• Title/Summary/Keyword: world of difference

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Metastatic Pancreatic Carcinoma and Experience with FOLFIRINOX - a Cross Sectional Analysis From a Developing Country

  • Zahir, Muhammad Nauman;Jabbar, Adnan Abdul
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.6001-6006
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    • 2015
  • Background: Pancreatic cancer is the fourth leading cause of cancer related death with median survival ranging from 3 to 6 months for metastatic disease. Palliative chemotherapy has been the backbone of treatment in advanced stage and has evolved over time. Data pertaining to the disease are scarce from our part of the world where treatment poses a significant challenge due to lack of resources. Materials and Methods: A retrospective chart review was performed for all patients presenting with stage IV pancreatic carcinoma at a tertiary care hospital in Karachi, Pakistan between January 2008 and December 2012. Data were collected using a pre-designed, coded questionnaire looking at patient characteristics, treatment given and outcome. Results: 101 patients were found to be eligible. Mean age was $56.7{\pm}12.8years$, the male to female ratio was 2:1 and most patients had a good performance status. More than half of the tumors were located in the head (57%, n=58) and almost all were adenocarcinomas (95%, n=96). Some 58% (n=59) received first line chemotherapy of which 49% (n=29) received gemcitabine-based regimens and 39% (n=23) received FOLFIRINOX. The median progression free survival for gemcitabine based treatment was 2.9 months (IQR=1.6-5.6) as opposed to 7.3 months (IQR=4.5-9.2) for FOLFIRINOX (P=0.02). Median overall survival was 4.9 months (IQR=2.3-9.5) for first line gemcitabine based treatment and 10.5 months (IQR=7.0-13.2) for first line FOLFIRINOX therapy (P=0.002). Patients on FOLFIRINOX had better survival across all subgroups. Inpatient admissions and dose reductions were more frequent with FOLFIRINOX but the difference between the two regimens was not statistically significant. FOLFIRINOX could be successfully administered as outpatient therapy to a number of patients. Conclusions: FOLFIRINOX remains a suitable first line option in patients with metastatic pancreatic cancer with good performance status even in a resource-poor country where diagnostic and supportive care facilities may be less than optimal and cost is a limitation.

An Implementation Method of Virtual Environment Physical Properties (가상물체의 물리적 속성 구현 방법)

  • Im, Chang-Hyuck;Lee, Min-Geun;Lee, Myeong-Won
    • Journal of the Korea Computer Graphics Society
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    • v.13 no.1
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    • pp.25-32
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    • 2007
  • Computer graphics technology has advanced such that all objects can be represented within a computer display. However, because computer displays have a finite resolution, the variety of objects that can be realistically represented together in the same view is restricted by the difference in their relative size. In addition, objects cannot be rendered according to their physical properties in terms of real length units in current computer graphics technology. To solve these problems, we have defined a method that allows objects to be described using real-world physical property units, such as metric units, in a computer graphics system, and developed a 3D browser based on X3D, which implements the concept of relative proportion properties.

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A Study of Sustainable Architectural Design Elements Based on the Classification of Natural Elements (자연요소 중심으로 분류한 친환경 건축계획 요소에 관한 연구)

  • Yim, Su Hyun;Park, Hyeon Soo
    • KIEAE Journal
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    • v.10 no.5
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    • pp.3-12
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    • 2010
  • Sustainable design is getting to be controversial issue in all industries over the world particularly, in architecture as the amount of energy usage in architecture occupies 40%. Therefore, it is essential to make the standard for the sustainable design. In order to construct the sustainable design, firstly it should be considered that sustainable design elements based on natural resources to increase building energy efficiency is established and classified. The method of sustainable design divides into passive design and active design. Passive design method should be examined with active one simultaneously for more efficient usage of energy. Next, the study is followed how the sustainable design elements is adopted in buildings through the comparison of cases study of domestic and oversea. The result of case study shows similar adoption of sustainable design elements between oversea and domestic. However, the difference is shown in the building orientation and shape and the window size and position in Solar energy as well as high performance structure in Heat energy. These elements are the most significant elements in order to reduce energy load. In oversea, sustainable design is generated by architects, a client, and consultants based on the close cooperation in the beginning of early design phase before deciding building shape and envelope while in the domestic field adoption for sustainable design is conducted after deciding building shape and material. In order to design sustainable architecture more study is necessary in early stage for Zero Carbon and reducing building energy load through relation with specialists, a client and architects.

