The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
권호 표지

Effects of Cervus elaphus for herb-acupuncture solution on Antioxidation in Rat‘s liver

흰쥐의 간(肝) 조직(組織)에서 녹용(鹿茸) 약침(藥針) 제제(製劑)의 항산화작용(抗酸化作用)에 관(關)한 연구(硏究)

  • Yoon, Cheol-Ho (Dept. of Internal Medicine, College of Oriental Medicine, Dongguk Univ.) ;
  • Jeong, Ji-Cheon (Dept. of Internal Medicine, College of Oriental Medicine, Dongguk Univ.) ;
  • Shin, Uk-Seob (Dept. of Pharmacy, Dongguk Medical Center)
  • 윤철호 (동국대학교 한의과대학 내과학교실) ;
  • 정지천 (동국대학교 한의과대학 내과학교실) ;
  • 신억섭 (동국대학교 의료원 약제과)
  • Published : 1996.10.30
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Abstract

Cervus elaphus for herb-acupuncture solution(CEHAS) was tested for the effects of free radical generating enzyme and lipid peroxidation in rat's liver. In vitro, levels of lipid peroxide in tissues of liver were proportionally decreased to concentration of CEHAS. They were much more decreased. when lipid peroxidation was induced with ferrous iron $(Fe^{-2})$. Also, enzyme activities of xanthine oxidase were decreased. The ratio of type conversion of xanthine oxidase was lowered, too. But, here was not special changes on enzyme activities of aldehyde oxidase. These results suggest that CEHAS decrease the activities of free radical generating enzymes such as xanthine oxidase which form lipid peroxide.

