Clinical Results Following T3, 4 vs T3 Thoracoscopic Sympathicotomy in 30 Axillary Hyperhidrosis Patients

겨드랑이 다한증 환자에서 흉부교감신경의 차단부위(T3-4와 T4)에 따른 임상결과

  • Choi, Soon-Ho (Department of Thoracic and Cardiovascular Surgery, Wonkwang University Hospital, Wonkwang University School of Medicine) ;
  • Lee, Sam-Youn (Department of Thoracic and Cardiovascular Surgery, Wonkwang University Hospital, Wonkwang University School of Medicine) ;
  • Lee, Mi-Kyung (Department of Thoracic and Cardiovascular Surgery, Wonkwang University Hospital, Wonkwang University School of Medicine) ;
  • Cha, Byoung-Ki (Department of Thoracic and Cardiovascular Surgery, Wonkwang University Hospital, Wonkwang University School of Medicine)
  • 최순호 (원광대학교 의과대학 원광대학교병원 흉부외과학교실) ;
  • 이삼윤 (원광대학교 의과대학 원광대학교병원 흉부외과학교실) ;
  • 이미경 (원광대학교 의과대학 원광대학교병원 흉부외과학교실) ;
  • 차병기 (원광대학교 의과대학 원광대학교병원 흉부외과학교실)
  • Published : 2008.08.05

Abstract

Background: Video-assisted thoracic sympathicotomy is a definitive minimally invasive treatment for axillary hyperhidrosis. Different techniques exist for controlling axillary hyperhidrosis, but they are temporary and expensive. We compared the results after using two different levels of sympathicotomy for treating axillary hyperhidrosis: T3-T4 and T4. Material and Method: Between June 2002 and May 2007, 30 patients with isolated axillary hyperhidrosis underwent either T3-T4 or T4 thoracoscopic sympathicotomy in the Department of Thoracic & Cardiovascular Surgery at Wonkwang University Hospital. The patients were divided into two groups. Group I (n=15) was composed of patients who underwent T3-T4 sympathicotomy (thermal ablation), and Group II (n=15) was composed of patients who underwent T4 sympathicotomy (thermal ablation). The procedures were bilateral and simultaneous, involving the use of two 2-mm trocars and a 0-degree 2-mm thoracoscope under general anesthesia with single endotracheal intubation. Outcome parameters included satisfaction rate of treatment, degree of compensatory sweating, and postoperative complications. Patients were interviewed by telephone regarding satisfaction and compensatory hyperhidrosis. Result: There were no differences in age between group I and group II. The mean follow-up for the T3-T4 group was $38.7{\pm}2.3$ months, and the mean follow-up for the T4 group was $18.7{\pm}3.6$ months. The immediate therapeutic success rate (within 2 weeks postoperative) was 100% in both groups, and there were no recurrences in either group during the long-term follow-up period. The satisfaction rate was higher (93.3%) in the T4 group than in the T3-T4 group (53.3%), and the incidence of compensatory hyperhidrosis was lower in the T4 group (6.7%) than in the T3-T4 group (46.7%). Postoperative complications included one mild pneumothorax and two instances of intercostal neuralgia. Digital infrared thermographic imaging (DITI) correlated well with postoperative satisfaction. Conclusion: Both techniques proved effective for controlling isolated axillary hyperhidrosis. The T4 group had a higher satisfaction rate and lower severity of compensatory hyperhidrosis. Hence, thermal ablation of the lower interganglionic fibers of the third thoracic sympathetic ganglion on the fourth rib is a more practical and minimally invasive treatment than is the T3-T4 surgical method, according to the degree of compensatory sweating in isolated axillary hyperhidrosis.

배경: 비디오흉강경에 의한 흉부 교감신경차단술은 겨드랑이다한증을 치료하는데 최소침습 치료방법의 하나이다. 여러 다른 수기들이 겨드랑이다한증을 치료하는데 이용되고 있으나 효과가 일시적이고 고비용인 단점이 있다. 본 연구는 겨드랑이다한증 치료에 있어서 2개 부위의 흉부교감신경차단수술(T3-4대 T4)후 조기와 만기 결과를 비교하였다. 대상 및 방법: 2002년 6월부터 2007년 5월까지 원광대학교병원 흉부외과에서 겨드랑이다한증환자 30명에서 2개 부위(T3-4대 T4)의 흉부 교감신경차단 수술 후 후향적으로 조사를 하였다. 모든 환자에서 수술은 단일기도관을 이용한 전신마취하에서 양측으로 동시에 2개의 2 mm 투관침과 2 mm 흉강경을 이용하여 시행하였다. T3-4군은 2002년 6월부터 2004년 6월까지 15명으로 T3-4 교감신경차단수술을 늑골 3, 4번 늑골 상에서 시행하였고, T4군은 15명으로 4번 늑골 상에서 4번 흉부 교감신경차단수술을 시행하였다. 양군의 치료의 만족도, 보상성 다한증의 빈도와 정도, 그리고 술 후의 합병증을 조사하였고, 또한 T.I.P.I에 의한 술 전 후의 체열변화를 조사하였다. 만기의 결과는 환자와의 전화면담으로 시행하였다. 결과: 평균 추적기간은 T3-4군은 $38.7{\pm}6.5$개월, T3군은 $18.7{\pm}3.6$개월이었다. 수술 직후의 만족도는 양군에서 100%이었으나 만기의 만족도는 보상성다한증의 정도에 의해서 T3-4군은 53.3%,74군은 93.3%를 보였다. 보상성다한증은 불편한 정도 이상이 T3-4군은 46.7%를 보였으나 T4군은 6.7%를 보여 만기의 만족도는 보상성다한증의 정도와 일치하였다. 또한 T.I.P.I에 의한 체열검사에서는 양군 모두 의의 있는 체열상승을 보여주었다. 술 후의 합병증으로는 경도의 공기가슴증과 늑간신경통을 보였으나 모두 다 문제없이 해결되었다. 결론: 양 수술의 수기는 겨드랑이다한증을 치료하는 데 효과적이었다. T4교감신경차단수술이 보다 높은 만족도를 보였고 보상성다한증의 정도와 빈도는 낮았다.

