The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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Cytotoxicity of Carthami Flos on Human cancer cell-lines(I)

홍화(紅花)가 인체(人體)의 암세포주(癌細胞柱)에 미치는 영향(影響)

  • Han, Jong-Hyun (Medicinal Resources Research Center of Wonkwang University) ;
  • Yoo, Kwang-Suk (Medicinal Resources Research Center of Wonkwang University) ;
  • Kang, Sung-Young (College of Oriental Medicine, Dongshin University)
  • 한종현 (원광대학교 의약자원연구센터) ;
  • 유광석 (원광대학교 의약자원연구센터) ;
  • 강성용 (동신대학교 한의과대학)
  • Published : 1996.10.30
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Abstract

The purpose of this study was to investigate effect of water extract of Carthami Flos on the proliferation of human cancer cell-lines. The effects of Carthami Flos on the proliferation of A431, HeLa, MOLT-4, K562 cells, Balb／c 3T3 cells, mouse thymocytes, splenocytes and human lymphocytes were estimated by MTT colorimetric assay. The results were as follows; 1. Carthami Flos did not effect A431, HeLa, MOLT-4, K562 cells. 2. The cytotoxicity of mitomycin C on K562 cells was increased by the combination of Carthami Flos. 3. Carthami Flos inhibited the proliferation of Balb／c 3T3 cells. 4. Carthami Flos stimulated the proliferation of thymocytes. 5. Carthami Flos stimulated the proliferation of splenocytes. 6. Carthami Flos stimulated the proliferation of human lymphocytes.

Keywords

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