• 한국자기학회지
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• 제5권3호
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• pp.210-215
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• 1995

Glass\Cr/sub 40 .angs. /\[Cr/sub 10 .angs. /\NiFe/sub 50 .angs. /]/sub N/ 다층박막을 층수 N = 1, 2, 3, 4, 5, 6, 10에 따라 dc magnetron sputtering 방법에 의해 제작하였다. 이때 자기 이방성의 형성을 위해 제작 중에 자장을 200 Gauss 가했다. 전류 방향과 외부 자장이 수평, 수직에 따라 자기저항 곡선 MR(xx), MR(xy)를 조사하였다. MR(xx) 곡선의 경우 N = 1, 5, 10 경우 자기저항비가 거의 나타나지 않았으며, 나머지 층수의 경우는 외부 자장에 따라 저항이 증가하는 positive magnetoresistance 현상을 보였다. 또한 곡선의 모양도 H = 0 Oe 근처에서 특이하게 반전되는 자기정항 곡선을 보였다. 이런 현상의 물리적 해석을 NiFe 단층박막의 자기저항 곡선과 비교하여 설명 하였다.

• 제어로봇시스템학회논문지
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• 제9권7호
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• pp.507-514
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• 2003

Inspection and shape measurement of three-dimensional objects are widely needed in industries for quality monitoring and control. Recently the shape measurement using interferometric principle is found to be a successful methodology among other visual or optical technologies. Especially, the measuring method using wavelength scanning interferometer(WSI) has a great advantage in comparison with other conventional jnterferometric methods in that the absolute distance from the reference surface can be directly obtained from the amount of jnterferometric phase change. However, the measurement methods using WSI proposed by other researchers have low measurement resolution so far because they can't measure fractional phase change. To avoid this shortcoming we propose a new algorithm in this paper, which can obtain a small amount of even fractional phase change by sinusoidal function fitting. To evaluate the effectiveness of the proposed sinusoidal function fitting algorithm, a series of measuring experiments are conducted for discontinuously shaped specimens which have various height. The proposed algorithm shows much more enhanced measurement resolution than other existing conventional algorithms such as zero crossing algorithm and Fourier transform algorithm.

• 대한기계학회논문집
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• 제19권7호
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• pp.1630-1641
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• 1995

The dynamic stress intensity factors (DSIF ; $K_{I}$$^{dyn}$) were studied in some polymeric materials using caustics method with a high speed camera system. Also crack tip propagation speed was measured by dynamic crack propagation velocity measuring device. To calculate DSIF a finite element analysis program-INha Stress Analysis Moving CRack(INSAMCR) was utilized. Dynamic fracture characteristics were investigated to verify a relationship between DSIF and crack tip propagation speed and acceleration in PMMA, Homalite-100 and Polycarbonate. The relationship between dynamic stress intensity factor and crack tip velocity revealed typical shapes. Measured crack tip acceleration data envelope converges to the zero level with increasing DSIF. Equivalently crack tip velocities show a wide spread range at low values of DSIF, but become a constant with a higher DSIF. $1.2MPa{\sqrt{m}}$, $1.4MPa{\sqrt{m}}$ and $1.3 MPa{\sqrt{m}}$ were obtained as $K_{I}$$^{dyn}$ values to arrest the dynamic crack for PMMA, Homalite-100 and Polycarbonate, respectively. INSAMCR was run to verify experimental results in PMMA and shows good agreementment.

• Journal of Pharmaceutical Investigation
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• 제30권2호
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• pp.107-112
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• 2000

The changes in pharmacokinetic parameters of tolbutamide, such as the area under the plasma concentration-time curve from time zero to time infinity (AUC) and elimination rate constant (Kel) were evaluated after oral administration of the drug to rabbits with acute and chronic alloxan-induced diabetes mellitus (AIDRs). After oral administration, the plasma concentrations of tolbutamide were significantly higher between 9 and 12 hr in chronic AIDRs compared with these in control rabbits. Therefore, the AUC was significantly greater in chronic AIDRs $(3,490{\pm}649\;versus\;5,020{\pm}1,030{\mu}gml{\cdot}hr)$. This could be due to inhibition of tolbutamide metabolism by liver in AIDRs since tolbutamide is essentially completely metabolized in liver. Impaired liver and kidney function in AIDRs were based on blood chemistry and tissue microscopy. The absorption rate constant and Kel were significantly slower in chronic AIDRs compared with those in control rabbits.

• 한국자동차공학회논문집
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• 제13권4호
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• pp.58-65
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• 2005

A method measuring angular speed and estimating angular acceleration of an automotive wind shield wiper pivot with limited resources has been proposed. Limited resources refer to the fact that processes cannot be operated in real-time with a regular notebook running a Microsoft Windows. Also, they refer to the fact that data acquisition cards have only two general purpose counters as many generic cards do. An optical incremental encoder has been employed for measuring angular motion. To measure the angular speed of the pivot, periods for the encoder's output pulses have been measured as the speed is related to the reciprocal of the period. Since only information acquired from one counter channel is the magnitude of the angular speed, sign correction is necessary. Also the information for the exact time when a pivot passes left and right dead points is also missing and the situation is inherent to the hardware setup. To find out the zero-crossing time of the angular speed, a linear interpolation technique has been employed. Lastly, to overcome the imperfection of the mechanical encoders, the angular speed has been curve fitted to a spline. Angular acceleration can be obtained by a differentiation of the angular speed.

