• 한국지역사회생활과학회지
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• 제27권2호
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• pp.199-209
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• 2016

This study examined the mediating effects of emotional intelligence on the relationship between mothers' attachments to young children and the creative personality of the children. Pearson's correlations between variables were analyzed, and hierarchical regression analyses were conducted to identify the direct and indirect effects of a mothers' attachments to young children and the emotional intelligence and creative personality of the children. The sample included a total of 228 children aged 4-5 who were attending nursery in Gwangju, Korea. Significant differences were observed by gender and age, but no significant differences were found to be associated with the mother's attachment to the child by age. However, emotional intelligence partially mediated the relationships between the mother's attachment to the child and the child's creative personality. The results suggest that emotional intelligence may edify the creative personality of young child as a mediating response to the mother's attachment.

• 아동학회지
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• 제6권2호
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• pp.59-71
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• 1985

The purpose of this study was to analyze the effects of both social-status and mode of stimulus-presentation on children's empathic behavior, where empathy is defined as either the comprehension and recognition of an affective state in stimulus persons (others) or the empathic response to that perception. Middle-and lower-class kindergarten children were presented with a series of either short-sentence stories or short-pictorial stories. The subjects were asked to indicate how the child in each situation felt by selecting a "happy", "sad", or "angry" face to complete the picture accompanying each story. Immediately following the first question, children were asked to state verbally how the child in the picture might feel. The main results were (1) The mean empathy scores for the comprehension and recognition of an affective state in others and the empathic response to that perception was higher in middle-class children than in lower-class children. (2) There were differences in empathy scores to the three affective situations, i.e. the mean score for both happiness and sadness was significantly greater than for aggression, and (3) The empathy scores in the pictorial-stories were greater than in the sentence-stories.

• 아동학회지
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• 제2권
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• pp.31-39
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• 1981

Despite evidence from adults that stimulus incongruity increased arousal level, there have been no published reports demonstrating this relationship with children. Therefore, the present study was done to 1) investigate the relationship between the introduction of stimulus incongruity and children's arousal level, using the GSR as an index of arousal; 2) determine whether age difference among subjects would affect the magnitude of the effect of incongruity on GSR ; and 3) determine the feasility of using the GSR with young children, particularly when manipulating a variable considered to involve only modest increase in arousal. The results were: 1) The incongrous outcome of two brief stories increased the arousal level of the subjects in the present study 2) The effect was related primarily in the GSR arousal scores of adult subjects. The smaller or nonexistent reactions to incongruity by the children represent essentially new results, as little or previous research exists involving the arousal level of young children to visual or auditorily presented stimuli. Several possibilities regarding the failure of the incongruity to generate arousal in the young children were considered Methodolog both in using GSR as an index of arousal level and in developing visual or audio stimuli involving incongruity was discussed.

• Clinical and Experimental Pediatrics
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• 제62권7호
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• pp.274-280
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• 2019

Purpose: To analyze the growth response to growth hormone (GH) therapy in prepubertal patients with Noonan syndrome (NS) harboring different genetic mutations. Methods: Twenty-three patients with prepubertal NS treated at Pusan National University Children's Hospital between March 2009 and July 2017 were enrolled. According to the disease-causing genes identified, the patients with NS were divided into 4 groups. Three groups were positive for mutations of the PTPN11, RAF1, and SOS1 genes. The five genes undetected (FGU) group was negative for PTPN11, RAF1, SOS1, KRAS, and BRAF gene mutations. The influence of genotype was retrospectively analyzed by comparing the growth parameters after GH therapy. Results: The mean chronological age at the start of GH treatment was $5.85{\pm}2.67years$. At the beginning of the GH treatment, the height standard deviation score (SDS), growth velocity (GV), and lower levels of insulin-like growth factor-1 (IGF)-1 levels were not statistically different among the groups. All the 23 NS patients had significantly increased height SDS and serum IGF-1 level during the 3 years of treatment. GV was highest during the first year of treatment. During the 3 years of GH therapy, the PTPN11, RAF1, and SOS1 groups showed less improvement in height SDS, IGF-1 SDS, and GV, and less increase in bone age-to-chronological age ratio than the FGU group. Conclusion: The 3-year GH therapy in the 23 prepubertal patients with NS was effective in improving height SDS, GV, and serum IGF-1 levels. The FGU group showed a better response to recombinant human GH therapy than the PTPN11, RAF1, and SOS1 groups.

• Perspectives in Nursing Science
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• 제11권2호
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• pp.144-152
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• 2014

Purpose: The purpose of the study is to offer necessary data to develop nursing interventions to reduce intravenous injection pain and uneasiness among hospitalized children. Methods: A total of 200 patients aged 1-72 months were selected. Pain during intravenous cannulation was assessed using the Procedural Behavior Checklist (PBCL) and the Faces Pain Rating Scale (FPRS). Data were analyzed by t-test and ANOVA using the SPSS/WIN 12.0. Results: Younger patients showed higher pain response than older patients (F=33.87, p<.001). Children with respiratory diseases showed higher responses in FPRS and PBCL than children without respiratory disease (F=4.17, p=.017; F=25.31, p<.001, respectively). Children of preschool age showed higher pain response during IV cannulation than the comparison group (t=2.04, p=.045). Children who had previous experiences with hospitalization and injections showed higher response to pain than those without these experiences (t=2.05, p=.045). In regards to FPRS, patients who were recannulated showed more painful restarts compared with patients injected just once (t=-3.60, p<.001). In regards to PBCL, infants and toddlers (t=-4.88, p<.001) and preschoolers (t=-3.86, p<.001) showed high pain scores during recannulation. Conclusion: A sick child's response to pain may be worse as they feel more pain over time. These characteristics should be considered for development of nursing interventions.

