Advances in Traditional Medicine

  • 제9권2호
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  • Pages.128-134
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  • 2009
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  • 2662-4052(pISSN)
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  • 2662-4060(eISSN)
경희대학교 융합한의과학연구소 (Kyung Hee Oriental Medicine Research Center)
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In vitro anti oxidant activity of methanol extract of Clerodendrum infortunatum Linn

  • Sannigrahi, Santanu (Department of Pharmaceutical Chemistry, College of Pharmaceutical Sciences) ;
  • Mazumder, Upal Kanti (Department of Pharmaceutical Technology, Jadavpur University) ;
  • Pal, Dilip Kumar (Department of Pharmaceutical Chemistry, Seemanta Institute of Pharmaceutical Sciences) ;
  • Parida, Sambit (Department of Pharmaceutical Chemistry, College of Pharmaceutical Sciences)
  • 발행 : 2009.06.30
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초록

The antioxidant potency of methanolic extract Clerodendrum infortunatum Linn. (MECI), which are widely used in the Indian indigenous system of medicine for different purposes, was studied. The antioxidant potential was evaluated using different established in vitro antioxidant tests viz. determination of total amount of polyphenolics compounds, DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging, nitric oxide scavenging, superoxide anion radical scavenging, hydroxyl radical scavenging and reductive power assay. It was found that MECI contain a high amount of polyphenolics and possesses significant free radical scavenging activity in all the assay. The higher activity was may be due to presence of richest amount of polyphenolics and flavonoids in it.

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