Effects of Lycii Fructus Water Extracts on the Blood Pressure, Plasma Renin Activity and Plasma Levels of Atrial Natriuretic Peptide in Two-Kidney One Clip Goldblatt Hypertensive Rats

구기자(枸杞子) 전탕액(煎湯液)이 실험적(實驗的) 신성(腎性) 고혈압(高血壓) 백서(白鼠)의 혈압(血壓)과 혈장(血漿) Renin 활성도(活性度) 및 ANP 농도(濃度)에 미치는 영향(影響)

  • 이호섭 (원광대학교 한의과대학 생리학교실) ;
  • 류도곤 (원광대학교 한의과대학 생리학교실) ;
  • 윤용갑 (전주 갑자원 한의원) ;
  • 유윤조 (우석대학교 한의과대학 생리학교실)
  • Published : 1996.04.30

Abstract

The aim of this experiments was to investigate the effect of Lycii Fructus water extracts on the blood pressure, plasma renin activity and plasma levels of atrial natriuretic peptide in two-kidney one clip Goldblatt hypertensive rats. Systolic blood pressure was decreased significantly after administration of Lycii Fructus water extracts. Plasma levels of atrial natriuretic peptide was increased significantly after adminstration of Lycii Fructus water extracts. Plasma renin activity was not changed after adminstration of Lycii Fructus water extracts. Thease results suggested that the depressor response after adminstration of Lycii Fructus water extracts were related with the changes of the plasma levels of atrial natriuretic peptide.

Keywords

References

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