Journal of Korean Society of Occupational and Environmental Hygiene (한국산업보건학회지)

Korean Industrial Hygiene Association (한국산업보건학회)
권호 표지

Immunological Assessment of Respiratory Allergy Status for the Swine Farm Workers in Gyeonggi Province of Korea

경기 일부지역 양돈 축산인들의 호흡기 알레르기 관련 면역학적 지표 분석

  • Kim, Ji Youn (Catholic University of Daegu, College of Natural Sciences Dept. Occupational Health) ;
  • Kim, Kwang Ho (Biotoxtech Co., Ltd.) ;
  • Hwang, So Ryeon (Catholic University of Daegu, College of Natural Sciences Dept. Occupational Health) ;
  • Yeo, Kyeong Uk (Catholic University of Daegu, College of Natural Sciences Dept. Occupational Health) ;
  • Kim, Hyoung Ah (Catholic University of Korea, College of Medicine Dept. Preventive Medicine) ;
  • Heo, Yong (Catholic University of Daegu, College of Natural Sciences Dept. Occupational Health)
  • 김지연 (대구가톨릭대학교 자연대학 산업보건학과) ;
  • 김광호 ((주)바이오톡스텍 일반독성부) ;
  • 황소련 (대구가톨릭대학교 자연대학 산업보건학과) ;
  • 여경욱 (대구가톨릭대학교 자연대학 산업보건학과) ;
  • 김형아 (가톨릭대학교 의과대학 예방의학교실) ;
  • 허용 (대구가톨릭대학교 자연대학 산업보건학과)
  • Published : 2012.12.31
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Abstract

Objectives: Animal husbandry workers could be exposed to various work hazards including toxic gases, chemicals such as pesticides or organic dust. Immunological evaluation focusing on respiratory allergic hypersensitivity occurrence was under-taken for swine farm workers as a part of the study on immunologic status of dairy barn, swine confinement, and poultry farm workers. Materials and Methods: Peripheral bloods were collected from 25 workers at the year of 2001 and 12 workers at the year of 2012 from swine farms located at Gyeonggi province, Korea. Seven adults not involved with animal husbandry were recruited at the year of 2001 from the same residential area as the swine farm workers'. Level of plasma IgE and 20 respiratory allergen-specific IgE were evaluated using commercially available ELISA kit. Results: Plasma IgE level was approximately five-fold higher in the swine farm workers regardless of the sampling year than the control subjects. Plant allergens from outdoor environments such as golden rod, pigweed, Russian thistle, or ragweed were the major allergens with positive reaction(allergen specific IgE${\geq}$0.7 IU/mL) for the swine farm workers at 2001 year. Meanwhile, house dust mite(Dermatophagoides farinae, D. pteronyssinus) and cockroach, typical indoor allergens in Korea, were the major respiratory allergens for the swine farm workers at 2012 year. Conclusions: Overall, even though our results are primitive, the results suggest that immunological function of swine farm workers could be modulated toward type-2 reactivity.

Keywords

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