Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
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Enzymatic Synthesis of Glycosyl Acrylate and Methacrylate

배당화 아크릴레이트와 메타크릴레이트의 효소적 합성

  • Park, Dae-Won (Department of Chemical Engineering, Yonsei University) ;
  • Kim, Hae-Sung (Department of Chemical Engineering, Myongji University)
  • 박대원 (연세대학교 공과대학 화학공학과) ;
  • 김혜성 (명지대학교 공과대학 화학공학과)
  • Published : 2004.03.31
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Abstract

Glycosyl acrylate and methacrylate were synthesized by lipase-catalyzed esterification of vinyl acrylate and vinyl methacrylate with ${\beta}$-methyl glucoside in t-butanol as a reaction medium. At the optimum conditions of initial concentration of 150g/l ${\beta}$-methyl glucoside, molar ratio of 1 : 3, 5%(w/v) lipase(Novozym 435) and $50^{\circ}C$, we attained up to 100% conversion for enzymatic glycosylation of vinyl acrylate and vinyl methacrylate by supersaturated solvent process. The polymerizable glycosyl acrylates and methacrylate are expected to have biomedical application as hydrophilic monomers and hydration modifiers to be used for biocdmpatible hydrogel.

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