대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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- Pages.122.2-122.2
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- 2003
Induction of cyclooxygenase-2 by collagen and gelatin in murine macrophages
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Kim, Ji-Young
(Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun University)
;
- Moon, Ae-Ran (Division of Food Science, Jinju International University) ;
- Kim, Hyung-Gyun (Division of Food Science, Jinju International University) ;
- Choi, Chul-Yung (Division of Food Science, Jinju International University) ;
- Chung, Yung-Chul (Division of Food Science, Jinju International University) ;
- You, Ho-Jin (Division of Food Science, Jinju International University) ;
- Jeong, Hye-Gwang (Division of Food Science, Jinju International University)
- 발행 : 2003.10.01
초록
Gelatin protein is derived from animal collagen tissues and is therefore present in many kinds of animal protein food. The biological origin and biocompatibility of gelatin has led to wide-ranging applications in the pharmaceutical and medical fields; for example, as sealants for vascular prostheses, bone-repairing materials, wound healing agents and scaffolds for tissue engineering purposes. In the present study, we investigated the effects of collagen and gleatin on the cyclooxygenase-2 (COX-2) gene which plays a crucial role in many physiological and pathological processes in macrophages. (omitted)
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