Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
권호 표지

Effects of Neuromuscular Electrical Stimulation on Distracted Boneafter Mandibular Distraction Osteogenesis in Canine Model

성견의 하악골 골신장술 후 골 형성에 대한 신경근육의 전기적 자극의 효과

  • Son, Jang-Ho (Department of Oral & Maxillofacial Surgery, College of Medicine, University of Ulsan) ;
  • Park, Bong-Wook (Department of Oral & Maxillofacial Surgery, College of Medicine, Gyeongsang National University) ;
  • Byun, June-Ho (Department of Oral & Maxillofacial Surgery, College of Medicine, Gyeongsang National University) ;
  • Cho, Yeong-Cheol (Department of Oral & Maxillofacial Surgery, College of Medicine, University of Ulsan) ;
  • Sung, Iel-Yong (Department of Oral & Maxillofacial Surgery, College of Medicine, University of Ulsan)
  • 손장호 (울산대학교 의과대학 구강악안면외과학교실) ;
  • 박봉욱 (경상대학교 의과대학 구강악안면외과학교실) ;
  • 변준호 (경상대학교 의과대학 구강악안면외과학교실) ;
  • 조영철 (울산대학교 의과대학 구강악안면외과학교실) ;
  • 성일용 (울산대학교 의과대학 구강악안면외과학교실)
  • Received : 2010.06.18
  • Accepted : 2011.01.04
  • Published : 2011.03.31
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Abstract

Purpose: This study was designed to examine whether the use of neuromuscular electrical stimulation (NMES) after mandibular distraction osteogenesis accelerated bone formation and consolidation. Methods: Eight adult dogs underwent mandibular left body osteotomy. After a 3 day latency period, a distraction rod device was activated at a rate of 1.0 mm once per day for 10 days. After the completion of mandibular lengthening, NMES group was treated twice daily with 2 hours of NMES for 14, and 28 days, while non-NMES group did not receive NMES. The distracted segment was evaluated radiolgraphically histologically and than immunohistochemically for osteopontin (OPN) to evaluate new bone formation and consolidation. Results: Radiography, did not demonstrate significantly different images between the group and the NMES group. Histological examination however, showed that the new bone formation 14 and 28 days after distraction was better in the NMES group when compared to non-NMES group. Immunohistochemical analysis demonstrated that the staining intensity of OPN increased more in the NMES group than in non-NMES group during early consolidation. Conclusion: The results of this study demonstrated that the use of NMES can promote bone formation and consolidation.

Keywords

References

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