Primary Retrobulbar Meningioma in a Dog

개에서 발생한 원발성 안구 후방 수막종 1례

  • Ahn, Jae-Sang (College of Veterinary Medicine, Seoul National University) ;
  • Jeong, Man-Bok (College of Veterinary Medicine, Seoul National University) ;
  • Kim, Won-Tae (College of Veterinary Medicine, Seoul National University) ;
  • Kim, Se-Eun (College of Veterinary Medicine, Seoul National University) ;
  • Park, Young-Woo (College of Veterinary Medicine, Seoul National University) ;
  • Kim, Tae-Hyun (College of Veterinary Medicine, Seoul National University) ;
  • Ahn, Jeong-Taek (College of Veterinary Medicine, Seoul National University) ;
  • Ha, Jeong-Im (College of Veterinary Medicine, Seoul National University) ;
  • Kim, Dae-Yong (College of Veterinary Medicine, Seoul National University) ;
  • Choi, Min-Cheol (College of Veterinary Medicine, Seoul National University) ;
  • Yoon, Jung-Hee (College of Veterinary Medicine, Seoul National University) ;
  • Seo, Kang-Moon (College of Veterinary Medicine, Seoul National University)
  • Published : 2010.02.28

Abstract

A 13-year-old neutered female Maltese was referred to Veterinary Medical Teaching Hospital of Seoul National University with 8-month-history of gradually enlarging retrobulbar mass in the right eye. On the ophthalmic examinations, exophthalmos, exposure keratitis, and cataract were observed, and menace response was absent in the eye. The fellow eye was normal except for nuclear sclerosis. On the ocular ultrasonographic evaluation, a mass was identified in retrobulbar and periocular region in the right eye. Exenteration was performed in order to remove the mass. Histopathologic evaluation revealed that most part of the mass was composed of epithelial-like neoplastic cells. Invasion into adipose cells and osseous metaplasia around the mass were also confirmed. Based on the radiologic and histopathologic examination, the mass in the right eye was diagnosed as primary retrobulbar meningioma. Eleven months after the surgery, recurrence was not observed.

Keywords

References

  1. 안세준, 석준수, 안지영, 임수지, 정성목, 박성준, 조성환, 최호정, 이영원. 개에서 발생한 안와 수막종 1례. 한국임상 수의학회지 2009; 26: 290-297.
  2. 지현철, 이재연, 정기현, 김명철, 조성환, 이영원, 최호정, 박성준, 정성목. 푸들견에서의 두개강외 수막종 증례. 한국 임상수의학회지 2006; 23: 161-161.
  3. Barnhart KF, Wojcieszyn J, Storts RW. Immunohistochemical staining patterns of canine meningiomas and correlation with published immunophenotypes. Vet Pathol 2002; 39: 311-321. https://doi.org/10.1354/vp.39-3-311
  4. Hendrix DV, Gelatt KN. Diagnosis, treatment and outcome of orbital neoplasia in dogs: a retrospective study of 44 cases. J Small Anim Pract 2000; 41: 105-108. https://doi.org/10.1111/j.1748-5827.2000.tb03175.x
  5. Larocca RD. Unilateral external and internal ophthalmoplegia caused by intracranial meningioma in a dog. Vet Ophthalmol 2000; 3: 3-9. https://doi.org/10.1046/j.1463-5224.2000.00089.x
  6. Mauldin EA, Deehr AJ, Hertzke D, Dubielzig RR. Canine orbital meningiomas: A review of 22 cases. Vet Ophthalmol 2000; 1: 11-16.
  7. McDonnell JJ, Kalbko K, Keating JH, Sato AF, Faissler D. Multiple meningiomas in three dogs. J Am Anim Hosp Assoc 2007; 43: 201-208.
  8. Montoliu P, Anor S, Vidal E, Pumarola M. Histological and immunohistochemical study of 30 cases of canine meningioma. J Comp Pathol 2006; 135: 200-207. https://doi.org/10.1016/j.jcpa.2006.06.006
  9. Patnaik AK, Kay WJ, Hurvitz AI. Intracranial meningioma: A comparative pathologic study of 28 dogs. Vet Pathol 1986; 4: 369-373.
  10. Perez V, Vidal E, Gonzalez N, Benavides J, Ferreras MC, Villagrasa M, Pumarola M. Orbital meningioma with a granular cell component in a dog, with extracranial metastasis. J Comp Pathol 2005; 133: 212-217. https://doi.org/10.1016/j.jcpa.2005.02.003
  11. Petersen SA, Sturges BK, Dickinson PJ, Pollard RE, Kass PH, Kent M, Vernau KM, LeCouteur RA, Higgins RJ, Canine intraspinal meningiomas: Imaging features, histopathologic classification, and long-term outcome in 34 dogs. J Vet Intern Med 2008; 22: 946-953. https://doi.org/10.1111/j.1939-1676.2008.0106.x
  12. Ribas JL, Carpenter JL, Mena H, Schulman FY, Lee K. Central nervous system meningioma in the dog: a review of 50 cases. J Neuropathol Exp Neurol 1991; 50: 373.
  13. Schmidt P, Geyer C, Hafner A, Bise K, Hermanns W. Malignant meningioma with lung metastases in a Boxer. Tierarztl Prax 1991; 19: 315-319.
  14. Schulman FY, Ribas JL, Carpenter JL, Sisson AF, LeCouteur RA. Intracranial meningioma with pulmonary metastasis in three dogs. Vet Pathol 1992; 29: 196-202. https://doi.org/10.1177/030098589202900302
  15. Webb AA, Cullen CL, Rose P, Eisenbart D, Gabor L, Martinson S. Intracranial meningioma causing internal ophthalmoparesis in a dog. Vet Ophthalmol 2005; 6: 421-425.