Microbiology and Biotechnology Letters (한국미생물·생명공학회지)

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Screening of Antimicrobial Substances against Brachyspira hyodysenteriae

Brachyspira hyodysenteriae에 대한 항균물질 탐색

  • Published : 2004.12.01
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Abstract

The extracts from 70 different plant natural products were used to investigate the antimicrobial activities against Brachyspira hyodrsenteriae, the causative agent of swine dysentery. Among them, the extracts from Terminalia chehula exhibited the highest antimicrobial activities against B. hyodysenteriae. It showed the antimicrobial activity against B. hyodysensteriae mostly in parts of its shell. Minimum inhibitory concentration (MIC) of the water extracts of T chehula was 12.5 mg/ml. After organic solvent extractions, the ethylacetate extracts exhibited higher antimicrobial activities against B. hyodysenteriae, and their antimicroactivities were similar to that of the tannin. In conclusion, these findings suggest that the extracts from T chebula may be used as animal feed additives for their antimicrobial activities against B. hyodysenteriae.

Keywords

References

  1. Ahmad, I. and A. Z. Beg. 2001. Antimicrobial and phytochemical studies on 45 Indian medicinal plants against multi-drug resistant human pathogens. J. Ethnopharmacol. 74: 113-123
  2. Cha, J. H. 1990. Practical oriental medicine. pp. 353. Ilwolseogak, Seoul, Korea. 353
  3. El-Mekkawy, S., M. R. Meselhy, I. T. Kusumoto, and S. Kadota. 1995. Inhibitory effects of Egyptian folk medicines on human immunodeficiency virus (HIV) reverse transcriptase. Chem. & Pharm. Bull. 43: 641-648
  4. Harris, D. L., D. J. Hampson, and R. Glock. 1999. Disease of swine, pp. 579-600. 8th ed. Blackwell Scientific Publications, Oxford
  5. Harris. D. L., and R. J. Lysons. 1992. Swine dysentery. pp. 599-616. 7th. ed. Iowa State Univ. Press. Ames, Iowa, USA
  6. Jagtap, A. G. and S. G. Karkera. 1999. Potential of the aqueous extract of Terminalia chebula as an anticaries agent. J. Ethnopharmacol. 68: 299-306
  7. Jang, S. J., G. D. Lee, J. S. Kim, and H. S. Yoon. 1992. Antioxidative effectiveness of Terminalia chebula Retz. Extracts. Agric. Res. Bull. Kyungpook Natl. Univ. 10: 11-17
  8. Karlsson, M., S. L. Oxberry, and D. J. Hampson. 2002. Antimicrobial susceptibility testing of Australian isolates of Brachyspira hyodysenteriae using a new broth dilution method. Vet. Microbiol. 84: 123-133
  9. Lee, H. S. 2004. Pathogenesis and prevention of swine dysentery. National Veterinary Research & Quarantine Service
  10. Lee, K. S., S. H. Kim, K. C. Sim, C. S. Park, and Y. S. Shin. 1997. Antimicrobial activity of Terminalia chebula Retz. Extract of against intestinal pathogens. Korean J. Food & Nutr. 10: 559-563
  11. Lee, S. I. 1990. Clinical Application of Oriental Medicine. pp. 392. Seongbosa, Seoul, Korea
  12. Malekzadeh, F., H. Ehsanifar, M. Shahamat, M. Levin, and R. R. Colwell. 2001. Antibacterial activity of black myrobalan (Terminalia chebula Retz) against Helicobacter pylori. Int. J. Antimicrob. Agents. 18: 85-88
  13. Moeslinger, T., R. Friedl, I. Volf, M. Brunner, E. Koller, and P. G. Spieckermann, 2000. Inhibition of inducible nitric oxide synthesis by the herbal preparation Padma 28 in macrophage cell line. Canadian J. Physiol. and Pharmacol. 78: 861-866
  14. Piddok, L. J. V. 1990. Techniques used for the determination of antimicrobial resistance and sensitivity in bacteria. J. Appl. Bacteriol. 68: 307-318
  15. Saleem, A., M. Husheem, P. Harkonen, and K. Pihlaja. 2002. Inhibition of cancer cell growth by crude extract and the phenolics of Terminalia chebula retz. fruit. J. Ethnopharmacol. 81: 327-336
  16. Sato, Y., H. Oketani, K. Singyouchi, T. Ohtsubo, M. Kihara, H. Shibata, and T. Higuti. 1997. Extraction and purification of effective antimicrobial constituents of Terminalia chebula Rets. against methicillin-resistant Staphylococcus aureus. Biol. & Pharm. Bull. 20: 401-404
  17. Sohni, Y. R., P. Kaimal, and R. M. Bhatt. 1995. The antiamoebic effect of a crude drug formulation of herbal extracts against Entamoeba histolytica in vitro and in vivo. J. Ethnopharmacol. 45: 43-52
  18. Stanton, T. B, E. G. Matson, and S. B. Humphrey. 2001. Brachyspira hyodysenteriae gyrB mutants and interstrain transfer of coumermycin A. resistance. Appl. Environ. Microbiol. 67: 2037-2043
  19. Tamhane, M. D., S. P. Thorat, N. N. Rege, and S. A. Dahanukar. 1997. Effect of oral administration of Terminalia Chebula on gastric emptying: an experimental study. J. Postgrad. Med. 43: 12-13