Survey of Heavy Metal Contents and Intake Rates After Decoction in Herbal Medicines Classified by Parts

한약재의 약용부위별 중금속 함량 및 탕 액에서의 이행률 조사

  • Jung, Sam-Ju (Seoul Metropolitan Government Research Institute of Public Health and Environment, Department of Food Science and Technology) ;
  • Kang, Sung-Tae (Seoul National University of Technology) ;
  • Han, Chang-Ho (Seoul Metropolitan Government Research Institute of Public Health and Environment, Department of Food Science and Technology) ;
  • Kim, Su-Jin (Seoul Metropolitan Government Research Institute of Public Health and Environment, Department of Food Science and Technology) ;
  • Ko, Suk-Kyung (Seoul Metropolitan Government Research Institute of Public Health and Environment, Department of Food Science and Technology) ;
  • Kim, Yun-Hee (Seoul Metropolitan Government Research Institute of Public Health and Environment, Department of Food Science and Technology) ;
  • Kim, Yoo-Kyung (Seoul Metropolitan Government Research Institute of Public Health and Environment, Department of Food Science and Technology) ;
  • Kim, Bog-Soon (Seoul Metropolitan Government Research Institute of Public Health and Environment, Department of Food Science and Technology) ;
  • Choi, Byung-Hyun (Seoul Metropolitan Government Research Institute of Public Health and Environment, Department of Food Science and Technology)
  • Received : 2010.08.06
  • Accepted : 2010.11.30
  • Published : 2010.12.31

Abstract

The study was conducted to estimate the contents of heavy metal in commercial herbal medicines (1047 samples of 132 species) which were collected from markets in Seoul and to analyze the contents of heavy metals of herbal medicines by classifying them by parts. The samples were digested using microwave method. The contents of heavy metal (Pb, Cd, and As) and Hg were determined using Inductively coupled plasma-Mass spectrometer (ICP/MS). And the contents of Hg were obtained by Mercury analyzer. The average values of heavy metal in herbal medicines were as follows [mean (minimum-maximum), mg/kg]; Pb 0.870 (ND-69.200), As 0.148 (ND-2.965), Cd 0.092 (ND-2.010), and Hg 0.007 (ND-0.B7). And the average values of heavy metal by parts in herbal medicines were as follows [mean (minimum-maximum), mg/kg]; Ramulus 2.046 (0.065-4.474), Herba 1.886 (0.048-10.404), Flos 1.874 (0.052-5.393), Cortex 1.377 (0.011-4.837), Radix 1.165 (0.012-70.111), Rhizoma 1.116 (0.016-5.490, Fructus 0.838 (0.017-4.527), Perithecium 0.729 (0.013-4.953), Semen 0.646 (0.006-4.416). The average values of heavy metal of imported herbal medicines except Radix were higher than domestic ones. By decoction of herbal medicines exceeding the tolerances, average intake rates of Pb, As, Cd and Hg were obtained as 6.1%, 40.3%, 4.7%, and 2.2%, respectively.

본 연구에서는 국내에서 유통되는 한약재 132품목 1047건을 대상으로 하여 납, 비소, 카드뮴, 수은의 함량을 측정하고 오염정도를 약용부위별로 비교 분석하였다. 시료는 micro-wave 법을 이용하여 분해하였으며 납, 카드뮴, 비소는 유도 결합 플라즈마 질량분석기 (ICP/MS)를 이용하여 분석하였고 수은은 수은 분석기를 이용하여 측정하였다. 전체시료의 중금속 평균 함량은 납 0.870 (ND-69.200) mg/kg, 비소 0.148 (ND-2.965) mg/kg, 카드뮴 0.092 (ND-2.010) mg/kg, 수은 0.007 (ND-0.137) mg/kg으로 나타났다. 또한 납, 비소, 카드뮴, 수은을 합한 전체 중금속 함량을 기준으로 한 약용부위별 중금속 합계 평균함량은 줄기류 2.046 (0.065-4.474), 잎류 1.886 (0.048-10.404), 화류 1.874 (0.052-5.393), 표피류 1.377 (0.011-4.837), 뿌리류 1.165 (0.012-70.111), 뿌리줄기류 1.116 (0.016-5.490, 열매류 0.838 (0.017-4.527), 버섯류 0.729 (0.013-4.953), 종자류 0.646 (0.006-4.4 16)의 순으로 나타났다. 중금속 평균 함량은 뿌리류를 제외한 다른 부위에서 모두 국내산 한약재보다 수입산 한약재에서 다소 높게 나타났다. 기준을 초과한 이들 시료를 탕 액으로 만들어 탕제 전후의 중금속 함량을 측정하고 이행률을 산정한 결과 이행률 평균값은 납 6.1%, 비소 40.3%, 카드뮴 4.7%, 수은 2.2%로 나타나 탕제 후에 중금속 함량이 현저히 떨어지는 결과를 보였다. 본 연구결과는 시중 유통 중인 한약재에 대한 보다 세부적인 중금속 기준설정과 구체적인 품질관리를 위한 참고 자료로 활용될 수 있을 것으로 기대된다.

Keywords

References

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