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Persistent Post-radiotherapy Pain and Locoregional Recurrence in Head and Neck Cancer- Is There a Hidden Link?

  • Srivastava, Preety;Kingsley, Pamela Alice;Srivastava, Himanshu;Sachdeva, Jaineet;Kaur, Paramdeep
    • The Korean Journal of Pain
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    • v.28 no.2
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    • pp.116-121
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    • 2015
  • Background: To explore the relationship between persistent post-radiotherapy pain and locoregional recurrence in head and neck cancer patients. Methods: Five year retrospective data was reviewed of 86 patients of head and neck cancer treated with radiotherapy who continued to have pain at 6 weeks after completion of treatment. At follow-up after 3 months, these patients were stratified into: Group A (n = 39) constituted of patients whose pain subsided and Group B (n = 47) were patients who continued to have persistent pain. Results: At median follow-up time of 25 months (range: 8-47), one patient (2.6%) and 18 (38.3%) patients in group A and group B had locoregional recurrence respectively (P < 0.0001). Furthermore, group B patients had higher mean pain score levels as compared to group A (P = 0.03). Patients in whom pain subsided within 3 months had statistically much greater disease-free survival in comparison to those with persistent pain (P < 0.0001). Conclusions: Pain in head and neck cancer is an important symptom and should be considered a poor prognostic factor. In the current study, the majority of the patients with persistent pain had recurrent disease as compared to those in whom pain subsided within 3 months of post-treatment. It is suggested that patients with persistent pain need more intense follow-up and should be investigated thoroughly to detect recurrence at an early stage to provide a better quality of life.

Clinical Outcomes of Arteriovenous Graft in End-Stage Renal Disease Patients with an Unsuitable Cephalic Vein for Hemodialysis Access

  • Son, Joung Woo;Ryu, Jae-Wook;Seo, Pil Won;Ryu, Kyoung Min;Chang, Sung Wook
    • Journal of Chest Surgery
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    • v.53 no.2
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    • pp.73-78
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    • 2020
  • Background: As the population of patients with end-stage renal disease has grown older, the proportion of patients with poorly preserved vasculature has concomitantly increased. Thus, arteriovenous grafts (AVG) have been used more frequently to access blood vessels for hemodialysis. Despite this increasing demand, studies of AVG are limited. In this study, we examined the surgical outcomes of upper-limb AVG creation. Methods: Among the arteriovenous fistula formation procedures performed between January 2014 and March 2019 at Dankook University Hospital, 42 cases involved AVG creation. We compared patients in whom the axillary vein was used (group A; brachioaxillary AVG [B-Ax AVG]; n=20) with those in whom upper limb veins were used (group B; brachiobasilic AVG or brachioantecubital AVG; n=22). Results: The 1-year primary patency rate was higher in group A than in group B (57.9% vs. 41.7%; p=0.262). The incidence of postoperative complications was not significantly different between groups. Conclusion: AVG using the axillary vein showed no major differences in safety or functionality compared to AVG using other veins. Therefore, accounting for age, underlying disease, and expected patient lifespan, B-Ax AVG can be considered an acceptable surgical method.

The Effectiveness of 3D FIESTA (Three Dimensional Fast Imaging Employing Steady-state Acquisition) MRI in Sudden Hearing Loss Patients (돌발성 난청 환자에서 3D FIESTA (three dimensional fast imaging employing steady-state acquisition) MRI의 유용성)

  • Cho, Jae-Hwan;Kim, Hyun-Ju;Park, Cheol-Soo
    • Journal of Digital Contents Society
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    • v.11 no.4
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    • pp.425-431
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    • 2010
  • This study explored the effects and the effectiveness of the new method of 3D FIESTA by making quantitative comparison with the conventional 3D FSE method which is frequently employed on patients with sudden hearing loss in clinical settings. For this study, 3D FSE images acquired with 3.0T MR scanner and T2-weighted axial plane 3D FIESTA images were respectively taken from 40 patients diagnosed with Sensorineural Hearing Loss (SSHL). When obtaining those images, sagittal reconstructions oriented perpendicular to the nerve were performed in order to get sagittal images of both right and left internal auditory canal. The findings showed that both SNR and CNR were higher among the group to whom the 3D FIESTA method was applied than the group to whom the conventional 3D FSE method was applied.