An Enhanced Counterpropagation Algorithm for Effective Pattern Recognition (효과적인 패턴 인식을 위한 개선된 Counterpropagation 알고리즘)

  • Kim, Kwang-Baek
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.12 no.9
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    • pp.1682-1688
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    • 2008
  • The Counterpropagation algorithm(CP) is a combination of Kohonen competition network as a hidden layer and the outstar structure of Grossberg as an output layer. CP has been used in many real applications for pattern matching, classification, data compression and statistical analysis since its learning speed is faster than other network models. However, due to the Kohonen layer's winner-takes-all strategy, it often causes instable learning and/or incorrect pattern classification when patterns are relatively diverse. Also, it is often criticized by the sensitivity of performance on the learning rate. In this paper, we propose an enhanced CP that has multiple Kohonen layers and dynamic controlling facility of learning rate using the frequency of winner neurons and the difference between input vector and the representative of winner neurons for stable learning and momentum learning for controlling weights of output links. A real world application experiment - pattern recognition from passport information - is designed for the performance evaluation of this enhanced CP and it shows that our proposed algorithm improves the conventional CP in learning and recognition performance.

Comparative Analysis of Three Dragon-man Nicknames Used by Kim Junghee (김정희가 사용한 명호 세 용정의 비교 분석)

  • Choi, Joon-Ho
    • Journal of Convergence for Information Technology
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    • v.9 no.10
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    • pp.94-100
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    • 2019
  • This study presents the superiority of his calligraphy by analyzing the use, meaning, and calligraphy of nickname three dragon-man(yong-jeong) written by Kim Junghee before and after exile in Jeju Island. Based on the basic structure of the three dragon-man, the relationship between the times, the context, and the characters was studied. Through this change process, the difference of art engineering with other works was analyzed. Kim Junghee intentionally went through a difficult situation by using a nickname with a dragon. He wrote different meanings, uses, and typefaces of the nickname three dragon-man, depending on the circumstances. Finally, Kim Junghee used 'three dragon-man' to King Heonjong and Monk Choui to express his feelings and intentions. His writing was excellent in art engineering and unique in the world. All were found to be supported by his epigraphy insights. The results of this study will be a new methodology for analyzing the meaning of nicknames of ordinary artists.

Comparative Analysis of Information Security Textbooks for Chinese Elementary and Secondary Students (중국의 초·중등학생 대상 정보보호 교재 비교 고찰)

  • Eunsun Choi;Namje Park
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.3
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    • pp.183-192
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    • 2023
  • Digital transformation is taking place rapidly around the world. As the development of digital technology becomes very fast, more information is expected to be digitized. Therefore, the possibility of cyber threats is increasing in transmitting and storing sensitive information such as personal and financial information online. In this paper, we compared and analyzed information security textbooks for elementary and secondary school students in China, where the recent development of artificial intelligence and digital transformation are rapidly occurring. After we collected related textbooks, textbooks suitable for analysis were selected. Then, we analyzed the external and internal systems of the textbooks separately. As a result of the external system analysis, all the textbook covers were properly produced, but the quality difference was significant among textbooks. In the case of textbooks for elementary school students, the excellence of layout and content placement was noticed. On the other hand, due to the internal system analysis, various contents were not included evenly when looking at the learning contents based on the "information society responsibility" learning goals presented in China. Through this paper, we hope to provide implications for information security-related education and textbook development research.

The Issues and Characteristics of the Preliminary Draft Convention on International Contracts Concluded or Evidenced by Data Message (전자계약에 관한 국제협약 예비초안의 논점과 특징에 관한 고찰)

  • Choi, Seok-Beom;Park, Jong-Suk
    • International Commerce and Information Review
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    • v.5 no.1
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    • pp.85-100
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    • 2003
  • Legal rules applying to the commerce and international commerce in particular contracts, proper law, jurisdiction and so on, have improved with time and experience. Engaging in e-commerce on the World Wide Web may expose the company to the risk of being sued in any foreign country where Internet user can establish a legal claim. The modem law of contracts is highly sophisticated and difficult to understand. With contracts created in cyberspace, the basic rules are no difference that we can find. However, there are situations in e-commerce that are altogether new and to which the existing rules cannot apply. Here uncertainty and business risk is too high for trading partners to deal with certainty. Therefore existing law must change to e-commerce law so that it provides certainty and enforceability over e-commerce. UNCITRAL Working Group on Electronic Commerce prepared the Preliminary Draft Convention on [International] Contracts Concluded or Evidenced by Data Message from the thirty-ninth session in 2002 which applies to international contracts concluded or evidenced by means of data messages. An electronic contract is concluded when the acceptance of an offer becomes effective, and an offer becomes effective when it is received by the offeree, and an acceptance of an offer becomes effective when the indication of assent is received by the offeror according to this Convention. Electronic contract may be concluded by the interaction of an automated computer system and natural person or by the interaction of automated computer systems, and a contract formed by a natural person that accesses an automated computer system of another person has no legal effect in case the neutral person made a material error in a data message.

