• Title/Summary/Keyword: withdrawal time

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A Pilot Study of Brief Eye Movement Desensitization and Reprocessing(EMDR) for Treatment of Acute Phase Schizophrenia (급성기 정신분열병의 치료로서 단기적인 안구운동 민감소실 및 재처리요법에 대한 예비연구)

  • Kim, Daeho;Choi, Joonho;Kim, Seok Hyeon;Oh, Dong Hoon;Park, Seon-Cheol;Lee, Sun Hye
    • Korean Journal of Biological Psychiatry
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    • v.17 no.2
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    • pp.94-102
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    • 2010
  • Objectives : Eye movement desensitization and reprocessing(EMDR) is a novel, time-limited psychotherapy originally developed for treatment of psychological trauma. The effectiveness of this therapy has been validated only for posttraumatic stress disorder ; however, EMDR is often applied to other psychiatric illnesses, including other anxiety disorders and depression. This pilot study tested the efficacy of EMDR added to the routine treatment for individuals with acute stage schizophrenia. Methods : This study was conducted in the acute psychiatric care unit of a university-affiliated training hospital. Inpatients diagnosed with schizophrenia were randomly assigned to either three sessions of EMDR, three sessions of progressive muscle relaxation(PMR) therapy, or only treatment as usual(TAU). All the participants received concurrent typical treatments(TAU), including psychotropic medication, individual supportive psychotherapy and group activities in the psychiatric ward. The Positive and Negative Syndrome Scale(PANSS), the Hamilton Depression Rating Scale and the Hamilton Anxiety Rating Scale were administered by a clinical psychologist who was blinded to the patients' group assignment. Results : Forty-five patients enrolled and forty patients(89%) completed the post-treatment evaluation. There were no between-group differences in the withdrawal rates of patients during the treatment or at the three-month follow-up session. All three groups improved significantly across each of the symptomatic domains including schizophrenia, anxiety, and depressive symptoms. However, a repeated measures ANOVA revealed no significant differences among the groups over time. Effect size for change in total PANSS scores was also similar across treatment conditions, but effect size for negative symptoms was large for EMDR(0.60 for EMDR, 0.39 for PMR and 0.21 for TAU only). Conclusion : These findings supported the use of EMDR in treating the acute stage of schizophrenia but the results failed to confirm the effectiveness of the treatment over the two control conditions in three sessions. Further studies with longer courses of treatment, more focused target dimensions of treatment, and a sample of outpatients are necessary.

A Study on the Use Smartphone of Radiological Technologist (방사선사의 스마트폰 이용에 관한 연구)

  • Jeong, Bong-Jae
    • Journal of the Korean Society of Radiology
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    • v.14 no.7
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    • pp.915-922
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    • 2020
  • This study analyzed the content of use Tendency and addiction according to smartphone use of targeting radiological Technologist working in Gyeongnam area. The tool used as the data for the study is a survey. From April 21 to May 31, 2019, a total of 330 questionnaires were distributed to radiological Technologist working at medical institutions in Gyeongnam, and 300 copies suitable for the study were SPSS/PC Ver 18.0 program for Analysis was performed using. The factors of the study subject's tendency to use smartphone were communication, information, leisure, and convenience. As for the addiction factors, a total of 37 questions were analyzed, including daily living disorder, virtual world orientation, tolerance, and withdrawal. Smartphone-related characteristics were set as monthly average fee, usage time, and SNS usage time, and technical statistics, t-test, ANOVA, correlation and regression analysis were performed. The radiological Technologist tendency to use smartphones was 3.10±.55 points, which was average, and smartphone addiction was 2.34±.62 points, which was lower than the average. It was found that there was a significant correlation between the radiological Technologist Tendency to use smartphone and addiction. The effect of radiological Technologist tendency to use smartphone on addiction it was found to account for 10.8%. Through this study, it can be said that it is important to analyze the addiction factors according to the tendency use smartphone of radiological Technologist and to prepare a desirable plan for smartphone use.

