• Title/Summary/Keyword: young-old

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Body Height Effect on Brain Volumes in Youth Decreases in Old Age in Koreans

  • Koh, In-Song
    • Interdisciplinary Bio Central
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    • v.3 no.3
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    • pp.11.1-11.5
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    • 2011
  • The MRI (magnetic resonance imaging) volumetric analysis of the brain was performed in 59 healthy elderly Koreans (aged 62-76 years; 34 male, 25 female) to investigate whether the previously reported significant correlations between body height and brain volumes in the young aged Koreans (20's) still exist in the old aged Koreans (60's and 70's). Unlike previously reported significant correlations in the young aged Koreans, neither the correlation between whole brain volume and body height in male nor the correlation between cerebellar volume and body height in female show any significance in the old aged Koreans. The significant correlation between body height and whole brain volume was still observed when both male and female data were combined (r=0.27, P<0.05), but the correlation coef-ficient and the level of significance markedly decreased from those of previously reported Korean youth data (r=0.67, P<0.01). Simple linear regression analysis shows decrease of explanatory power of height (measured in $r^2$) from 44% in the youth group to 7% in the old age group on the variance of whole brain volume. Multiple linear regression analysis shows that age and sex, rather than height, are major explanatory variables for whole brain volume in the old aged Koreans. The loss of correlations in the aged group is suspected to be mainly due to age related brain volume changes.

No Late Effect of Ionizing Radiation on the Aging-Related Oxidative Changes in the Mouse Brain

  • Jang, Beom-Su;Kim, Seolwha;Jung, Uhee;Jo, Sung-Kee
    • Journal of Radiation Industry
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    • v.4 no.3
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    • pp.203-207
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    • 2010
  • Radiation-induced late injury to normal tissue is a primary area of radiation biology research. The present study was undertaken to investigate whether the late effect of the ionizing radiation appears as an age-related oxidative status in the brain. Three groups of 4-month old C57BL/6 mice that were exposed to $^{137}Cs$ ${\gamma}-rays$ at a single dose (5 Gy) or fractionated doses ($1Gy{\times}5times$, or $0.2Gy{\times}25times$) at 2 months old were investigated for the oxidative status of their brains with both young (2-month) and old (24-month) mice. A significant (p<0.05) decrease in superoxide dismutase (SOD) activity was observed in old mice brains compared with that of the young mice. malondialdehyde (MDA) content was significantly (p<0.05) increased in the old mice brain. However, any significant difference in SOD activity and MDA contents of the irradiated brain was not observed compared to age-matched control group mice. SOD activity and MDA content were observed within good parameters of brain aging and there were no late effects on the age-related oxidative level in the ${\gamma}-ray$ irradiated mice brains.

Effect of Plant Age on Infection of Soybean by Calonectria ilicicola (Calonectria ilicicola의 감염에 대한 콩 식물체 나이가 미치는 영향)

  • ;J. S. Russi;J. P. Snow
    • Korean Journal Plant Pathology
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    • v.14 no.3
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    • pp.247-252
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    • 1998
  • A series of greenhouse test was conducted to evaluate infection of Calonectria ilicicola on soybean plants of different ages at time of inoculation. Lesion length and number of perithecia were determined on cultivars Braxton, Deltapine 726, and Riverside 699 that were 10∼40 days old and 4-10 days old at time of inoculation. Quadratic and linear relationships were described between plant age at inoculation and lesion length or perithecia production in greenhouse studies. Soybean seedlings exhibited low susceptibility to C. ilicicola regardless of cultivar susceptibility. On 8- or 1-0-days-old Braxton, lesion lenght and perithecia numbers were reduced. Lesion lengths were longest on plants 30 days old whereas perithecia production was greatest on plants 20∼30 days old at time of inoculation. Differences in lesion length and perithecia production that were observed on young plants (4∼10 days old) were similar to relative levels of susceptibility in soybean cultivars in greenhouse and field tests, suggesting that reaction to C. ilicicola in soybean cultivars may be determined early in plant development.