• Molecules and Cells
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• 제43권2호
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• pp.99-106
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• 2020

Cells are constantly exposed to endogenous and exogenous stresses that can result in DNA damage. In response, they have evolved complex pathways to maintain genomic integrity. RUNX family transcription factors (RUNX1, RUNX2, and RUNX3 in mammals) are master regulators of development and differentiation, and are frequently dysregulated in cancer. A growing body of research also implicates RUNX proteins as regulators of the DNA damage response, often acting in conjunction with the p53 and Fanconi anemia pathways. In this review, we discuss the functional role and mechanisms involved in RUNX factor mediated response to DNA damage and other cellular stresses. We highlight the impact of these new findings on our understanding of cancer predisposition associated with RUNX factor dysregulation and their implications for designing novel approaches to prevent cancer formation in affected individuals.

• 아동학회지
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• 제9권2호
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• pp.29-59
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• 1988

Empathy was defined in this study as the vicarious affective response of a person to the perceived experience of another. The purpose of this study was to study the relationship between empathic development of children and intimacy with parents, socio-economic status, and children's empathic response to specific affective situations happy, sad, angry and fearful. The subjects for this study were 8-, 10-, and 12-year-old children attending an elementary school located in Seoul. Among the subjects, 158 boys and 149 girls lived with their parents, and 20 boys and 35 girls were reared in orphanges. They were from a residential area with higher, middle, and lower class families. The instruments consisted of two modified empathy measures and two questionnaires developed by the researcher. One of the empathy measures was based on Feshbach & Roe's affective situation test for empathy. In order to determine the eight themes, 20 children were interviewed individually about situations that made them "happy, sad, angry, and afraid". From the pool of responses, eight themes representing happy, sad, angry and fearful situations were selected. Each story consisted of a series of three pictures accompanying narration. Another modified empathy measure was developed by the researcher based upon Bryant's empathy scale. This measure consisted of 17 statements describing happy, sad, angry and fearful situations. The items in this scale were selected from a pilot study. The two questionnaires developed by the researcher were to test children's intimacy for their parents and feminity. The data was analyzed with T-test and F-test. Children's intimacy with their parents, particularly, son's intimacy with their mothers, was a significant variable in empathic development. Children living with their parents had higher scores on Feshbach & Roe's Empathy Test than those brought up in orphanages. In general, the older the children the higher the empathy score. Girls were more empathic than boys on Bryant's scale. The subjects showed their highest empathy score in the sad, and the lowest in the fearful situation. The older the children the higher the empathy score in the sad and angry situations. These results reflected children's life experiences and cultural differences. Particularly, mother-son intimacy found in this study contrasts with the mother-daughter intimacy found in American studies.

• 아동학회지
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• 제33권5호
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• pp.117-137
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• 2012

The purpose of this study was to analyze 5'year' old children's responses in the process of reading picturebooks on sexual abuse and to explore the educational implications of the results. 42'five year' old children and 2 of their teachers participated as subjects in the study. Data was collected by means of observation, a diary record of the teacher's class, and an interview with teachers about children's responses in the process of reading picturebooks on sexual abuse during the free choice activities, and group activities in J and K daycare centers in Busan, Korea from July to September. The results were as follows : the analysis identified three patterns of responses; consistent responses, awkward responses, and confused and frightened responses. These result imply that selecting picturebooks for sexual abuse preventive education programs for young children needs to be given careful consideration. The importance of the teacher's reading skills and sociocultural cognition regarding sexuality in general were also discussed.

• Child Health Nursing Research
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• 제22권1호
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• pp.21-28
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• 2016

Purpose: The purpose of this study was to identify effects of EMLA (Eutectic Mixture of Local Anesthetics) cream application on pain perception and pain response during insertion of implanted venous access port needle in children with cancer. Methods: From December 2010 to August 2011, at U university hospital, 20 patients scheduled for implanted venous access port needle insertion were recruited, and randomly assigned to receive either EMLA or a placebo cream 1 hour before the implanted venous access port needle insertion. While conducting needle insertion, changes in pulse and oxygen saturation on the pulse oxymeter monitor were measured and pain behavior reaction was also measured during needle insertion in the treatment room. After conducting needle insertion, self-reported pain reaction, and mothers' perception of the children's pain reaction were measured. Collected data were statistically processed using SPSS version 17.0 for Windows, and analyzed using descriptive statistics, t-test. Results: Children's self-reported degree of pain, degree of pain as perceived by mothers and pain behavior reaction decreased significantly in the EMLA application group compared with the placebo group. Conclusion: Findings indicate that application of EMLA cream is effective in relieving pain in these children during implanted venous access port needle insertion.

• 아동학회지
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• 제18권2호
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• pp.191-211
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• 1997

This study investigated the characteristics of children perceived as difficult by their mothers and compared these characteristics with the "difficult temperament" from the NYLS. The subjects were 36 mothers who have more than one child between 3 and 6 years of age. The descriptions from in-depth interviews were analyzed qualitatively. The results showed that (1) Korean mothers perceived the difficult temperament of their child as low adaptability, low rhythmicity in sleep habits, negative mood, and high activity. High response sensitivity was perceived as both a positive and a difficult characteristic. (2) The temperament of their children mothers perceived as most difficult for child rearing were negative mood and low manageability. (3) The activity, adaptability, rhythmicity, response sensitivity, mood and manageability characteristics of Korean children's difficult temperament was different from the difficult temperament of the Nyls.