A Study of Longitudinal Changes in Mother-Child Interaction and its Effect on Media Device Addiction (모-자녀 상호작용 변화 양상에 따른 자녀의 미디어 기기 중독 차이)

  • Yeon, Eun Mo;Choi, Hyo-Sik
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.12
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    • pp.346-353
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    • 2020
  • The purpose of this study was to explore types of longitudinal changes in interactions between mothers and 4-year-old children in primary school as well as the effects on media device addiction. To explore interaction types between mothers and children, latent class growth modeling (LCGM) and BCH were used in a three-step approach. Data from the 6-10th wave of the Panel Study of Korea Children were used. First, the trajectory of the mother-child interactions was linear and decreased across time. This linear decrease was classified into the following three trajectories: high-decreasing, average-deceasing, and low-decreasing. Second, BCH was performed to examine media device addiction in each trajectory, and the findings show that children who had low initial mother-child interactions over time were more likely to experience daily disturbances in adaptive functions such as withdraw or tolerance than other groups of children. The results indicate that maximizing the quality of mother-child interactions in childhood through primary school can lower media device addiction in children.

Dynamic of heat production partitioning in rooster by indirect calorimetry

  • Rony Lizana, Riveros;Rosiane, de Sousa Camargos;Marcos, Macari;Matheus, de Paula Reis;Bruno Balbino, Leme;Nilva Kazue, Sakomura
    • Animal Bioscience
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    • v.36 no.1
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    • pp.75-83
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    • 2023
  • Objective: The objective of this study was to describe a methodological procedure to quantify the heat production (HP) partitioning in basal metabolism or fasting heat production (FHP), heat production due to physical activity (HPA), and the thermic effect of feeding (TEF) in roosters. Methods: Eighteen 54-wk-old Hy Line Brown roosters (2.916±0.15 kg) were allocated in an open-circuit chamber of respirometry for O2 consumption (VO2), CO2 production (VCO2), and physical activity (PA) measurements, under environmental comfort conditions, following the protocol: adaptation (3 d), ad libitum feeding (1 d), and fasting conditions (1 d). The Brouwer equation was used to calculate the HP from VO2 and VCO2. The plateau-FHP (parameter L) was estimated through the broken line model: HP = U×(R-t)×I+L; I = 1 if t<R or I = 0 if t>R; Where the broken-point (R) was assigned as the time (t) that defined the difference between a short and long fasting period, I is conditional, and U is the decreasing rate after the feed was withdrawn. The HP components description was characterized by three events: ad libitum feeding and short and long fasting periods. Linear regression was adjusted between physical activity (PA) and HP to determine the HPA and to estimate the standardized FHP (st-FHP) as the intercept of PA = 0. Results: The time when plateau-FHP was reached at 11.7 h after withdrawal feed, with a mean value of 386 kJ/kg0.75/d, differing in 32 kJ from st-FHP (354 kJ/kg0.75/d). The slope of HP per unit of PA was 4.52 kJ/mV. The total HP in roosters partitioned into the st-FHP, termal effect of feeding (TEF), and HPA was 56.6%, 25.7%, and 17.7%, respectively. Conclusion: The FHP represents the largest fraction of energy expenditure in roosters, followed by the TEF. Furthermore, the PA increased the variation of HP measurements.

How has Brexit changed the UK: Deepening of Social Division and Increase of Rancour (브렉시트(Brexit)가 바꾼 영국: 사회적 분열의 심화와 증오의 확산)

