Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2002.11b
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- Pages.186-186
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- 2002
IN VITRO IMMUNOTOXICITY OF MBP, A MAJOR METABOLITE OF DI-N-BUTYL PHTHALATE(DBP) ON SD RAT SPLENIC B CELLS AND HUMAN B LYMPHOMA CELLS
- Juno H. Eom (Immunotoxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
- Chung, Seung-Tae (Immunotoxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
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Park, Jae-Hyun
(Immunotoxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration)
;
- Lee, Jong-Kwon (Immunotoxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
- Oh, Hae-Young (Immunotoxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration) ;
- Kim, Hyung-Soo (Immunotoxicology Division, National Institute of Toxicological Research, Korea Food and Drug Administration)
- Published : 2002.11.01
Abstract
Di-n-butyl phthalate(DBP) is one of the most commonly used phthalic acid esters(PAEs) as a plasticizer, a solvent or a component in cosmetic formulations. MBP(monobutyl phthalate) is a major metabolite of DBP. Although DBP has been identified as a reproductive toxicant in several animal species and also known as a endocrine disruptor, the direct or indirect immunomodulatory effect of DBP has been little reported.(omitted)