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Deep Neural Networks Learning based on Multiple Loss Functions for Both Person and Vehicles Re-Identification (사람과 자동차 재인식이 가능한 다중 손실함수 기반 심층 신경망 학습)

  • Kim, Kyeong Tae;Choi, Jae Young
    • Journal of Korea Multimedia Society
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    • v.23 no.8
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    • pp.891-902
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    • 2020
  • The Re-Identification(Re-ID) is one of the most popular researches in the field of computer vision due to a variety of applications. To achieve a high-level re-identification performance, recently other methods have developed the deep learning based networks that are specialized for only person or vehicle. However, most of the current methods are difficult to be used in real-world applications that require re-identification of both person and vehicle at the same time. To overcome this limitation, this paper proposes a deep neural network learning method that combines triplet and softmax loss to improve performance and re-identify people and vehicles simultaneously. It's possible to learn the detailed difference between the identities(IDs) by combining the softmax loss with the triplet loss. In addition, weights are devised to avoid bias in one-side loss when combining. We used Market-1501 and DukeMTMC-reID datasets, which are frequently used to evaluate person re-identification experiments. Moreover, the vehicle re-identification experiment was evaluated by using VeRi-776 and VehicleID datasets. Since the proposed method does not designed for a neural network specialized for a specific object, it can re-identify simultaneously both person and vehicle. To demonstrate this, an experiment was performed by using a person and vehicle re-identification dataset together.

Initiating Events Study of the First Extraction Cycle Process in a Model Reprocessing Plant

  • Wang, Renze;Zhang, Jiangang;Zhuang, Dajie;Feng, Zongyang
    • Journal of Radiation Protection and Research
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    • v.41 no.2
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    • pp.117-121
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    • 2016
  • Background: Definition and grouping of initiating events (IEs) are important basics for probabilistic safety assessment (PSA). An IE in a spent fuel reprocessing plant (SFRP) is an event that probably leads to the release of dangerous material to jeopardize workers, public and environment. The main difference between SFRPs and nuclear power plants (NPPs) is that hazard materials spread diffusely in a SFRP and radioactive material is just one kind of hazard material. Materials and Methods: Since the research on IEs for NPPs is in-depth around the world, there are several general methods to identify IEs: reference of lists in existence, review of experience feedback, qualitative analysis method, and deductive analysis method. While failure mode and effect analysis (FMEA) is an important qualitative analysis method, master logic diagram (MLD) method is the deductive analysis method. IE identification in SFRPs should be consulted with the experience of NPPs, however the differences between SFRPs and NPPs should be considered seriously. Results and Discussion: The plutonium uranium reduction extraction (Purex) process is adopted by the technics in a model reprocessing plant. The first extraction cycle (FEC) is the pivotal process in the Purex process. Whether the FEC can function safely and steadily would directly influence the production process of the whole plant-production quality. Important facilities of the FEC are installed in the equipment cells (ECs). In this work, IEs in the FEC process were identified and categorized by FMEA and MLD two methods, based on the fact that ECs are containments in the plant. Conclusion: The results show that only two ECs in the FEC do not need to be concerned particularly with safety problems, and criticality, fire and red oil explosion are IEs which should be emphatically analyzed. The results are accordant with the references.

A Study of the Next Generation Ubiquitous Flight Information System and a Design (차세대 유비쿼터스 비행정보 시스템의 연구와 설계)

  • Park, Wan-Soon;Yang, Hae-Sool
    • Journal of the Korea Society of Computer and Information
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    • v.13 no.4
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    • pp.221-230
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    • 2008
  • We Studied current Flight Information System everyone employing, and this paper designed a next generation Ubiquitous Flight Information System. Studied a Ubiquitous Flight Information System regarding AVOD, game TV, cellular phone, cabin Internet use for a customer, and airline and control of Air Traffic Service, Air Traffic Control, in seat reservation, transportation, ticketing and luggage back-tracking and airplanes in earthly service. We Designed for a Next Generation Ubiquitous Flight Information System and for necessary for network security, system security of information security system, and derived from comparative analysis of improvement point and difference to existing Ubiquitous Flight Information System and Next Generation Ubiquitous Flight Information as was based on result of research. Present vision to aerial the result of research world of this paper related industry, and ensure safety and communication efficiency and a customer and flight satisfaction, efficiency, and will reclaim the new horizon to the Flight Information Industry.

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