  • Sungwook Yoon
    • Analyses & Alternatives
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    • v.7 no.2
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    • pp.79-110
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    • 2023
  • The purpose of this research is to explore the relation between Brexit and division in various areas within the British society. This research can lead to understanding how division of the British society and the decision of Brexit was mutually influenced. The UK's withdrawal from the EU has been explained mainly through the relations between the EU and the UK; therefore, issues of immigration, EU regulation, and the UK's EU rebate are considered as major reasons. In addition, 'British identity' or 'British exceptionalism' existing in the British society and politics for a long time has been regarded as a reason for Brexit. Although it is generally accepted that Brexit results in the division in the British society, the reasons mentioned above have limitation to explain the result of referendum and the division of the British society in the post-Brexit era. In this sense, this research explores the division in various areas - generation, social grade including income and education level, value and region, etc. - revealed in the British society is not the result of Brexit; rather, this research argues division deeply rooted in the British society before referendum is the root cause of Brexit. The division in various areas immanent in the British society for a long time is complicatedly intertwined, and the decision on Brexit by referendum has led to solidifying the division of the British society. Having considered this division in the British society has been expanded to rancour, it is necessary for the UK to establish appropriate policies for national cohesion.

Legislation on Aid in Dying in France (조력사망에 관한 프랑스의 입법 동향)

  • Jieun Lee
    • The Korean Society of Law and Medicine
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    • v.25 no.1
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    • pp.193-222
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    • 2024
  • From a global trend, discussions on the patient's death with dignity are gradually progressing from the issue of withdrawal of life-sustaining treatment to the issue of whether to allow assisted death and its requirements. Several states in the United States and Western European countries such as Canada, Belgium, and the Netherlands have institutionalized treatment to accelerate the time of death through the assistance of doctors. In France, after a long period of raising and reviewing issues, discussions on related legislation are taking place at a slower pace than in other European countries. In France, social discussions and legislative attempts on death with dignity have been actively conducted since the late 20th century. The Leonetti Act of 2005 prohibited the continuation of meaningless treatment against the will of patients, and after the Clay-Leonetti Act of 2016, it was legalized to administer intensive and continuous sedatives to patients until death. However, unlike many neighboring European countries, treatment that speeds up the time of death itself is still prohibited in France, even if the patient wants. As the existential and universal question of whether to allow dying patients to die painlessly with the help of a doctor has recently emerged as an important issue, a number of lawmakers have submitted legislation to legalize assisted death. This paper examines the legislative process developed in relation to patients' rights to dignified death in France, and compares and reviews French legislation that attempts to legalize assisted death with the amendment to the Korean Life-Sustaining Treatment Act.

Study on the changes of sulfamethnzine residues in serum and practical organs of rats orally administrated with sulfamethnzine sodium (Rat에 sulfamethazine sodium 경구투여 후 혈청 및 실질장기내 sulfamethazine의 잔류량 추이에 관한 연구)