Keywords

References

  1. 經絡(4) 南相千
  2. 臨床本草學 辛民敎
  3. 家庭醫學 醫學敎育硏修院(編)
  4. 漢藥臨床應用 李尙仁(外)
  5. 鍼灸學(下) 최용태(外)
  6. 慶熙大學校大學院 博士學位論文 鹿茸，熟地黃，人蔘，五加皮가 免疫反應 및 NK細胞活性度에 미치는 影響 高炳熙
  7. 慶熙大學校 大學院 碩士學位論文 鹿茸水鍼이 白鼠의 副腎皮質機能不全에 미치는 影響 金甲麗
  8. 慶熙大學校 大學院 博士學位 論文 鹿茸類가 白鼠의 內分泌機能에 미치는 影響 金敬彬
  9. 慶熙大學校 大學院 碩士學位論文 人蔘 및 鹿茸水鍼이 免疫機能에 미치는 影響 金卿顯
  10. 慶山大學校大學院 博士學位論文 鹿茸 및 六味地黃湯加鹿茸이 白鼠의 運動抑制性 骨多孔症에 미치는 影響 金根模
  11. 慶熙大學校 大學院 博士學位論文 鹿茸，人參 및 靈芝水鍼이 免疫反應에 미치는 影響 金大洙
  12. 仁荷大學校 大學院 博士學位論文 鹿茸 有效分劃이 생쥐의 造血系에 미치는 免疫生物學的 硏究 金美貞
  13. 慶熙大學校大學院 碩士學位論文 鹿茸投與가 白鼠의 血淸 蛋白質 含量 및 Prothrombin time에 미치는 影響 金容熙
  14. 建國大學校 農畜大學院 碩士學位論文 랫트의 造血 機能에 미치는 鹿茸의 影響에 對한 硏究 金璨圭
  15. 漢陽大學校 大學院 博士學位論文 鹿茸이 動脈硬化症에 미치는 影響에 關한 實驗的 硏究 閔勝源
  16. 東國大學校 大學院 碩士學位論文 鹿茸 藥針 刺戟이 흰쥐의 高脂血症에 미치는 影響 朴基腕
  17. 慶熙大學校 大學院 博士學位論文 鹿茸이 Streptozotocin糖尿에 미치는 影響에 對한 免疫組織學的 硏究 朴鍾賢
  18. 東義大學校 大學院 碩士 學位論文 鹿茸 水鍼이 副腎皮質機能低下에 미치는 影響 朴重秀
  19. 慶山大學校 大學院 博士學位論文 六味地黃湯 및 鹿茸加味方이 흰쥐 糖尿에 對한 免疫組織化學的 硏究 卞晟僖
  20. 慶熙大學校 大學院 博士學位論文 鹿茸，黃芝，當歸水鍼이 放射線 被曝에 의한 免疫機能 低下에 미치는 影響 李栽東
  21. 梨花女子大學校 大學院 碩士學位論文 鹿茸中에 存在하는 脂質 및 Gangliosides에 關한 硏究 韓娜英
  22. 慶熙大學校 大學院 碩士學位論文 人蔘 및 鹿茸水鍼의 時問經過에 따른 免疫效果 硏究 黃慶愛
  23. 생화학 뉴스 v.5 no.3 노화의 메카니즘과 연구방향 최진호
  24. 重修政和經史證類備用本草 唐縝微
  25. 名醫別錄 陶弘景
  26. 神農本草經 孫星衍;孫馮翼(輯)
  27. 中醫長壽學 王其飛(外)
  28. 本草綱目(下) v.25 no.26項 李時珍
  29. 中草藥注射劑 錢百炎(外)
  30. 中西醫結合雜誌 v.10 no.8 腎虛，衰老與自由基的關係以及補腎葯對自由基的影響 梁曉春(外)
  31. 中國中西醫結合雜誌 v.12 no.1 五子衍宗液延緩衰老的臨床觀察 王學美(外)
  32. 上海中醫藥雜誌 no.6 祖國醫學抗老年齡問題初探 姚培發
  33. 中醫雜誌 v.25 no.5 鹿茸精注射液治療老年脾腎陽虛泄瀉11例 張桂寶
  34. 中醫雜誌 v.30 no.2 老年腎虛證血漿過氣化脂質高密度脂蛋白膽固醇及其亞組分水平變化 張文彭(外)
  35. 中醫雜誌 v.30 no.3 淸宮長春丹對老年腎虛證血漿過氣化脂質高密度脂蛋白膽固醇水平影響的硏究 張文彭(外)
  36. 中國中藥雜誌 v.16 no.3 六味地黃湯及其配伍對過氣化脂質及脂褐質含量的影響 蔣莹(外)
  37. FASEB J. v.1 Oxidants and human disease;Some new concepts Barry, H.
  38. Biochem. J. v.131 Milk xanthine oxidase type D(dehydrogenase) and type O(oxidase):Purification and interconversion and some properties Batteli, N.G.;Lorenzoni, E.;Stirpe, F.
  39. J. Biol. Chem. v.245 A mechanism for the production of ethylene fbom methional:The generation of the hydroxyl radical by xanthine oxidase Beauchamp, C.;Fridov ich, I.
  40. Free Radicals in Biology v.6 Antioxidants, aging and longevity Cutler, R.G.
  41. J. Pharm. Pharmacol. v.41 Mechanistic toxicology:A radical perspective David, R.
  42. Free Radicals Reactions in Medicine The free radical theory of aging Feher, J.;Csomos, G.;Vereckei, A.
  43. Free Radicals, Aging and Degenerative Disease Free radical theory of aging;Role of free radicals in the organization and evolution of life, aging and disease processes Harman, D.;Johnson, J.E.(et al.)
  44. Biochem. Physiol. v.49B A comparison of the distribution and electron acceptor specificities of xanthine oxidase and aldehyde oxidase Comp Kreidntsky, T.A.;Tuttle, J.V.;Cattau, E.L.;Wang, P.
  45. Free radicals, aging and degenerative disease Larry, W.O.;Terry, B.O.
  46. J. Biol. Chem. v.193 Protein measurement with folin phenol reagent Lowry, O.H.;Rosebrough, N.J.;Farr, A.L.;Randall, R.J.
  47. Biochem. Biophys. Res. Comm. v.36 The production of superoxide anion radicals in the reaction of reduced flavins and flavoprotein with molecular oxygen Massey, V.;Strickland, S.;Mayhew, S.G.;Howell, L.G.;Engel, P.C.
  48. Free radicals in chemistry and biology Milan, L.;Jozef, R.;Vilian, K.;Peter, P.;Ladislav, V.
  49. Eur. J. Biochem. v.82 Do mitochondria produce oxygen radical in vivo? Nohl, H.;Hegener, D.
  50. Anal. Biochem. v.95 Assay for lipid peroxide in animal tissues by thiobarbituric acid reaction Ohkawa, H.;Ohishi, N.;Yaki, K.
  51. Acta Physiol. Scand. v.548 no.SUP. Xnathine oxidase:biochemistry, distribution and physiology Parks, D.A.;Granger, D.N.
  52. Free radical in biology:Involvement of radical reaction in aging and carcinogenesis in medicinal chemistry Pryor, W.A.
  53. Lipids v.11 Autoxidation of polyunsaturated fatty acids(II) Pryor, W.A.;Stanley, T.P.;Blair, E.
  54. J. Biol. Chem. v.237 Hepatic aldehyde oxidase. I. Purification and properties Rajagopalan, K.V.;Fridovich , I.;Handler, P.
  55. J. Biol. Chem. v.266 Hydrogen peroxide cause the tafal injury to human fibroblasts exposed to oxygen radicals Simon, R.H.;Scogging, C.M.;Patterson, D.
  56. J. Biol. Chem. v.244 The regulation of rat liver xanthine oxidase:Conversion in vitro of the enzyme activity from dehydrogenase(type D) to oxidase(type O) Stirpe, F.;Della Corte, E.
  57. Chem. and Phys. of Lipid. v.45 Lipid peroxides and disease Yagi, K.