Korean Journal of Pharmacognosy (생약학회지)
- Volume 29 Issue 3
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- Pages.179-186
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- 1998
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Anticonvulsant Effect of Uncariae Ramulus et Uncus II. - Effects of Methanol Extract and Ethyl Acetate Fraction on Neurotransmitters related Components in Brain -
조구등 성분의 항경련효과 II. - 메탄올 추출물 및 에틸 아세테이트 분획의 뇌 신경전달 관련물질에 미치는 효과 -
- Kim, Dong-Young (College of Pharmacy, Kyungsung University) ;
- Park, Jong-Cheol (Department of Oriental Medicine Resources, Sunchon Natinal University) ;
- Lee, Chung-Kyu (College of Pharmacy, Kyungsung University) ;
- Choi, Jong-Won (College of Pharmacy, Kyungsung University)
- Published : 1998.09.30
Abstract
The fractions of Uncariae Ramulus et Uncus seemed to be closely related with the levels of amino acids and other components which concerns with formation and metabolism of neurotransmitters in brain. The pretreatments of methanolic extract and its fractions prohibited the pentylenetetrazole (PTZ) induced convulsion. In such cases, lowered levels of