  • 도재철;이영미;조민희;신상희;박희주;송희종;정종식
    • Korean Journal of Veterinary Service
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    • v.23 no.4
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    • pp.321-333
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    • 2000
  • In order to know the depletive changes of sulfamethazine residues in senlm and practical organs of rats orally administered with sulfamethazine sodium(SMS), the concentration of sulfamethazine was measured in serum and tissue(kidney, liver, spleen, testis, and skeletal muscle) of rats with using high performance liquid chromatography(HPLC). SMS was orally administrated to sprague-dawley male rats(body weight, 200~300g) with using sonde at the rate of 20mg/100g body weight(recommended therapeutic dose) on once a day for 3 days. There were investigated the depletive changes of the sulfamethazine in serum, kidney, liver, spleen, testis and skeletal muscle of rat at the time 8 hours, 1st, 2nd, 3rd, 4th, 5th and 6th day after administration SMS, respectively. The results obtained were summarized as follows; 1. After oral administration of the SMS, the mean concentrations of sulfamethazine in serum according to the time lapsed were showed 215.53$\pm$42.99ppm at the 8 hours after withdrawal of medicated sulfamethazine. And gradually according to the time lapsed, the concentrations of sulfamethazine residues in serum were significantly (p<.05) decreased 25.87$\pm$5.18ppm at 1st day, 2.30$\pm$0.61ppm at 3rd day and 0.11$\pm$0.02ppm at 6th day respectively. 2. The mean concentrations of sulfamethazine in kidney, liver, spleen, muscle and testis according to the time lapsed after administration SMS were showed 83.82$\pm$12.16, 81.77$\pm$12.88, 36.96$\pm$5.35, 35.96$\pm$TEX>$\pm$1.39 and 27.89$\pm$1.92 ppm at the 8 hours, respectively. And gradually according to the time lapsed, the concentrations of sulfamethazine residues in the each of samples were significantly(p<.05) decreased such as 7.15$\pm$0.26, 5.62$\pm$0.72, 2.43$\pm$0.29, 1.99$\pm$0.14 and 3.11$\pm$0.48 ppm at 1st day, 0.52$\pm$0.04, 1.32$\pm$0.22, 0.13$\pm$0.03, 0.15$\pm$0.06 and 0.26$\pm$0.11ppm at 3rd day, and 0.03$\pm$0.01, 0.11$\pm$0.03, 0.02$\pm$0.01, 0.009$\pm$0.001 and 0.02$\pm$0.01 ppm at 6th day, respectively. 3. After oral administration of the SMS to rats, the residual concentrations of sulfamethazine in skeletal muscle were significantly (p<.05) decreased 35.96$\pm$1.39 to 0.009$\pm$$\pm$0.001 ppm between 8 hours and 6th day, respectively From the 4th day, the residual concentrations of sulfamethazine were showed 0.10$\pm$0.04 ppm below 0.1 ppm at the permitted limit concentration of muscle in Korea. In conclusion, this study could be suggested the relationship between administrated period, doses of sulfonamides and residual aspects of serum and practical organs, and the importance of observing ceasing period of antibiotic drugs before forwarding livestocks to slaughter.

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Stochastic Programming Model for River Water Quality Management (추계학적 계획모형을 이용한 하천수질관리)

  • Cho, Jae Heon
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.14 no.1
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    • pp.231-243
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    • 1994
  • A stochastic programming model for river water quality management was developed. River water quality, river flow, quality and flowrate of the wastewater treatment plant inflow were treated as random variables in the model. Withdrawal for water supply and submerged weir reaeration were included in the model itself. A probabilistic model was formulated to compute the expectation and variance of water quality using Streeter-Phelps equation. Chance constraints of the optimization problem were converted to deterministic equivalents by chance constrained method. Objective function was total annual treatment cost of all wastewater treatment plants in the region. Construction cost function and O & M cost function were derived in the form of nonlinear equations that are functions of treatment efficiency and capacity of treatment plant. The optimization problem was solved by nonlinear programming. This model was applied to the lower Han River. The results show that the reliability to meet the DO standards of the year 1996 is about 50% when the treatment level of four wastewater treatment plants in Seoul is secondary treatment, and BOD load from the tributary inflows is the same as present time. And when BOD load from Tanchon, Jungrangchon, and Anyangchon is decreased to 50%, the reliability to meet the DO standards of the year 1996 is above 60%. This results indicated that for the sake of the water quality conservation of the lower Han River, water quality of the tributaries must be improved, and at least secondary level of treatment is required in the wastewater treatment plants.

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The Variation of Serum Thyroglobulin Measured after Thyrogen Administration (Thyrogen 투여 후 측정된 Thyroglobulin 농도변화)

