Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
권호 표지

Removal Torque and Histometric Evaluations of Implants with Various Area of Hydroxyapatite Coating Placed in the Rabbit Tibia

토끼 경골에서 hydroxyapatite 코팅의 면적에 따른 임프란트의 뒤틀림 제거력과 조직계측학적 분석

  • Moon, Sang-Kwon (Dept. of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University) ;
  • Cho, Kyoo-Sung (Dept. of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Brain Korea 21 Project for Medical Science, Yonsei University) ;
  • Ahn, Sae-Youn (Institute of Biomedical Engineering, Solco Biomedical Co., Ltd) ;
  • Lee, Hoon (Institute of Biomedical Engineering, Solco Biomedical Co., Ltd) ;
  • Kim, Han-Sun (Dept. of Biomedical Engineering, College of Health Sciences, Yonsei University) ;
  • Shim, June-Sung (Dept. of Prosthodontics, College of Dentistry, Yonsei University) ;
  • Choi, Seong-Ho (Dept. of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Brain Korea 21 Project for Medical Science, Yonsei University)
  • 문상권 (연세대학교 치과대학 치주과학교실, 치주조직 재생연구소) ;
  • 조규성 (연세대학교 치과대학 치주과학교실, 치주조직 재생연구소, BK21 의과학 사업단) ;
  • 안세영 (솔고바이오메디칼 의공학연구소) ;
  • 이훈 (솔고바이오메디칼 의공학연구소) ;
  • 김한성 (연세대학교 보건과학대학 의공학부) ;
  • 심준성 (연세대학교 치과대학 보철과학교실) ;
  • 최성호 (연세대학교 치과대학 치주과학교실, 치주조직 재생연구소, BK21 의과학 사업단)
  • Published : 2003.12.31
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Abstract

Background: This study presents a biomechanical and histometric comparison of bone response to implants with various area of hydroxyapatite(HA) coating. Methods: The implants were placed in the tibia of 10 rabbits weighing 2.5-3.5kg. The control group had a machined surface, the experimental group 1 had 50${\mu}m$ thick HA coated in a band form, and the experimental group 2 had 50${\mu}m$ thick HA coated on the entire surface. 8 weeks after implantation, the animals were sacrificed. Removal torque was measured and histologic preparation was also performed for histologic and histometric analysis. Bone to implant contact as well as percentage of bone area inside threads were measured. ANOVA post hoc, and t-test were used for statistical analysis with p-value p<0.05. Results: 1. The removal torques were 9.36${\pm}$5.64 Ncm, 48.40 ${\pm}$ 16.66 Ncm, and 82.37${\pm}$22.56 Ncm for the control, exp. 1, and exp. 2 group respectively. Statistically significant difference were found among all the groups(p<0.05). 2. Bone to implant contact in the cortical bone were 38.94${\pm}$10.9 %, 66.90${\pm}$14.1 %, 73.00${\pm}$19.4 %, in the marrow bone, 8.30${\pm}$5.4%, 14.59${\pm}$5.9%, 18.54${\pm}$11.8%, and in total, 22.40${\pm}$10.1%, 31,17${\pm}$7.5%, 41.41${\pm}$12.2% for the control, exp. 1, and exp. 2 group respectively . In the cortical bone, exp. 1, and exp. 2 group showed statistically significantly higher contact compared to control group. Total contact and in the marrow bone, only exp. 2 group showed statistically significantly higher contact compared to control group(p<0.05). In all the groups significantly higher contact were observed in the cortical bone compared to the marrow bone(p<0.05). 3. Percentage of bone area inside threads in the cortical bone were 55.68${\pm}$7.25%, 55.19${\pm}$13.19%, 57.04${\pm}$13.33%, in the marrow bone, 12.34${\pm}$14.61%, 17.56${\pm}$20.04%, 20.26${\pm}$12.83%, and in total, 30.30${\pm}$12.46%, 31.57 ${\pm}$15.15%, 34.25${\pm}$12.56% for the control, exp.1, and exp. 2 group respectively. There was no statistical difference among the groups. In all the groups significantly higher bone area were observed in the cortical bone compared to the marrow bone(p<0.05)

Keywords

References

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