Biotechnology and Bioprocess Engineering:BBE

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Development of a Supported Emulsion Liquid Membrane System for Propionic Acid Separation in a Microgravity Environment

  • Li, Jin (The University of Iowa, Department of Chemical and Biochemical Engineering, 4122 Seamans Center, Iowa City, IA52241, USA) ;
  • Hu, Shih-Yao B. (The University of Iowa, Department of Chemical and Biochemical Engineering, 4122 Seamans Center, Iowa City, IA52241, USA) ;
  • Wiencek, John M. (The University of Iowa, Department of Chemical and Biochemical Engineering, 4122 Seamans Center, Iowa City, IA52241, USA)
  • Published : 2001.12.01
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Abstract

Perstractive fermentation is a good way to increase the productivity of bioreactors. Us-ing Propionibacteria as the model system, the feasibility of using supported emulsion liquid mem-brane(SELM) fro perstractive fermentation is assessed in this study. Five industrial solvents were considered as the solvent for perparing the SELM. The more polar a solvent, is the higher the par-tition coefficeint However, toxicity of a solvent also increases with its polarity. CO-1055(indus-trial decanol/octanol blend)has the highest partition coefficient toward propionic acid among the solvents that has no molecular toxicity toward Propionibacteria, A preliminary extraction study was conducted using tetradecane as solvent in a hydrophobic hollow fiber contactor. The results confirmed that SELM eliminates the equilibrium limitation of conventional liquid-liquid extrac-tion and allows the use of a non-toxic solvent with low partition coefficient.

Keywords

References

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