Proceedings of the Korean Society of Toxicology Conference (한국독성학회:학술대회논문집)
- 2002.11b
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- Pages.157-157
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- 2002
Acute and subacute toxicity studies of GX-12, a DNA vaccine for the treatment of HIV infection, in SD rats
- Park, Seul-Min (Research Laboratories, Dong-A Pharm. Co. Ltd.) ;
- Kang, Kyung-Koo (Research Laboratories, Dong-A Pharm. Co. Ltd.) ;
- Sohn, Yong-Sung (Research Laboratories, Dong-A Pharm. Co. Ltd.) ;
- Kim, Mi-Ju (Research Laboratories, Dong-A Pharm. Co. Ltd.) ;
- Baik, Dae-Hyun (Research Laboratories, Dong-A Pharm. Co. Ltd.) ;
-
Ahn, Byung-Ok
(Research Laboratories, Dong-A Pharm. Co. Ltd.)
;
- Kim, Won-Bae (Research Laboratories, Dong-A Pharm. Co. Ltd.)
- Published : 2002.11.01
Abstract
The toxicity of GX-12, a naked DNA vaccine developed by research team of Dong-A Pharmaceutical Company, Green Cross Company and Genexine for the treatment of HIV infection, was investigated in Sprague-Dawley rats. In single-dose intramuscular/oral acute toxicity studies, animals were treated 0, 250, 1000 or 4000