Abstract
Objectives : To investigate the role of Meridian flow on acupuncture effect, we observed the therapeutic effects of electroacupuncture (EA) after Meridian blocking with pressure in arthritic rats. Methods : To make reliable and local monoarthritis, $40{\;}{\mu}l$ complete Freund's adjuvant was injected into the tibio-tarsal joint. EA was applied on acupoint GB30 while 5 Pascal pressure was added to the middle of the Gall bladder Meridian around GB31 between acupoint GB30 and arthritic foci (ipsilateral meridian blocking: IB) or opposite part of IB (contralateral part blocking: CB). To observe the change of arthritis, extension and flexion pain scores and circumferential differences were evaluated once a week. Results : EA stimulation without blocking reduced arthritic pain significantly. IB abolished the acupuncture effects and there was no statistical difference with the arthritic control group, whereas the CB group still showed the therapeutic effects of acupuncture. Conclusions : This finding strongly supports that the Meridian blocking with local pressure reduced the therapeutic effect of EA.