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Formation and Change of Road·Block·Lot System of Old Inner Cheongju City (청주 구도심 지역의 가로·가구·필지체계의 형성과 변천)

  • Weon, Se-Yong;Kim, Tai-Young
    • Journal of the Korean Institute of Rural Architecture
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    • v.5 no.2
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    • pp.10-19
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    • 2003
  • The purpose of this study was to analyze the formation and change of road-block-lot of the old inner city in cheongju The result of this study are as follows; (I)Among others a system roads of in around the old castle in cheongju city is most of feature north and south direction of road. Lot system is organic relations of north and south direction of road. Therefore, urban tissue in around the old castle in cheongju city is established order road system keep on the change of expansion urban tissue. (2) Block type classified into non-division, 2division and over 3division. (3) The square block remains mostly in Cheongju old castle, two-division block was around south of castle. And block of the grid-form street system divided into over 3 division. Through the guideline about characteristic of block type, residential area should be developed as a characteristics area in the urban area.

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The Effect on the Life Satisfaction of the Korean Elderly according to Their Preparation for Old Ages - Focusing on the Mediating Effects of Productive Activities - (노후준비도가 노인의 생활만족도에 미치는 영향 연구 -생산적 활동의 매개효과-)

  • Hong, Young Joon;Lee, Jung-Hoon
    • Journal of Family Resource Management and Policy Review
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    • v.18 no.4
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    • pp.91-110
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    • 2014
  • The purpose of this study is to examine the effect of preparation for old age on the life satisfaction, and the mediating effect of productive activities on the relationship between preparation for old and life satisfaction among the old age in Korea. The subject for this study is 226 older adults who participated in the work fare program of community welfare centers. The collected data were analyzed with SPSS WIN(ver.18.0) program, and frequency analysis, descriptive analysis, multiple regression, and Sobel test were utilized. The result revealed that productive activities has a partial mediating effect between preparation for old Age and life satisfaction. Based on these findings, the theoretical and practical implications were discussed.

The Effectiveness of a Proposed VR Model as a Method to Relieve Distress and Improve Communication during Pediatric Dental Treatment in 3-9 Year-Old Children

  • Aalqeel, Samia;Song, Eun-Jee
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2022.05a
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    • pp.577-578
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    • 2022
  • This study addresses the effectiveness of a VR model that is designed to relieve distress and improve communication during pediatric dental treatment for 3-9 year-old young patients. This is due to the challenging nature of the dental treatment for both young patients and pediatric dentists. The proposed model is designed to alleviate the unpleasant experience a young patient might go through during the dental treatment through providing a VR content to be displayed in on a head-mounted device during the treatment session. In addition, the model is designed to help decrease the frequent movement of the young patient during the dental treatment session by directing the patient's head to the immersive VR content. Furthermore, the model could solve the communication difficulties that might occur between pediatric dentists and young patients during the treatment session by showing live instructions related to adjusting body postures

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Changes in the Growth of Young Rice Seedlings in the Root Extension Stage under Different Growth Conditions (벼 착근기 생육 환경에 따른 어린모의 생육변화 분석)

  • Choi, Myoung Goo;Jeong, Jae-Hyeok;Lee, Hyen-Seok;Yang, Seo-Yeong;Lee, Chung-gun;Hwang, Woon-Ha
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.65 no.3
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    • pp.192-198
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    • 2020
  • Root extension is the most important growth change that occurs during cultivation. We analyzed growth changes according to young seedling age, temperature, and the degree of root cutting in order to identify factors affecting rooting after transplanting. Root cutting did not affect plant height growth rate, root growth rate was increased in plants that experienced root cutting, and 14-day-old seedlings exhibited a higher growth rate than 7-day-old seedlings. Growth temperature experiments revealed that elongation was high at 25℃ and 28℃, but tended to be low at 18℃, and root elongation was high at 22-28℃ for 7-day-old seedlings and 22-25℃ for 14-day-old seedlings. Nitrogen absorption decreased in the following growth temperature order: 25, 28, 22, 18℃, and differences in nitrogen absorption under different growth temperatures tended to be lower in 7-day-old seedlings. The amount of nitrogen taken up by roots did not differ significantly between the short root treatment and the control, and 7-day-old seedlings tended to start nitrogen absorption faster than 14-day-old seedlings. Root vitality was highest in short-rooted 7-day-old seedlings with 3 cm of root remaining, and vitality also tended to be high in short-rooted 14-day-old seedlings.