  • Kim, Ji-Na;An, Jae-seok;Won, Woo-Jae
    • The Korean Journal of Nuclear Medicine Technology
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    • v.22 no.1
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    • pp.80-83
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    • 2018
  • Purpose Assessment of Serum Thyroglobulin (sTg) value in total thyroidectomy patients having an ablation dose of radioactive iodine indicates remaining cancer or metastasis. Especially, sTg in patients on withdrawal thyroxine or thyrogen administration for radioiodine ablation is an important indicator to determine the direction of further treatment and prognosis. Current guidelines suggest measurement of sTg is performed at 72 hours after the last injection of thyrogen. and assumes that sTg reaches maximum serum levels at that time. The purpose of this study is to evaluate the variation of sTg measured after thyrogen administration. Materials and Methods We compared with sTg performed at 24hours(D0) and 72hours(D2) after the last injection of thyrogen. We reviewed D0 and D2 from 276 patients were divided them into three groups according to ablation dose of radioactive iodine, 5mCi(A group), 30~80mCi(B group) and 100~200mCi(C group). We used T-test for comparison between D0 and D2. sTg was measured in serum using immunoradiometric assay (Tg-plus RIA; BRAHMS, Berlin, Germany). Results There is no critical variation between D0 and D2 in A group(n=100)(P=0.32), The case of increase(D2>D0) is 45, no change(D2=D0) is 23, decrease(D2D0 is 91, D2=D0 is 28, D2D0 is 19, D2=D0 is 2. The biggest increase is 143.6 ng/mL from 98.4 to 242. Conclusion There was a significant difference in the group over 30mCi. and the case of D2>D0 is 45%, 58.7%, 90.5% for each group. therefore, D2 increased as the dose of radioactive iodine increased. Furthermore, the most sTg values of D0 and D2 are variation under 2.0 ng/mL, so reproducibility as well as sensitivity of sTg will be important at values below 2ng/mL.

Nuclear-First Politics of Kim Jung Un Regime and South Korea's Deterrence Strategy (김정은 정권의 선핵(先核) 정치와 한국의 억제전략)

  • Kim, Tae Woo
    • Strategy21
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    • s.39
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    • pp.5-46
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    • 2016
  • North Korea's 4th nuclear test on Jan. 6 and following developments once again awakened the world into seriousness of the nuclear matters on the Korean peninsula. On March 2, UNSC adopted Resolution 2270 which is complemented by Seoul government's measures such as withdrawal from the Gaesung Industrial Complex (Feb. 9) and announcement of unilateral sanction (March 8). Seoul government also strongly urged the international community to strangle North Korea's 'financial resources.' The U.S., Japan, China, and other countries have issued unilateral sanctions to complement the UNSC measure. South Korea and the U.S. conducted their annual joint military drill (Resolve-Foal Eagle) in the largest-ever scale. North Korea, however, responded with demonstration of its nuclear capabilities and announcement of de facto 'nuclear-first' politics. North Korea test-fired a variety of delivery vehicles, threatened nuclear strikes against South Korea and the U.S., and declared itself as an 'invincible nuclear power armed with hydrogen bombs' at the 7th Workers 'Party Congress held in May, 2016. Considering the circumstantial evidences, the North's 4th nuclear test may have been a successful boosted fission bomb test. North Korea, and, if allowed to go on with its nuclear programs, will become a nuclear power armed with more than 50 nuclear weapons including hydrogen bombs. The North is already conducting nuclear blackmail strategy towards South Korea, and must be developing 'nuclear use' strategies. Accordingly, the most pressing challenge for the international community is to bring the North to 'real dialogue for denuclearization through powerful and consistent sanctions. Of course, China's cooperation is the key to success. In this situation, South Korea has urgent challenges on diplomacy and security fronts. A diplomatic challenge is how to lead China, which had shown dual attitudes between 'pressure and connivance' towards the North's nuclear matters pursuant to its military relations with the U.S, to participate in the sanctions consistently. A military one is how to offset the 'nuclear shadow effects' engendered by the North's nuclear blackmail and prevent its purposeful and non-purposeful use of nuclear weapons. Though South Korea's Ministry of Defense is currently spending a large portion of defense finance on preemption (kill-chain) and missile defense, they pose 'high cost and low efficiency' problems. For a 'low cost and high efficiency' of deterrence, South Korea needs to switch to a 'retaliation-centered' deterrence strategy. Though South Korea's response to the North's nuclear threat can theoretically be boiled down into dialogue, sanction and deterrence, now is the time to concentrate on strong sanction and determined deterrence since they are an inevitable mandatory course to destroy the North' nuclear-first delusion and bring it to a 'real denuclearization dialogue.'