• 혜화의학회지
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• 제16권2호
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• pp.99-107
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• 2007

Keeping in step with four seasons, Spring, summer, autumn, and winter, the heaven and earth(天地) has been born(生), grown(長), coverted(化), gained(收), and kept(藏) by interaction of yiyang and yuqi(五氣: 木火土金水). And according to Naiching, human being is born with energy of heaven and earth(天地之氣) and is grown with the law of four seasons(四時之法). So, we now know that the human's body and nature interact each other. The oriental medical science has been studied the effect that the nature's change influences on human body. Now, I get some idea that using herb medicine and acupuncture should have hanged following the change of four seasons. We know that there is a cycle in nature. Every day sun arise and down, and every month moon gets full and new. And every year, four seasons orderly change, from spring to winter. All of this is the law of nature and human body adapts this law. Man always shows the physiological phenomena which changes under the law of nature, especially the turning of the seasons. Therefore, we should use different medical methods in different seasons.

• 한국수학교육학회지시리즈B:순수및응용수학
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• 제21권1호
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• pp.77-93
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• 2014

This paper focuses on computational contractual distinctions as an explanation for the spread between a forward contract and a similar futures contract which is derived and investigated. We evaluate this spread by constructing a time series model, which was established based on copula functions, and also show that the forward-futures spread is more significant for long maturity.

• Journal of Power Electronics
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• 제19권4호
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• pp.956-967
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• 2019

This paper introduces a virtual signal injected maximum torque per ampere (MTPA) control strategy for direct-torque-controlled five-phase interior permanent magnet synchronous motor (IPMSM) drives. The key of the proposed method is that a high frequency signal is injected virtually into the stator flux linkage. Then the responding stator current is calculated and regulated to compensate the amplitude of the flux linkage. This is done according to the relationship between the stator current and the stator flux linkage. Since the proposed method does not inject any real signals into the motor, it does not cause any of the problems associated with high-frequency signals, such as additional copper loss and extra torque ripple. Simulation and experimental results are offered to verify the effectiveness of the proposed method.

• 한국융합학회논문지
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• 제11권4호
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• pp.17-25
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• 2020

본 연구는 식당에서 사용하는 외식서빙 로봇의 서비스 절차 및 인터랙션 방식에 중점을 두고 연구한다. 사용자 설문조사,사용자를 관찰하고 고객과 레스토랑 종업원의 인터뷰를 통한 레스토랑 서빙 로봇과 고객의 교류방식을 분석하고 사용자 요구를 파악하기 위해 사용자 여정 지도를 구축한다. 또한 서비스 절차에서 배달 서비스 뿐만 아니라 주문 서비스, 접대 서비스 및 테이블 정리 등을 모두 서비스 로봇이 행하는 것을 의도한다.최종 제안 연구 목적은 기존의 서빙 로봇 GUI을 개선하고 새로운 서비스 청사진을 설계하는 것이다.

• 한국결정성장학회지
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• 제4권3호
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• pp.230-237
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• 1994

본 논문은LBO 결정성장 및 응용과 높은 점성을 갖는 용액에서 결정성장의 열역학과 동역학의 모델에 관하여 연구하였다. 결정공명과 press-controlled oscillator의 특성에 대한 측정은 이러한 종류의 결정이 많은 응용 가능서을 갖는 압전 결정재료의 한 종류임을 나타내 준다.