Keywords

References

  1. Hsu CP, Shia SE, Hsia JY, et al. Experiences in thoracoscopic sympathectomy for axillary hyperhidrosis and osmidrosis. Arch Surg 2001;136:1115-7. https://doi.org/10.1001/archsurg.136.10.1115
  2. Gossot D, Debrosse D, Grunenwald D. Endoscopic thoracic sympathectomy for isolated axillary hyperhidrosis. Ann Dermatol Venereol 2000;127:1065-7.
  3. Gossort D, Toledo L, Fritsch S, et al. Thoracoscopic Sympa thectomy for upper limb hyperhidrosis: looking for the right operation. Ann Thorac Surg 1977;64:975-8. https://doi.org/10.1016/S0003-4975(97)00799-6
  4. Atkins JL, Butler PEM. Hyperhidrosis: a review of current management. Plast Recon Surg 2002;110:222-8. https://doi.org/10.1097/00006534-200207000-00039
  5. Probstle TM, Schneiders V, Knop J. Gravimetrically controlled efficacy of subcorial curettage: a prospective study for treatment of axillary hyperhidrosis. Dermatol Surg 2002; 28:1022-6. https://doi.org/10.1046/j.1524-4725.2002.02104.x
  6. Goldman A. Treatment of axillary and palmar hyperhidrosis with Botulinum toxin. Aesthetic Plast Surg 2000;24:280-2. https://doi.org/10.1007/s002660010046
  7. Kwong KF, Hobbs JL, Cooper LB, et al. Stratified analysis of clinical outcomes in thoracoscopic sympathicotomy for hyperhidrosis. Ann Thorac Surg 2008;85:390-4. https://doi.org/10.1016/j.athoracsur.2007.08.001
  8. Byrne J, Walsh TN, Hedermann WP. Endoscopic transthoracic electrocautery of the sympathetic chain for palmar and axillary hyperhidrosis. BJM 1990;77:1046-9.
  9. Rex LO, Drott C, Claes G, et al. The Boras experience of endoscopic thoracic sympathicotomy for palmar, axillary, facial hyperhidrosis and facial flushing. Eur J Surg 1998;580: S23-6.
  10. Jose RM, Paulo K, Nelson W, et al. Axillary hyperhidrosis: T3/T4 versus T4 thoracic sympathectomy in a series of 276 case. J Laparoend Adva Surg technique 2006;16:598-603. https://doi.org/10.1089/lap.2006.16.598
  11. Licht PB, Jorgensen OD, Ladegaard L, Pilegaard HK. Thoracoscopic sympathectomy for axillary hyperhidrosis; the influence of T4. Ann Thorac Surg 2005;80:455-60. https://doi.org/10.1016/j.athoracsur.2005.02.054
  12. Gossort D, Galetta D, Pascal A, et al. Long-term results of endoscopic thoracic sympathectomy for upper limb hyperhidrosis. Ann Thorac Surg 2003;75:1075-9. https://doi.org/10.1016/S0003-4975(02)04657-X
  13. Claes G. Indications for endoscopic thoracic sympathectomy. Clin Auton Res 2003;13:S16-9. https://doi.org/10.1007/s10286-003-0065-y
  14. Yoon YS, Kim YS, Cho YE, Cho KK. Determination of resection degree of upper thoracic sympathetic chain in essentil hyperhidrosis. Korean J Neuro Surg 1998;27:481-7.
  15. Gothberg G, Drott C, Claes G. Thoracoscopic sympathicotomy for hyperhidrosis-surgical technique, complication and side effects. Eur Surg 1994;S572:51-3.
  16. Hederman WP. Present and future trends in thoracoscopic sympathectomy. Eur J Surg Suppl 1994;572:17-9.
  17. Choi SH, Lim YH, Lee SY, Choi JB. Relation between changes of D.I.T.I. and clinical results according to the level and extent of sympathicotomy in essential hyperhidrosis. Korean J Thorac Cardiovasc Surg 2004;37:64-71.
  18. Kao MC. Complications in patients with palmar hyperhidrosis treated with transthoracic endoscopic sympathectomy. J Neurosurg 1998;42:951-2 https://doi.org/10.1097/00006123-199804000-00161
  19. Kao MC. Complications in patients with palmar hyperhidrosis treated with transthoracic endoscopic sympathectomy. J Neurosurg 1998;42:951-2 https://doi.org/10.1097/00006123-199804000-00161
  20. Hsu CP, Shia SE, Hsia JY, Chuang CY, Chen CY. Experiences in thoracoscopic sympathectomy for axillary hyperhidrosis and osmidrosis: focusing on the extent of sympathectomy. Arch Surg 2001;10:1115-7.