대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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- Pages.123.1-123.1
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- 2003
Relation of Chitosan oligosaccharide-induced Melanin Production to The Activity and Expression of Tyrosinase in B16 Melanoma Cells
- Yun, Yoon-Mi (College of Pharmacy, Chung-Ang University) ;
- Young, Cho-Nam (College of Pharmacy, Chung-Ang University) ;
- Kim, Kyung-Won (College of Pharmacy, Chung-Ang University) ;
- Lee, Ji-Yun (College of Pharmacy, Chung-Ang University) ;
- Kim, Chang-Jong (College of Pharmacy, Chung-Ang University) ;
- Soo, Sim-Sang (College of Pharmacy, Chung-Ang University)
- 발행 : 2003.10.01
초록
To investigate the effect of chitosn oligosaccharide on skin care, we measured tyrosinase activity and melanin production in B16 melanoma cells, and elastase and hyaluronidase activity. Chitosan oligosaccharide itself did not have any anti-oxidant activity in DPPH radical scavenging, and did not affect the proliferation of B16 melanoma cells. Chitosan oligosaccharide dose-depednetly increased mealnin production in the absence or presence of MSH. However, chitosan oligosaccharide did not have any influence on the tyrosinase activity and tyrosinase expression in B16 melanoma cells. (omitted)
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