{\pm}1.79{\mu}g\;GAE/m{\ell}$로 나타났고, 한방약술 35% 에서는 $274.24{\pm}0.71{\mu}g\;GAE/m{\ell}$로 나타나서 첨가물의 농도 증가에 따라 총 폴리페놀의 함량도 유의적으로 증가하였다(p<0.05). 추출물 농도가 30%에서 총 폴리페놀 함량의 증가 폭이 $61.75{\mu}g\;GAE/m{\ell}$로 가장 높았다.

Keywords

References

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  1. 추출농도에 따른 오미자 및 구기자를 첨가한 한방약술의 품질특성 vol.36, pp.1, 2019, https://doi.org/10.12925/jkocs.2019.36.1.341