Changes in 3-Butenyl Isothiocyanate and Total Glucosinolates of Seeds and Young Seedlings during Growth of Korean Chinese Cabbages (배추 종자 및 어린 싹의 성장 시기에 따른 3-butenyl isothiocyanate 및 total glucosinolates 함량 변화)

  • 김연경;김건희
    • Food Science and Preservation
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    • v.10 no.3
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    • pp.365-369
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    • 2003
  • The main objective of this study was to investigate the pattern of glucosinolates, in terms of 3-butenyl isothiocyanate, and total glucosinolates, in different parts of young seedlings and seeds in Korean Chinese cabbages. For determination of glucosinolates, 55 days and Winter pride cultivars of Korean Chinese cabbages seeds and different parts of 1, 3, 5, and 7-day-old seedlings were used for analytical sample preparation provided with an anion exchanges column, and measured by GC and UV-visible Spectrophotometer. The concentration of 3-butenyl ITC was higher in the cotyledon and the hypocotyl parts of 55 days cultivar seedling than those of Winter Pride cultivar. In the cotyledon parts of Winter pride cultivar seedling, 3-butenyl ITC amount was increase to 3-day-old seedling and then reduced. The cotyledon of 55 days cultivar contained the highest concentration of total glucosinolates while those were increased in the hypocotyl and decreased in the root. The level of total glucosinolates was increased to 5-day-old seedling and then decreased in the cotyledon and the hypocotyl parts of seedling in Winter pride cultivar. There was no significant difference of total glucosinolates in the root part. In the seeds, 55 days cultivar concentration was higher than Winter pride cultivar both of 3-butenyl ITC and total glucosinolates. In our study, the levels of 3-butenyl ITC and total glucosinolates depended on cultivars, growth stages, and parts in Korean Chinese cabbage.

In vitro Effects of L-Ascorbic Acid and Acrylamide on Lymphocyte Proliferation in Young and Aged Mice

  • Kang, Nam-Sung;Pyo, Suhk-Neung;Sohn, Eun-Hwa
    • Preventive Nutrition and Food Science
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    • v.15 no.1
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    • pp.19-23
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    • 2010
  • This study examined the effects of Acrylamide (ACR) and L-ascorbic acid (AsA) on the proliferation of splenocytes and the mitogen-stimulated lymphocyte proliferation in young (8 weeks) and aged (82 weeks) C57BL/6male mice in vitro. AsA increased splenocyte proliferation in both groups; however, this effect was higher in old mice, while the proliferation of lymphocyte was decreased except for treatment at $1\;{\mu}g/mL$ low concentration in both mice. In addition, ACR treatment resulted in decreased LPS-induced B lymphocyte proliferation and ConA-induced T lymphocyte proliferation in both groups. However, AsA increased LPS/ConA-induced lymphocyte proliferation in young groups and had no effects in old mice except at $0.5\;{\mu}g/mL$ Thus, the present data indicate that there is no difference effect of ACR and AsA on lymphocyte proliferation, whereas the effect of AsA on mitogen-induced cell proliferation was reduced in old mice. Overall, our results suggest that various immunomodulators have differing effects of lymphocytic proliferation on young versus aged mice.

Comparative Study of Durability of Bioprosthetic Valve Considering Age of Patients (Ionescue-Shiley 조직판막의 환자 연령군에 따른 내구성에 관한 비교연)

  • 김진국
    • Journal of Chest Surgery
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    • v.20 no.4
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    • pp.673-682
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    • 1987
  • The principal feature of bioprosthetic valve which remains to be completely defined is long-term durability, especially, with regard to the impact of patient age. This report provides extended data regarding valve durability derived from a data base of 515 patients who received lonescu-Shiley bioprosthetic valve between 1978 and 1985; cumulative duration of follow-up was 1562.3 patient-years, with a maximum follow-up duration of 8.7 years. The results of this survey showed as follows: 1] The actuarial freedom from valve failure at 6 years were 43*7% for 0-19 year-old group, 70*1% for 20-39 year-old group and 75*1% for over 40 year-old group separately. 2] Of the causes of valve failure, only the primary tissue failure was markedly influenced by patient`s age [p<0.001], but the prosthetic valve endocarditis was not [p>0.1]. 3] The linealized incidences of primary tissue failure were 7.31% per patient-year in 0-19 year-old group and 0.12% in 20-39 year-old group. 4] The primary tissue failure rate in 0-19 year-old group was 6.36% during first 4 years, but then increased upto 10.95% at postoperative 5 year. Thus we find that in bioprosthetic valve the primary tissue failure is apt to occur when patient is young [especially less than 20 years old] and the postreplacement time passes [especially over 5 years]. The rate of bioprosthesis failure among children and adolescents is clearly higher than that observed in adult patients; however, conclusive quantification of time-related risk for young patient is not yet possible on the basis of existing data. Therefore, the advisability of bioprosthesis implantation in children remains to be determined.

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