• Tribology and Lubricants
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• 제13권2호
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• pp.52-59
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• 1997

An experimental study is presented for the characteristics of the high temperature superconductor as an application of the repulsive type magnetic bearing. A ring shaped YBCO type superconductor and Neodium permanent magnets are employed for the experiment. For the case of field cooling, superconductor shows strong repulsive force, which is due to the Meissner effect, as the gap between the superconductor and the magnet gets closer. The repulsive force variation with respect to the gap change shows hysterisis characteristics. The area of the loop of the hysterisis curve represents the dissipation of energy, which reveals that the magnetic bearing with superconductor has large damping. The effect of the initial gap and the magnetic flux density on the repulsive force is analyzed experimentally and the static stiffness variation is calculated from the measured repulsive force variation. The relative sliding velocity between the superconductor and the magnet has little effect on the repulsive force which is quite different from the usual sliding element bearing. As the initial gap for the field cooling becomes larger, the maximum repulsive force at the minimum gap increases and approaches to the value for the case of zero field cooling.

• Biomolecules & Therapeutics
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• 제8권3호
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• pp.262-268
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• 2000

The bioequivalence of two tiropramide products was evaluated in 18 health male volunteers following oral administration. Test product was Tira $m^{R}$ tablet (Shin Poong SP-102) (Shin Poong Pharm. Co., Ltd.) and reference product was Tirop $a^{R}$ tablet (Dae Woong Pharm. Co., Ltd.) One capsule of the test and reference product containing 100 mg of tropramide.hydrochloride was administered to the volunteers by randomized two period cross-over study (2 $\times$ 2 Latin square method). The drug concentration in plasma was determined by GC/MS for over a period of 12hours after administration. Analysis of variance reveal that there are no differences in AUC (area under the plasma concentration-time curve from time zero to infinity), Cmax (maximum plasma concentration) and Tmax (time to reach Cmax). The differences of mean AUC, Cmax and Tmax between two products were 3.85, 1.47 and -3.6%, respectively. Minimum detectable differences (%) at $\alpha$=0.1 were all less than 20% given as a guideline (18.07, 17.00 and 20.69% for AUC, Cmax and Tmax, respectively). From these results, the two products are bioequivalent.ent.

• Archives of Pharmacal Research
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• 제27권7호
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• pp.693-712
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• 2004

The rats with protein-calorie malnutrition (PCM, 5％ casein diet for a period of 4-week) were reported to exhibit 60 and 80％ suppression in the hepatic microsomal cytochrome P450 (CYP) 1 A2 and CYP2C11 levels, respectively, and 40-50％ decreases in CYP2E1 and CYP3A 1/2 levels compared to control (23％ casein diet for a period of 4-week) based on Western blot analysis. In addition, Northern blot analysis showed that CYP1 A2, CYP2E1, CYP2C11, and CYP3A1/2 mRNAs decreased in the state of PCM as well. Hence, pharmacokinetic changes of the drugs in rats with PCM [especially the area under the plasma concentration-time curve from time zero to time infinity (AUC) changes of metabolite(s)] reported from literatures were tried to explain in terms of CYP isozyme changes in the rats. Otherwise, the time-averaged nonrenal clearance ($CL_{NR}$) of parent drug was compared. Pharmacokinetic changes of the drugs in other types of malnutritional state, such as kwashiorkor and marasmus, in both human and animal models were also compared. The drugs reviewed are as follows： diuretics, antibiotics, anticancer agents, antiepileptics, antiarrythmics, analgesics, xanthines, antimalarials, and miscellaneous.

• International Journal of Naval Architecture and Ocean Engineering
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• 제12권1호
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• pp.832-842
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• 2020

The coordination control of multiple Underactuated Underwater Vehicles (UUVs) moving in three dimensional space is investigated in this paper. The coordinated path following control task is decomposed into two sub tasks, that is, path following control and coordination control. In the spatial curve path following control task, path following error dynamics is build in the Serret-Frenet coordinate frame. The virtual reference object can be chosen freely on the desired spatial path. Considering the speed of the UUV, the line-of-sight navigation is introduced to help the path following errors quickly converge to zero. In the coordination control sub task, the communication topology of multiple UUVs is described by the graph theory. The speed of each UUV is adjusted to achieve the coordination. The path following system and the coordination control system are viewed as the feedback connection system. Input-to-state stable of the coordinated path following system can be proved by small gain theorem. The simulation experiments can further demonstrate the good performance of the control method.

• Tribology and Lubricants
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• 제37권3호
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• pp.112-116
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• 2021

Appropriate friction model usage is important for impact analysis because the relative motions between parts that are in contact for very short durations can vary greatly depending on the friction model. Vehicle seat components that have significant effects on impact analysis are also considered. This paper presents an experimental investigation of various material contact pairs to obtain the friction parameters of the Benson exponential friction model for impact simulation. The Coulomb friction model has limitations for impact analysis because of singularity at zero velocity. Metal/nonmetal materials are prepared, and friction tests are conducted for various sliding speeds, loads, and lubrication conditions. The obtained data are used in the friction model to implement finite element analysis. The parameters of the friction model are obtained by the curve-fitting method. The experimental results show that the friction coefficient with metal/nonmetal contact pairs is stable regardless of the working conditions. The friction model used in this study can also be applied for finite element analysis of the crash conditions, where the friction changes abruptly at the contact interface; the obtained friction parameters are also expected to be more accurate with more precise tests under different working conditions. These results can help improve the accuracy of the finite element analysis.