YAKHAK HOEJI (약학회지)
- Volume 38 Issue 5
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- Pages.516-519
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- 1994
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Analysis of Methyl 5-Hydroxy-dinaphtho[1,2-2',3']furan-7,12-dione-6-Carboxylate Derivatives
메틸 5-하이드록시 디나프토[1,2-2',3']푸란-7,12-디온-6-칼복시레이트 유도체의 분리 분석
- Woo, Young-Ah (College of Pharmacy, Seoul National University) ;
- Kang, Kyoung-Hwan (College of Pharmacy, Seoul National University) ;
- Shin, Joon-Su (College of Pharmacy, Seoul National University) ;
- Jang, Hae-Seon (College of Pharmacy, Seoul National University) ;
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Kim, Bak-Kwang
(College of Pharmacy, Seoul National University)
- Published : 1994.10.30
Abstract
The derivatives of methyl 5-hydroxy-dinaphtho[1,2-2',3']furan-7,12-dione-6-carboxylate (MHDDC) were synthesized by condensing alkyl sulfate or alkyl halide with MHDDC in organic solvent, and their structures were identified by NMR, MS, UV, IR etc. We also investigated the physico-chemical properties, physiological activities, and set up the micro-analytical method of the compounds.
Keywords
- Methyl 5-hydroxy-dinaphtho1,2-2,,3,furan-7,12-dione-6-carboxyl-ate(MHDDC);
- dime-thylsulfate;
- ethyliodide;
- propylbromide;
- butylbromide;
- o-alkylation;
- HPLC