Biotechnology and Bioprocess Engineering:BBE

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
권호 표지

Nanoparticle-based Detection Technology for DNA Analysis

  • Park, Hyun-Gyu (Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology)
  • Published : 2003.07.01
Download PDF
⟨ Previous Next ⟩

Abstract

With the current rapid development of nanotechnology and synthesis technology for designed oligonucleotides or oligonucleotide-modified nanoparticle conjugates, the combined strategies have become one of the most valuable methods in detection technology for DNA analysis. Using the uniquely recognizable interactions of pre-designed DNA molecules in assembling nanoparticles, various novel approaches have been recently developed towards detecting specific DNA sequences. Here we describe the key fundamentals and issues of this promising strategies ranging from the initial findings of rationally designed DNA-based assembly of nanoparticles to the extended chip-based detection system. Some limitations of these new strategies and possible approaches will be also discussed for the practical application in the area of DNA microarray detection.

Keywords

References

  1. Science v.293 Optics in the nono-world Koch,S.W;A.Knorr https://doi.org/10.1126/science.1065119
  2. Na-ture v.407 Nano-sized transition-metal oxides as negative-electrode materials for lithium-ion batteries Poizot,O;S.Laruelle,S;Grugeon;L,Dupont;J.-M.Tarascon
  3. Nature v.414 Nanotechnology:Synthesis of carbon 'onions'in water Sano,N;H.Wang;M.Chhowalla;I.Alexandrou;G.A.J.Amaratunga
  4. Nature v.382 Or-ganization of 'nanocrystal molecules'using DNA Alivisatos,A.P;K.P.Johnson;X.Peng;T.Wilson;C.J.Loweth;M.P.Bruchez Jr;P.G.Schultz https://doi.org/10.1038/382609a0
  5. Nature v.382 A DNA-based method for rationally assem-bling nanoparticles into macroscopic materials Mirkin,C.A;R.L.Letsinger;R.C.Mucic;J.J.Stor-hoff https://doi.org/10.1038/382607a0
  6. Science v.177 Selective colorimetric detection of polynucleotides based on the distanse-dependent optical properties of gold nanoparticles Elghanian,R;J.J.Storhoff;R.C.Mucic;R.L.Letsinger;C.A.Mirkin https://doi.org/10.1126/science.177.4054.1078
  7. J.Am.Chem.Soc v.120 One-pot colorimetric differen-tiation of polynucleotides with single base imperfections using gold nanoparticle probes Storhoff,J.J;R.Elghanian;R.C.Mucic;C.A.Mikron;R.L.Letsinger https://doi.org/10.1021/ja972332i
  8. Science v.289 Scanometric DNA array detection with nanoparticle probes Taton.T.A;C.A.Mirkin;R.L.Letsinger https://doi.org/10.1126/science.289.5485.1757
  9. J.Am.Chem.Soc v.122 Homogeneous,nanoparticle-based quantitative colorimetric detection of oligonucleotides Reynold,Ⅲ,R.A;C.A.Mikron;R.L.Letsinger https://doi.org/10.1021/ja000133k
  10. J.Am.Chem.Soc v.123 Two-color labeling of oligonucleotide arrays via size-selective scatter-ing of nanoparticle probes Taton,T.A;G.Lu;C.A.Mikron https://doi.org/10.1021/ja0102639
  11. J.Am.Chem.Soc v.120 DNA-directed synthesis of binary nanoparticle network materials Mucic,R.C;J.J.Storhoff;C.A.Mirkin;R.L.Letsinger https://doi.org/10.1021/ja982721s
  12. J.Am.Chem.Soc v.123 DNA-modified core-shell Ag/Au nanoparticles Cao.Y.W;R.Jin;C.A.Mikron
  13. Angew.Chem.Int.Ed v.40 Directed assembly of periodic materials from protein and oligonucleotide-modified nanoparticle buliding blocks Park,S.J;A.A.Lazarides;C.A.Mirkin;R.L.Letsinger https://doi.org/10.1002/1521-3773(20010803)40:15<2909::AID-ANIE2909>3.0.CO;2-O
  14. Nucleic Acids Res v.30 Multiple thiol-anchor capped DNA-gold nanoparticle con-jugates Li,Z;R.Jin;C.A.Mirkin;R.L.Letsinger https://doi.org/10.1093/nar/30.7.1558
  15. Anal.Chem v.72 Chip-based optical detection of DNA hybridization by means of nanobead labeling Reichert,J;A.Csaki;J.M.Kohler;W.Fritzsche https://doi.org/10.1021/ac000567y
  16. Colloid Polym.Sci v.279 Site-selective immobilization of gold nanoparticles functionalized with DNA oligomers Niemeyer,C.M;C.Ceyhan;S.Gao;L.Chi;S.Peschel;U.Simon https://doi.org/10.1007/s003960000429
  17. Nucleic Acids Res v.29 DNA monolayer on gold substrates char-acterized by nanoparticle labeling and scanning force mi-croscopy Csaki,A;R.Moller;W.Straube;J.M.Kohler;W.Fritzsche https://doi.org/10.1093/nar/29.16.e81
  18. Sens.Actuat.B v.76 Selective labeling of oligonucleo-tide monolayers by metallic nanobeads for last optical readout of DNA-chips Kohler,J.M;A.Csaki;J.Reichert;R.Moller;W.Straube;W.Fritzsche https://doi.org/10.1016/S0925-4005(01)00619-0
  19. Chem.Rev v.99 Programmed mate-rials synthesis with DNA Storhoff,J.J;C.A.Mirkin https://doi.org/10.1021/cr970071p