Studies on the Efficacy of Combined Preparation of Crude Drugs (XXII) -Effects of Yijin-Tang on the Digestive System and Isolated Uterus-

생약(生藥) 복합제제(複合製劑)의 약효(藥效) 연구(硏究)(제22보)(第22報) -이진탕(二陳湯)이 소화기계(消化器系) 및 적출자궁(摘出子宮)에 미치는 영향(影響)-

Experimental studies were undertaken to investigate for the effect of Yijin-tang on the digestive system and isolated uterus of rats. Yijin-tang was composed of five crude drugs; Pinelliae Tuber, Aurantii nobilis Pericarpium, Hoelen, Glycyrrhizae Radix and Zingiberis Rhizoma. The results obtained from experiments with water soluble fraction extracted from Yijin-tang were as follows; Spontaneous motilities of isolated ileum of mice and rabbits were suppressed, and contraction of isolated ileum of mice and guinea-pigs induced acetylcholine, barium chloride and histamine were inhibited. The anticathartic action of mice induced by castor oil were significantly observed. The spontaneous motility of isolated uterus of rats was suppressed. Inhibitory effect of gastric juice secretion and antiulcerogenic action were significantly shown in Shay rats.