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Comparison of elective inguinal node irradiation techniques in anal cancer

  • Cha, Ji-Hye (Department of Radiation Oncology, Yonsei University College of Medicine) ;
  • Seong, Jin-Sil (Department of Radiation Oncology, Yonsei University College of Medicine) ;
  • Keum, Ki-Chang (Department of Radiation Oncology, Yonsei University College of Medicine) ;
  • Lee, Chang-Geol (Department of Radiation Oncology, Yonsei University College of Medicine) ;
  • Koom, Woong-Sub (Department of Radiation Oncology, Yonsei University College of Medicine)
  • 투고 : 2011.09.16
  • 심사 : 2011.10.07
  • 발행 : 2011.12.31

초록

Purpose: To compare photon thunderbird with deep match (technique 1) with 3-field technique with electron inguinal boost (technique 2) in acute skin toxicity, toxicity-related treatment breaks and patterns of failure in elective inguinal radiation therapy (RT) for curative chemoradiation in anal cancer. Materials and Methods: Seventeen patients treated between January 2008 and September 2010 without evidence of inguinal and distant metastasis were retrospectively reviewed. In 9 patients with technique 1, dose to inguinal and whole pelvis area was 41.4 to 45 Gy and total dose was 59.4 Gy. In 8 patients with technique 2, doses to inguinal, whole pelvis, gross tumor were 36 to 41.4 Gy, 36 to 41.4 Gy, and 45 to 54 Gy, respectively. The median follow-up period was 27.6 and 14.8 months in group technique 1 and 2, respectively. Results: The incidences of grade 3 radiation dermatitis were 56% (5 patients) and 50% (4 patients), dose ranges grade 3 dermatitis appeared were 41.4 to 50.4 Gy and 45 to 54 Gy in group technique 1 and 2, respectively (p = 0.819). The areas affected by grade 3 dermatitis in 2 groups were as follow: perianal and perineal areas in 40% and 25%, perianal and inguinal areas in 0% and 50%, and perianal area only in 60% and 25%, respectively (p = 0.196). No inguinal failure has been observed. Conclusion: Photon thunderbird with deep match technique and 3-field technique with electron inguinal boost showed similar incidence of radiation dermatitis. However, photon thunderbird with deep match seems to increase the possibility of severe perineal dermatitis.

키워드

참고문헌

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피인용 문헌

  1. Indigenous groin board immobilization reduces planning target volume margins in groin radiotherapy vol.46, pp.2, 2011, https://doi.org/10.4103/jmp.jmp_120_20