• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5473-5476
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• 2013

Background: In our study, the LDH, albumin, hemoglobin, neutrophile, thrombocyte, lymphocyte counts and prognostic significance of neutrophile-lymphocyte and thrombocyte-lymphocyte ratios in NSCLC derived from these counts obtained during regular examinations of patients were examined. Materials and Methods: Histopathologically diagnosed non-small-cell-lung cancer patients between 2008 and 2010 were included in the study. Before the treatment, full blood count including routine lymphocyte count, blood biochemistry examinations including liver (AST, ALT, total protein, Albumin), LDH and kidney (BUN, Cre) function tests were performed. Results: A total of 156 patients, 76 of whom (48.7%) were female and 80 of whom (51.3%) were male were included. Mean hemoglobin level was determined as 12. Overall survival was found to be significantly dependent on whether patients were anemic or not (p: 0.005). Mean LDH level was determined as 233.4. There was nosurvival difference between patients with and without high LDH (p: 0.532). In patients where NLR showed systemic inflammatory response, overall survival was 10.8 months whereas this duration was 19.6 months in patients where the systemic inflammatory response was negative (p: 0.012). In patients where TLR showed systemic inflammatory response, overall survival was 13.6 months whereas this duration was 21.9 months in patients where the systemic inflammatory response was negative (p: 0.04). Conclusions: Molecular methods have been changing rapidly in today's world and they manage the treatment besides defining the prognosis of patients. However, easily accessible and cheap laboratory parameters should be considered in the prognosis of patients besides these new methods.

• 대한정형외과 초음파학회지
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• 제4권2호
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• pp.66-71
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• 2011

목적: 보존적인 치료를 시행 받은 쇄골 골절 환자 중 단순 방사선학적 검사에서 가골 형성이 관찰 되지 않아 지연유합이나 불유합이 의심되는 경우 초음파 검사가 가골 형성여부를 확인하는 검사로서 유용한 가를 알아보고자 하였다. 대상 및 방법: 쇄골 골절로 진단되어 보존적인 치료를 시행 받았으나, 불유합 또는 지연 유합이 의심되는 여섯 명의 남자와 한 명의 여자 환자(평균 38.3세; 범위: 7~70세)를 대상으로 초음파를 시행하였다. 초음파 검사상 가골 형성이 관찰된 경우는 보존적 치료를 지속하였고, 가골 형성이 관찰 되지 않은 경우는 수술적 치료를 시행하였다. 결과: 초음파 검사상 가골 형성을 관찰 할 수 있었던 6예는 보존적인 치료를 지속하여 최종 추시 단순 방사선 검사상 골유합을 확인 할 수 있었다. 초음파 검사상 가골 형성이 관찰되지 않았던 1예는 수술적 치료를 시행하였으며, 수술소견상 골유합 소견을 관찰할 수 없었다. 결론: 초음파 검사는 보존적 치료를 받는 쇄골 골절 환자에서 임상적 및 방사선학적으로 불유합 또는 지연 유합이 의심되는 경우 가골 형성을 평가하는데 있어 유용한 검사 방법으로 불필요한 수술을 피하는 데 기여할 수 있을 것으로 생각한다.

• Pediatric Infection and Vaccine
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• 제3권2호
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• pp.163-167
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• 1996

Aseptic meningitis, the most common infection of the central nervous system, is an acute illness mostly caused by enteroviruses. Cerebrospinal fluid(CSF) has been used for the detection of enteroviral RNA but the detection has been mostly performed in a single CSF specimen obtained during the illness. A major objective was to evaluate the relation of sampling time to the recovery of enteroviral RNA in CSF. Thirty seven CSF specimens were obtained from 24 patients between May and August 1993, when an outbreak of asceptic meningitis by echovirus type 9 occurred. Enteroviral RNA in CSF was detected by polymerase chain reaction(PCR). Data about onset of symptom development were obtained by review of medical records. Enteroviral RNA was detected by PCR in 29 of 37 CSF specimens. PCR yielded positive results in 4 of 5 CSF specimens obtained on day 1 to 3, 10 of 11 on day 4 to 6, 8 of 10 on day 7 to 9, 6 of 8 on day 10 to 12, 1 of 3 on day 13 to 15 postonset. Of 11 patients from each of whom more than one CSF were obtained on different day postonset, PCR yielded positive resutls in 2 of 3 cases in whom enteroviral RNA detection was negative in the first CSF. These results indicate that two or more CSF specimens obtained within 12 days postonset are required for improving the accuracy of the diagnosis of enteroviral meningitis.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제45권3호
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• pp.135-140
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• 2019

Objectives: This study sought to investigate the association between the systemic intake of proton pump inhibitors (PPI) and the early failure of dental implants. Materials and Methods: A retrospective cohort study involving 1,918 dental implants in 592 patients (69 implants in 24 PPI users and 1,849 implants in 568 nonusers, respectively) was conducted. The effect of PPI intake on the osseointegration of dental implants was evaluated using patientand implant-level models. Results: Among 24 PPI users, two patients experienced implant failure, one of whom had three and the other of whom had one failed implant, respectively. Thus, the rate of failure for this population was 8.3%. Separately, 11 nonusers each experienced one implant failure, and the failure rate for these patients was 1.9%. Fisher's exact test revealed statistically significant differences between PPI users and nonusers at the implant level (P=0.002) but failed to show any significance at the patient level (P=0.094). The odds of implant failure were 4.60 times greater among PPI users versus nonusers. Dental implants that were placed in patients using PPIs were found to be 4.30 times more likely to fail prior to loading. Conclusion: The findings of this study suggest that PPI intake may be associated with an increased risk of early dental implant failure.

