Development of Hand-held OCT probe for Ophthalmic Imaging

안구 영상을 위한 OCT용 손잡이 형 프로브의 개발

  • Cho, Nam-Hyun (Graduate School of Electrical Engineering and Computer Science Kyoungpook National University) ;
  • Jung, Woong-Gyu (Beckman Institute for Advanced Science and Technology, University of Illinois at Ulbana-Champaign) ;
  • Jung, Un-Sang (Graduate School of Electrical Engineering and Computer Science Kyoungpook National University) ;
  • Sephen, A.Boppart (Beckman Institute for Advanced Science and Technology, University of Illinois at Ulbana-Champaign) ;
  • Shim, Jae-Hoon (Graduate School of Electrical Engineering and Computer Science Kyoungpook National University) ;
  • Kim, Jee-Hyun (Graduate School of Electrical Engineering and Computer Science Kyoungpook National University)
  • 조남현 (경북대학교 전자전기컴퓨터대학원) ;
  • 정웅규 ;
  • 정운상 (경북대학교 전자전기컴퓨터대학원) ;
  • ;
  • 심재훈 (경북대학교 전자전기컴퓨터대학원) ;
  • 김지현 (경북대학교 전자전기컴퓨터대학원)
  • Received : 2010.06.21
  • Accepted : 2010.11.29
  • Published : 2011.01.25

Abstract

We have developed a hand-held probe for an ophthalmic OCT system. The hand-held probe for imaging was designed to be compact and portable. The cornea and retinal images were acquired by replacing the objective lens at the front of the probe. To verify the performance of the hand-held OCT probe, we acquired two dimensional OCT image of the rat eye in vivo and reconstructed three dimensional rat eye rendering images. In vivo 3D OCT images were showed distinct structural information in the posterior and anterior chamber with minimal motion artifacts. Thereby, OCT imaging speed is suitable for an dynamic in vivo experiment.

본 연구에서는 안구 영상을 위한 OCT용 손잡이 형 프로브를 개발하였다. 프로브는 휴대하기 간편한 손잡이 형태로 구현하였으며, 어댑터의 대물렌즈를 교체함으로써 각막(cornea)과 망막(retina) 모두 영상화 할 수 있도록 설계 하였다. 시스템의 성능검증을 위해 in vivo로 실험용 쥐의 눈 영상을 2D로 획득하였으며, 획득한 영상을 3D 영상으로 재구성하였다. 3D 영상은 쥐의 미세한 부분의 구조를 잘 나타내었으며, 움직임에 의한 흔들림 현상(Motion artifact)이 나타나지 않았으므로 개발된 OCT시스템의 이미지 디스플레이 속도는 생체 내 실험 (in vivo)에 적합함을 알 수 있었다.

Keywords

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