Clinial Analysis of Surgical Management for Descending Necrotizing Mediastinitis

하행 괴사성 종격동염의 수술적 치료에 대한 임상적 고찰

  • Yu, Jeong-Hwan (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University) ;
  • Lim, Seung-Pyung (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungbuk National University) ;
  • Lee, Seok-Ki (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University) ;
  • Kim, Yong-Ho (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University) ;
  • Kim, Si-Wook (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University) ;
  • Kang, Shin-Kwang (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University) ;
  • Yu, Jae-Hyeon (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University) ;
  • Lee, Young (Department of Thoracic and Cardiovascular Surgery, College of Medicine, Chungnam National University)
  • 유정환 (충남대학교 의과대학 흉부외과학교실) ;
  • 임승평 (충북대학교 의과대학 흉부외과학교실) ;
  • 이석기 (충남대학교 의과대학 흉부외과학교실) ;
  • 김용호 (충남대학교 의과대학 흉부외과학교실) ;
  • 김시욱 (충북대학교 의과대학 흉부외과학교실) ;
  • 강신광 (충남대학교 의과대학 흉부외과학교실) ;
  • 유재현 (충남대학교 의과대학 흉부외과학교실) ;
  • 이영 (충남대학교 의과대학 흉부외과학교실)
  • Published : 2008.08.05

Abstract

Background: Descending necrotizing mediastinitis (DNM) is a life-threatening cervico-mediastinal infection extending from the oropharynx or periodontal space. We reviewed clinical outcomes of DNM patients that underwent surgical management. Material and Method: We analyzed the demographic and surgical data from 8 patients (6 males and 2 females) that underwent surgical management for DNM between August 2003 and August 2007. Result: The mean age was $56.6{\pm}12.3$ ($34{\sim}72$) years, Types of DNM were I (n=2), IIA (n=1), and IIB (n=5), based on the classification system of Endo et al. Four patients were septic at the time of operation. The infectious organism was identified in three cases and turned out to be Streptococcus. ICU stay was $24.3{\pm}17.9$ ($3{\sim}58$) days, and hospital stay was $49.1{\pm}33.8$ ($20{\sim}125$) days, There were two deaths (25%), both of which were due to multi-organ failure. Conclusion: Despite aggressive surgical drainage and appropriate medical management, DNM still had a high mortality rate, Early diagnosis and prompt surgical intervention are key to DNM management. In addition, transcervical drainage should be used in limited disease only.

배경: 하행 괴사성 종격동염은 구강인두 및 치성부위로부터 발생하여 종격동으로 확산되는 생명을 위협하는 질환이다. 이에 저자는 수술적 치료를 받은 하행 괴사성 종격동염 환자의 치료결과를 조사하였다. 대상 및 방법: 2003년 8월부터 2007년 8월까지, 하행 괴사성 종격동염으로 수술적 치료를 받은 8명의 환자를 대상으로 수술결과에 대해 분석하였다. 결과: 환자군의 평균나이는 $56.6{\pm}12.3$ ($34{\sim}72$)세였다(남자: 6명, 여자: 2명). Endo 등의 분류에 따라 I형은 2예, IIA형은 1예, IIB형은 5예였다. 수술을 시행할 때 4예에서는 패혈증 소견을 보이고 있었다. 3예에서 연쇄상구균이 동정되었다. 집중치료실 기간은 $24.3{\pm}17.9$ ($3{\sim}58$)일, 재원일수는 $49.1{\pm}33.8$ ($20{\sim}125$)일이었다. 2예에서 다발성 장기부전으로 사망하여 약 25%의 사망률을 보였다. 결론: 적극적인 수술적 및 내과적 치료에도 불구하고, 하행 괴사성 종격동염은 여전히 높은 사망률을 보인다. 하행 괴사성 종격동염의 경우 조기 진단과 신속한 수술적 치료가 매우 중요하며, 아주 제한된 경우에서만 경부 배액술만을 시행할 수 있다.

Keywords

References

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