Feasibility of Gamma Knife Radiosurgery for Brain Arteriovenous Malformations According to Nidus Type

  • Ja Ho Koo;Eui Hyun Hwang;Ji Hye Song;Yong Cheol Lim
    • Journal of Korean Neurosurgical Society
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    • v.67 no.4
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    • pp.431-441
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    • 2024
  • Objective : Gamma Knife radiosurgery (GKRS) is an effective and noninvasive treatment for high-risk arteriovenous malformations (AVMs). Since differences in GKRS outcomes by nidus type are unknown, this study evaluated GKRS feasibility and safety in patients with brain AVMs. Methods : This single-center retrospective study included patients with AVM who underwent GKRS between 2008 and 2021. Patients were divided into compact- and diffuse-type groups according to nidus characteristics. We excluded patients who performed GKRS and did not follow-up evaluation with magnetic resonance imaging or digital subtraction angiography within 36 months from the study. We used univariate and multivariate analyses to characterize associations of nidus type with obliteration rate and GKRS-related complications. Results : We enrolled 154 patients (mean age, 32.14±17.17 years; mean post-GKRS follow-up, 52.10±33.67 months) of whom 131 (85.1%) had compact- and 23 (14.9%) diffuse-type nidus AVMs. Of all AVMs, 89 (57.8%) were unruptured, and 65 (42.2%) had ruptured. The mean Spetzler-Martin AVM grades were 2.03±0.95 and 3.39±1.23 for the compact- and diffuse-type groups, respectively (p<0.001). During the follow-up period, AVM-related hemorrhages occurred in four individuals (2.6%), three of whom had compact nidi. Substantial radiation-induced changes and cyst formation were observed in 21 (13.6%) and one patient (0.6%), respectively. The AVM complete obliteration rate was 46.1% across both groups. Post-GKRS complication and complete obliteration rates were not significantly different between nidus types. For diffuse-type nidus AVMs, larger AVM size and volume (p<0.001), lower radiation dose (p<0.001), eloquent area location (p=0.015), and higher Spetzler-Martin grade (p<0.001) were observed. Conclusion : GKRS is a safe and feasible treatment for brain AVMs characterized by both diffuse- and compact-type nidi.

Multimedia : Technology Push vs. Customer Pull

  • 정종덕;윤종훈
    • Proceedings of the Korea Association of Information Systems Conference
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    • 1996.11a
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    • pp.110-123
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    • 1996
  • Misunderstanding of multimedia in the computer industry, the confusion of consumers, and the lack of understanding of technology in the human context provide an impetus for examining and speculating on the future of multimedia. "What can a multimedia technology do ?" is not a sufficient question for consumers until we add "for whom." Both how the relevant technology is likely to develop and how human choices would be made are examined with a focus on historical trend in media technology adoption.

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AGING TEST AND SOFTWARE RELIABILITY ANALYSIS METHOD FOR PC-BASED CONTROLLER

  • Song Jun-Yeob;Jang Ju-Su
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.06a
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    • pp.969-973
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    • 2005
  • This paper presents a survey of software reliability modeling and it's application to pre-built software system combined with hardware such as numerical controller based on personal computer systems. Many a systems in these days are much more becoming software intensive and many software intensive systems are safety critical. For this reason, the technique well developed to measure of software reliability is very important for whom to assess such a system. This paper provides a brief idea of method to evaluate such a system's reliability based on hardware performance.

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Costly Lessons From the 2015 Middle East Respiratory Syndrome Coronavirus Outbreak in Korea

  • Lee, Sang-il
    • Journal of Preventive Medicine and Public Health
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    • v.48 no.6
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    • pp.274-276
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    • 2015
  • Since the Middle East respiratory syndrome (MERS) outbreak in the Republic of Korea (hereafter Korea) began on May 11, 2015, a total of 186 persons have been infected by the MERS coronavirus, 38 of whom have died. With this number, Korea becomes second only to the Kingdom of Saudi Arabia in the ranking of cumulative MERS cases. In this paper Korea's unique experience of an outbreak of MERS will be summarized and discussed briefly.

Multimedia : Technology Push vs. Customer Pull

  • 정종덕;윤종훈
    • Proceedings of the Korea Society for Industrial Systems Conference
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    • 1996.10a
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    • pp.110-123
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    • 1996
  • Misunderstanding of multimedia in the computer industry , the confusion of consumers, and the lack of understanding of technology in the human context provide an impetus for examining and speculating on the future of multimedia. "What can a multimedia technology do?" is not a sufficient question for consumers until we add " for whom" . Both how the relevant technology is likely to develop and how human choices would be made are examined with a focus on historical trend in media technology adoption.

Congenital Left Ventricular Diverticulum (선천성 좌심실 게실 1례)

  • Kim, Jong-Young;Kim, Jung-Ho;Jun, Jin-Gon
    • Journal of Yeungnam Medical Science
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    • v.7 no.2
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    • pp.181-187
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    • 1990
  • Congenital diverticulosis of the left ventricle is an extremely rare maldevelopment. We report a 9 year old girl with probable isolated left ventricular diverticulum in whom the diagnosis was made by cross sectional echocardiography and by angiography.

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Neural Model Predictive Control for Nonlinear Chemical Processes

  • Song, Jeong-Jun;Park, Sunwon
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 1993.06a
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    • pp.899-902
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    • 1993
  • A neural model predictive control strategy combining a neural network for plant identification and a nonlinear programming algorithm for solving nonlinear control problems is proposed. A constrained nonlinear optimization approach using successive quadratic programming combined with neural identification network is used to generate the optimum control law for complex continuous chemical reactor systems that have inherent nonlinear dynamics. The neural model predictive controller (MNPC) shows good performances and robustness. To whom all correspondence should be addressed.

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