• Journal of the Korean Society for Precision Engineering
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• v.3 no.3
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• pp.40-71
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• 1986

By developing a computer program for the systematic design of worm gears, the design formulae and tables of AGMA, JGMA, BS and DIN are analized and compared. The computer program can be used on micro-computers. According to the input data of the reduction ratio, the center distance. the driving torque and the material as design parameters, the program calculate the most efficient worm gear dimension. The variation of the design parameters and other empirical coefficients in case of resulting an inadequate design gear dimension can be easily modified throuth the way of interactive method between the user and the monitoring system of computer. A proposal of the standardization of worm gears was made in which a standard module according to the DIN 323 standard series number was applied. For the more exact and effective calculation of the stress concentration and the deformation of gear teeth, a computer program using the boundary element method is also developed. Even the strength of the special gear shape such as Niemann's "Cavex" gear can be calculated in a short CPU-time. The most effort of this study has been layed on the developing a computer program for the correction of a tooth profile and face width which is most important design factor for an exact and wide teeth contacts under loads, especially by great and wide gears. For this purpose were investigated the tooth stiffness, the mesh interferences and the kinematics and the dynamics of gear mesh. The deflection and the deformation of the gear shaft due to the loads acting on gear and shaft were aslo considered. Some examples have shown the sufficient good status of teeth contact in which the correction of the tooth profile and face width were accomplished due to the calculated results.d results.

• Development and Reproduction
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• v.23 no.3
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• pp.199-211
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• 2019

The sterilization effects of methylene blue (MB), formalin, and iodine on the egg of marine medaka, Oryzias dancena, were investigated for disinfecting naididae worm, Chaetogaster diastrophus through sterilization. To determine harmfulness of MB, formalin, and iodine, lethal concentrations 50 ($LC_{50}$) of three chemicals were analyzed in the eggs of marine medaka. The sterilized periods of each chemical were set at 1 hr. Sterilized rates of naididae worm in each chemical were significantly affected and increased drastically as the concentration of each chemical increased (p<0.05). Sterilization abilities of naididae worm were most effective for formalin, but survival rates of egg and hatched rates for formalin were lowest among each chemical. The $LC_{50}$ of MB over 96 hrs were 185.26, 103.84, and 127.15 ppm for adults, juveniles, and eggs respectively. The toxic effects of MB were clearly dose dependent for each life stage (p<0.05). The toxicity sensitivity of juveniles to MB was dramatically higher than that of other groups. In 48 hrs after sterilization, cortisol and glucose concentrations of the adult group with MB treatment were significantly higher than those of the adult group with no treatment (p<0.05). This research provides useful data on sterilization effect of MB, formalin, and iodine, acute toxicity in marine medaka egg and toxicity, sensitivity of life stage of MB in marine medaka.

• Applied Biological Chemistry
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• v.15 no.2
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• pp.163-168
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• 1972

Previously identified female pupae were X-irradiated with a dose of 1000r one day prior to moth transformation. Female mothes from irradiated and non-irradiated pupae were copulated with normal male ones and allowed to lay eggs. Fertilized eggs were collected at 6 intervals such as 5, 15, 45, 90 minutes, 12 and 40 hours after laying, and deep-freezed immediately after each collection until measurements. RNase activity and nucleic acid content were determined with each sample and following results were obtained. 1) It was proved to exist two RNases in silk worm eggs as in mammalian tissues, one active maximally at pH 5.8 and the other at pH 8.0, and the acid RNase activity was much higher than that of alkaline RNase. 2) The activity of acid and alkaline RNases increased remarkably during early development of the embryo of silk worm eggs, reaching the maximum activity at 45 minutes from laying time in non-irradiated group. There was no appreciable difference in two RNase activities for 45 minutes after laying in both control and irradiated groups, but the activity of acid and alkaline RNases in latter group was three times as much as that in former group, at 90 minutes from laying time and it was also found the acid RNase activity was 1.8 times higher than alkaline one in irradiated group. 3) The RNA-P content of control group increased considerably for initial 45 minutes, followed by a decline 45 minutes later with sight but steady increase thereafter. The RNA-P content of irradiated group, however, increased at initial 5 minutes, followed by a marked fall 90 minutes after laying, with no change thereafter. The DNA-P of control group showed a sharp increase for initial 45 minutes, followed by a decline 45 minutes later with no appreciable change thereafter, whereas that of irradiated group showed an increase at initial 15 minutes, followed by a sharp decline for following 45 minutes with a gradual increase thereafter. It was thus proved that the synthesis of nucleic acid in silk worm eggs was much suppressed by X-irradiation during early development of embryo. 4) The RNase activity varied in parallel with the RNA-P content in control group, but the RNA-P content in irradiated group was shown to be minimum value in concidence with the maximum activity of both RNases.

