Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Isolation and Characterization of 4-hydroxycinnamic Acid with Antimicrobial Activity from Aralia eiata

두릅에서 항미생물활성을 갖는 4-hydroxycinnamic acid의 분리 및 동정

  • Ma, Seung-Jin (Department of Food Science and Technology, Chonnam National University) ;
  • Kuk, Ju-Hee (Department of Food Science and Technology, Chonnam National University) ;
  • Ko, Byoung-Seob (Korea Institute of Oriental Medicine) ;
  • Park, Keun-Hyung (Department of Food Science and Technology, Chonnam National University)
  • Published : 1996.08.30
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Abstract

The methanol extracts of AraIia elata showed antimicrobial activity against bacteria. The antimicrobial active principle was successively purified with solvent fractionation, silica gel adsorption column chromatography, Sephadex LH-20 column chromatography, silica gel partition column chromatography and HPLC. The active substance was isolated by HPLC on $C_{18}$ column with an acetic acid-MeOH system. The active substance was identified as trans-4-hydroxycinnamic acid by MS, $^1H-NMR\;and\;^{13}C-NMR$.

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