Journal of the Korean Academy of Child and Adolescent Psychiatry

Korean Academy of Child and Adolescent Psychiatry (대한소아청소년정신의학회)
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SEASON OF BIRTH, BIRTH ORDER AND MATERNAL AGE IN INFANTILE AUTISM

유아(幼兒) 자폐증(自閉症)의 출생계절(出生季節), 출생순위(出生順位)및 산모연령(産母年齡)에 관한 연구(硏究)

  • Lee, Young-Sik (Department of Neuropsychiatry, College of Medicine, Chung-Ang University) ;
  • Min, Kyung-Joon (Department of Neuropsychiatry, College of Medicine, Chung-Ang University) ;
  • Choi, Jin-Sook (Yong-In Mental Hospital) ;
  • Kim, Dong-Hyun (Division of Child-Adolescent Psychiatry, Seoul National University, Children's Hospital) ;
  • Cho, Soo-Churl (Division of Child-Adolescent Psychiatry, Seoul National University, Children's Hospital) ;
  • Lee, Kil-Hong (Department of Neuropsychiatry, College of Medicine, Chung-Ang University) ;
  • Hong, Kang-E (Division of Child-Adolescent Psychiatry, Seoul National University, Children's Hospital)
  • Published : 1993.12.31
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Abstract

To find some involvement of environmental factors in autism, season of birth, birth order, and maternal age at birth of autistic children were investigated Total number of clinical outpatient autistic children was 357, which consisted of 319 male and 38 female, then male-to-female sex ratio was 8.4 to 1, and all subjects were born during $1986{\sim}1988.$ These data were compared with those of controlled general populations. The results were as follows : 1) In monthly and seasonal distributions of birth, autistic children were not different from normal control 2) Comparing with control group by Slater's and Greenwood-Yule's birth order calculation methods, there was no significant difference in birth order of autistic children 3) The maternal ages at birth in autistic group were significantly higher than those of control group(P<01) 4) High-risk pregnancies were significantly frequent in autistic group compared with control group(p<01)Our study supported the idea that at least some environmental factors, especially at-risk pregnancy, are involved in autism causation.

본 연구는 $1990 1 1{\sim}1992 12 31$ 기간 중 서울대학 어린이 병원 소아정신과와 중앙 대학부속 용산병원 소아청소년 크리닉을 방문한 자폐아동 중에서 1986년 및 1988년에 출생한 환자를 대상으로 하여 출생계절 및 출생순위, 자폐아 출산 당시의 산모 연령에 어떤 특이점이 있는지를 알아보기 위해 일반 인구집단의 출생자료와 비교하여 다음과 같은 결론을 얻었다. 1) 자폐아군은 총 357명이었으며 이중 남아가 319명 (89.4%), 여아가 38명(10.4%)으로 남녀 성비는 8.4:1이었다.2) 자폐아군의 월별분포나 계절별분포에 있어 대조군과 차이가 없었다. 3) Slater 및 Greenwood-Yule 방법에 의한 자폐아군의 출생순위를 대조군과 비교 분석한 결과 통계적으로 유의한 차이는 없었다.4) 자폐아군은 일반 대조군에 비해 출생 당시의 산모의 연령이 통계적으로 의미있게 높았다(p<01) 5) 출산의 위험도가 높은 임신은 일반 대조군에 비해 자폐아군에서 통계적으로 의미있게 많았다(p<01)

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