• Journal of the Korean Society for Precision Engineering
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• v.22 no.3 s.168
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• pp.162-169
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• 2005

The functional external fixator system fur bone deformity near joints in legs using the worm gear was developed for curing the difference angles in fracture bone and the lengthening bar for curing the difference length in fracture bone. Both experiments and FE analysis were performed to compare the elastic stiffness in several loading modes and to improve the functional external fixator system for the bone deformity. The FE model using the compressive and bending FE analysis was applied to the FE analysis due to the angle differences. The results show that the compressive stiffness value in experiment was 175.43N/mm; the bending stiffness value in experiment was 259.74N/mm; compressive stiffness value in FEM was 188.67N/mm; bending stiffness value in FEA was 285.71N/mm. The errors between experiments and FEA were less than 10%. The maximum stress (157MPa) to the angle of clamp was lower than the yield stress (176.4MPa) of SUS316L. The stiffnesses in both axial compressive and bending of the new fixator are about 2 times higher than other products except EBI (2003).

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2004.10a
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• pp.1248-1251
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• 2004

The functional external fixator system for bone deformity near joints in legs using the worm gear was developed for curing the difference angles in fracture bone and the lengthening bar for curing the difference length in fracture bone. Both experiments and FE analysis were performed to compare the elastic stiffness in several loading modes and to improve the functional external fixator system for bone deformity near joints in legs. The FE model using the compressive and bending FE analysis was applied the FE analysis due to the angle differences. The results show that the compressive stiffness value in experiment was 175.43N/mm, the bending stiffness value in experiment was 259.74N/mm, compressive stiffness value in FEM was 188.67N/mm, bending stiffness value in FEA was 285.71N/mm. The errors between experiments and FEA were less than 10％. The maximum stress (157MPa) to the angle of clamp was lower than the yield stress (176.4MPa) of SUS316L. The stiffnesses in both axial compressive and bending of the new fixator are about 2 times higher than other products except EBI (2003).

• International journal of advanced smart convergence
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• v.9 no.3
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• pp.199-206
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• 2020

A wheelchair is an essential rehabilitation assistant device for the movement of paraplegia patients and generally paralyzed patients who cannot walk normally. In particular, the applicability of the manual/motorized wheelchair is gradually increasing. Until now, decelerators using belt, chain and worm gears, etc have been widely used. However, a decelerator takes a large space although it is a simple device and thus is not ideal for the driving part of manual/motorized wheelchair. For these reasons, in this study we developed a driving part producing a large driving force through a decelerator using planetary gears rather than conventional worm gear-based decelerator. We designed the tooth profile of the planetary gears for decelerator using Kisssoft program, In addition, we designed the driving part so as to apply it to the wheels of conventional wheelchairs, and then optimized the mechanism for the principles of manual/motorized transposition of the driving part and the operational principles. Based on the results of this study, we finally designed and manufactured a driving part for wheelchair decelerator in the form of planetary gears with 1 sun gear, 2 planetary gears and 1 ring gear.