• 대한통합의학회지
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• 제11권2호
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• pp.61-68
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• 2023

Purpose : In this study, a group art therapy program was applied to mothers who are the main rears of disabled children to confirm its effect by comparing the self-esteem and parenting efficacy of the mothers prior to and after the program. Methods : 17 subjects recruited by using the 2-group prior-after control group study design method were randomly allocated. The study was conducted on 8 subjects in the experimental group for whom an art therapy program is applied and 9 subjects in the control group. The experimental group was subjected to group art therapy lasting 60 minutes once a week. Activity goals and contents were predetermined for each subject for each session, and a total of 10 sessions of the program was applied for 10 weeks. Self-esteem and parenting efficacy prior to and after the program of the subjects were measured by using corresponding self-esteem and parenting efficacy scales. Measurement data were analyzed by using the Mann-Whitney Test. Results : It was possible to observe that the self-esteem and parenting efficacy of the subjects in the experimental group to whom the art therapy program was applied underwent more significant changes in comparison to those of the control group (p<.01). Conclusion : Group art therapy induces social support experiences of group therapy and an improvement of an assertive attitude towards art therapy. Since there was a significant improvement of self-esteem and parenting efficacy in the results of this study when the group art therapy program is applied, it is believed its clinically meaningful application would be possible. In particular, it can be utilized in programs for disabled children in a family unit from the perspective that it improves parenting efficacy, which can impart an affirmative effect not only to the main rear but also to all the family members.

• 수면정신생리
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• 제7권2호
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• pp.79-83
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• 2000

Sleep disturbances are frequently associated with neurological disorders. Sleep disorders interfere with rehabilitation of patients with neurological disorders such as stroke and may increase the severity of their symptoms and recurrence rate of stroke. The treatment of sleep apnea syndrome is particularly important in managing patients with cerebral infarction of whom 50-80% have moderate to severe sleep apnea. Sleep apnea produces not only poor quality sleep but also excessive daytime sleepiness, fatigue and lack of energy. Sleep problems frequently found in patients with dementia are sleep-wake cycle abnormality, fragmentation of sleep, nocturnal insomnia, decreased slow wave sleep and REM sleep, and sleep disordered breathing. The management of sleep disturbances is very important for controlling symptoms such as nocturnal wandering and sundowning syndrome in patients with dementia. Parkinson's disease and epilepsy are other neurological disorders that may have sleep disturbances.

• Journal of Dental Anesthesia and Pain Medicine
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• 제17권2호
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• pp.91-103
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• 2017

General anesthesia is commonly used to facilitate dental treatment in patients with anxiety or challenging behavior, many of whom are children or patients with special needs. When performing procedures under general anesthesia, dental surgeons must perform a thorough pre-operative assessment, as well as ensure that the patients are aware of the potential risks and that informed consent has been obtained. Such precautions ensure optimal patient management and reduce the frequency of morbidities associated with this form of sedation. Most guidelines address the management of pediatric patients under general anesthesia. However, little has been published regarding this method in patients with special needs. This article constitutes a review of the current literature regarding management of patients with special needs under general anesthesia.

• Journal of Korean Neurosurgical Society
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• 제60권3호
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• pp.375-379
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• 2017

Midbrain gliomas are relatively rare neoplasms with a generally benign prognosis, with dissemination or metastasis not previously reported. We describe here a woman, in whom magnetic resonance imaging scans showed hydrocephalus and a tegmental lesion in the upper aqueduct. Endoscopic third ventriculostomy and biopsy were performed; during surgery, a second small lesion was observed in the infundibular recess. Histologically, the two lesions had the characteristics of low grade astrocytoma, suggesting that the midbrain astrocytoma may have been disseminated via the cerebral spinal fluid to the infundibular recess. Postoperatively this patient received radiotherapy for nearly one month. Although patients with these tumors are not usually administered adjunctive therapy, radiation and, combined modality therapy, including surgery, radiotherapy, and chemotherapy, may be beneficial in patients with midbrain gliomas with dissemination.

• Journal of Korean Neurosurgical Society
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• 제30권1호
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• pp.110-113
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• 2001

The cerebral arteriovenous malformation(AVM) rarely coexists with primary intracranial tumor. The authors experienced a patient with intracerebral hematoma due to AVM rupture in whom intracranial meningioma and intracranial aneurysms coexisted. The meningioma was located at convexity of right frontal lobe, and arteriovenous malformation at temporo-occipital lobe of same hemisphere with feeding from right middle cerebral artery, and three intracranial aneurysms exist at the cavernous portion of right internal carotid artery, AVM feeding artery, and intranidal of the AVM. The authors report a rare case of coexisted intracranial AVM, meningioma and aneurysms with review of literatures.

• Journal of Chest Surgery
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• 제46권1호
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• pp.56-59
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• 2013

Cardiac surgery in neonates with congenital heart disease has progressed dramatically in the past three decades. However, low-birth-weight neonates with congenital heart disease continue to challenge the intellectual and technical skills of healthcare professionals. We present a case of a low-birth-weight neonate with pulmonary atresia and a ventricular septal defect, in whom palliation was achieved with a right ventricular outflow tract stent using a hybrid procedure.