Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2003.10b
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- Pages.170-170
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- 2003
Repeated Dose 4-week Oral Toxicokinetic Study of DW-224a in Rats
-
Lee, Jong-Hwa
(Korea Institute of Toxicology)
;
- Lee, Han-Ok (Korea Institute of Toxicology) ;
-
Chung, Moon-Koo
(Korea Institute of Toxicology)
;
- Park, Dong-Rack (Dong-Wha Pharm. Ind. Co., Ltd.) ;
- Gu, Se-Kwang (Dong-Wha Pharm. Ind. Co., Ltd.) ;
- Yasuo Tarumoto (Korea Institute of Toxicology) ;
- Shin, Ho-Chul (Korea Institute of Toxicology)
- Published : 2003.10.01
Abstract
DW -224a is a fluoroquinolone antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative bacteria. In order to clarify toxicokinetic profile of DW-224a, a 4-week repeated dose oral toxicokinetic study (dose level: 0, 63, 250, 1000 mg/kg) was conducted in groups of Sprague-Dawley rats.(omitted)