• BMB Reports
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• 제47권5호
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• pp.256-261
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• 2014

To investigate the function of N-glycosylation of Cel5A (endoglucanase II) from Hypocrea jecorina, two N-glycosylation site deletion Cel5A mutants (rN124D and rN124H) were expressed in Saccharomyces cerevisiae. The weights of these recombinant mutants were 54 kDa, which were lower than that of rCel5A. This result was expected to be attributed to deglycosylation. The enzyme activity of rN124H was greatly reduced to 60.6% compared with rCel5A, whereas rN124D showed slightly lower activity (10%) than that of rCel5A. rN124D and rN124H showed different thermal stabilities compared with the glycosylated rCel5A, especially at lower pH value. Thermal stabilities were reduced and improved for rN124D and rN124H, respectively. Circular dichroism spectroscopy showed that the modification of secondary structure by mutation may be the reason for the change in enzymatic activity and thermal stability.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제15권9호
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• pp.3204-3220
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• 2021

We perform the task of video object segmentation by incorporating a conditional random field (CRF) and convolutional neural networks (CNNs). Most methods employ a CRF to refine a coarse output from fully convolutional networks. Others treat the inference process of the CRF as a recurrent neural network and then combine CNNs and the CRF into an end-to-end model for video object segmentation. In contrast to these methods, we propose a novel higher-order CRF model to solve the problem of video object segmentation. Specifically, we use CNNs to establish a higher-order dependence among pixels, and this dependence can provide critical global information for a segmentation model to enhance the global consistency of segmentation. In general, the optimization of the higher-order energy is extremely difficult. To make the problem tractable, we decompose the higher-order energy into two parts by utilizing auxiliary variables and then solve it by using an iterative process. We conduct quantitative and qualitative analyses on multiple datasets, and the proposed method achieves competitive results.

• Journal of Power Electronics
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• 제19권2호
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• pp.380-393
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• 2019

Traditional boost converters have difficulty realizing high efficiency and high voltage gain conversion due to 1) extremely large duty cycles, 2) high voltage and current stresses on devices, and 3) low conversion efficiency. Therefore, a function decoupling high voltage gain DC/DC converter composed of a DC transformer (DCX) and an auxiliary converter is proposed. The role of DCX is to realize fixed gain conversion with high efficiency, whereas the role of the auxiliary converter is to regulate the output voltage. In this study, different forms of combined high voltage gain converters are compared and analyzed, and a structure is selected for the function decoupling high voltage gain converter. Then, topologies and control strategies for the DCX and auxiliary converter are discussed. On the basis of the discussion, an optimal design method for circuit parameters is proposed, and design procedures for the DCX are described in detail. Finally, a 400 W experimental prototype based on the proposed optimal design method is built to verify the accuracy of the theoretical analysis. The measured maximum conversion efficiency at rated power is 95.56%.

• Journal of Microbiology and Biotechnology
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• 제31권5호
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• pp.740-746
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• 2021

Efficient cellulolytic enzyme production is important for the development of lignocellulose-degrading enzyme mixtures. However, purification of cellulases from their native hosts is time- and labor-consuming. In this study, a constitutive expression system was developed in Penicillium oxalicum for the secreted production of proteins. Using a constitutive polyubiquitin gene promoter and cultivating with glucose as the sole carbon source, nine cellulolytic enzymes of different origins with relatively high purity were produced within 48 h. When supplemented to a commercial cellulase preparation, cellobiohydrolase I from P. funiculosum and cellobiohydrolase II from Talaromyces verruculosus showed remarkable enhancing effects on the hydrolysis of steam-exploded corn stover. Additionally, a synergistic effect was observed for these two cellobiohydrolases during the hydrolysis. Taken together, the constitutive expression system provides a convenient tool for the production of cellulolytic enzymes, which is expected to be useful in the development of highly efficient lignocellulose-degrading enzyme mixtures.

• Journal of Microbiology and Biotechnology
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• 제32권12호
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• pp.1506-1514
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• 2022

Allergic contact dermatitis (ACD) is an allergen-specific T-cell-mediated inflammatory response, albeit with unclear pathogenesis. Exosomes are nanoscale extracellular vesicles secreted by several cell types and widely distributed in various biological fluids. Exosomes affect the occurrence and development of ACD through immunoregulation among other ways. Nevertheless, the role of exosomes in ACD warrants further clarification. This review examines the progress of research into exosomes and their involvement in the pathogenesis, diagnosis, and treatment of ACD and provides ideas for exploring new diagnostic and treatment methods for this disease.