An Analysis on Treatment Schedule of Carbon Ion Therapy to Early Stage Lung Cancer

  • Sakata, Suoh (Hospital, Research Center of Charged Particle Therapy, National Institute of Radiological Sciences) ;
  • Miyamoto, Tadaaki (Hospital, Research Center of Charged Particle Therapy, National Institute of Radiological Sciences) ;
  • Tujii, Hirohiko (Hospital, Research Center of Charged Particle Therapy, National Institute of Radiological Sciences)
  • Published : 2002.09.01

Abstract

A total of 134 patients with stage 1 of non-small cell lung cancer treated by carbon ion beam of HIMAC NIRS were investigated for control rate and delivered dose. The delivered dose of every patient was converted to biological effective dose (BED) of LQ model using fraction number, dose per fraction and alpha beta ratio which shows the maximum correlation between BED and tumor control. The BED of every patient was classified to establish a BED response curve for control. Assuming fraction numbers, dose response curves were introduced from BED response curve. The total doses to realize several control rates were obtained for the treatment of small fraction number.

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