Korean Journal of Clinical Laboratory Science (대한임상검사과학회지)

Korean Society for Clinical Laboratory Science (대한임상검사과학회)
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The Effect of Saliva in Squamous Cell Carcinoma(SCC) and Thyroid Function Test with Radioimmunoassay

타액이 편평상피세포암(SCC)과 갑상선기능검사에 미치는 영향

  • Cho, Man Ick (Department of Nuclear Medicine, Seoul National University Bundang Hospital) ;
  • Moon, Ki Choon (Department of Nuclear Medicine, Seoul National University Bundang Hospital) ;
  • Kim, Hea Sook (Department of Nuclear Medicine, Seoul National University Bundang Hospital)
  • 조만익 (분당서울대학교병원 핵의학과) ;
  • 문기춘 (분당서울대학교병원 핵의학과) ;
  • 김혜숙 (분당서울대학교병원 핵의학과)
  • Published : 2004.12.31
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Abstract

Squamous cell carcinoma(SCC) associated antigen is a subfraction of TA-4, a tumor-associated antigen first described by Kato and Torigoe in 1977. TA-4, obtained from squamous cell carcinoma cancer tissue of the uterine cervix, has been characterized as a glycoprotein with a molecular weight of approximately 45,000 daltons. SCC antigen has been studied in other squamous cell malignancies including lung, esophagus, head and neck, anal canal, and skin. SCC antigen is shed naturally through sweat, saliva and other body fluids. Contamination of specimens, tray, bead dispenser or other accessories with sweat, saliva or aerosols can cause falsely elevated values. To reduce the possibility of contamination, gloves should be worn in all phases of assay preparation, and when handling specimens, accessories or reagents that will be used in SCC and Thyroid function test(TFT).

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