• Journal of Mechanical Science and Technology
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• v.20 no.2
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• pp.234-241
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• 2006

A functional external fixator system for bone deformity near the joints using worm gear was developed for curing the angle difference in fracture bones while the lengthening bar was developed for curing the differences in length, also in fracture bones. Both experiments and FE analysis were performed to compare the elastic stiffness in several loading modes and to improve the functional external fixator system for bone deformity near joints. The FE model using compressive and bending FE analysis was applied due to the angle differentiations. The results indicate that compressive stiffness value in the experiment was 175.43N/mm, bending stiffness value in the experiment was 259.74 N/mm, compressive stiffness value in the FEA was 188.67 N/mm, and bending stiffness value in the FEA was 285.71 N/mm. Errors between experiments and FEA were less than $10\%$ in both the 'compressive stiffness and the bending stiffness. The maximum stress (157 MPa) applied to the angle of the clamp was lower than the yield stress (176.4 MPa) of SUS316L. The degree of stiffness in both axial compression and bending of the new fixator are about 2 times greater than other products, with the exception of EBI (2003).

• Molecules and Cells
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• v.44 no.3
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• pp.160-167
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• 2021

The determinant factors of an organism's size during animal development have been explored from various angles but remain partially understood. In Caenorhabditis elegans, many genes affecting cuticle structure, cell growth, and proliferation have been identified to regulate the worm's overall morphology, including body size. While various mutations in those genes directly result in changes in the morphological phenotypes, there is still a need for established, clear, and distinct standards to determine the apparent abnormality in a worm's size and shape. In this study, we measured the body length, body width, terminal bulb length, and head size of mutant worms with reported Dumpy (Dpy), Small (Sma) or Long (Lon) phenotypes by plotting and comparing their respective ratios of various parameters. These results show that the Sma phenotypes are proportionally smaller overall with mild stoutness, and Dpy phenotypes are significantly stouter and have disproportionally small head size. This study provides a standard platform for determining morphological phenotypes designating and annotating mutants that exhibit body shape variations, defining the morphological phenotype of previously unexamined mutants.

• Molecules and Cells
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• v.45 no.9
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• pp.649-659
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• 2022

A long-term energy nutritional imbalance fundamentally causes the development of obesity and associated fat accumulation. Lysosomes, as nutrient-sensing and lipophagy centers, critically control cellular lipid catabolism in response to nutrient deprivation. However, whether lysosome activity is directly involved in nutrient-induced fat accumulation remains unclear. In this study, worm fat accumulation was induced by 1 mM glucose or 0.02 mM palmitic acid supplementation. Along with the elevation of fat accumulation, lysosomal number and acidification were also increased, suggesting that lysosome activity might be correlated with nutrient-induced fat deposition in Caenorhabditis elegans. Furthermore, treatments with the lysosomal inhibitors chloroquine and leupeptin significantly reduced basal and nutrient-induced fat accumulation in C. elegans. The knockdown of hlh-30, which is a critical gene in lysosomal biogenesis, also resulted in worm fat loss. Finally, the mutation of aak-2, daf-15, and rsks-1 showed that mTORC1 (mechanistic target of rapamycin complex-1) signaling mediated the effects of lysosomes on basal and nutrient-induced fat accumulation in C. elegans. Overall, this study reveals the previously undescribed role of lysosomes in overnutrition sensing, suggesting a new strategy for controlling body fat accumulation.

• Journal of the Korean Professional Engineers Association
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• v.12 no.3
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• pp.18-22
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• 1979

"In summary, the freezing facilitty manufacturing industry has a bright prospects for further development. So followings are recommended: 1) The import restriction policy should be continued to expand the demand for the 10callT manufactured facilities, 2) Training of local people and import of advanced technologies should be encouraged 3) The capacities of the local manufacturing industry should be expanded to meet the: increasing demand for the facilities, 4) Further incentives should be affered to the freezing & cold storage sector for the repla¬cement of the worm-out facilities 5) The marketing channel of marine products should be reorganized into ""cold-chain system"" by providing a legislative supports."