• Title/Summary/Keyword: window effects

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Analysis of Windowing Effects in the Estimation of Beat Frequencies (비트 주파수 추정에서의 윈도잉 효과 분석)

  • Lee, Jong-Gil
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2010.05a
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    • pp.668-670
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    • 2010
  • It is necessary to estimate the range and Doppler shifted spectrum for the extraction of useful information from the return echoes in the frequency modulated continuous wave radar systems used for the remote sending purpose such as detection of moving targets. However, the spectrum estimation using the FFT method causes the very large sidolobes of clutter masking the essential signal information if the acquisition time of an echo signal is pretty short. Therefore, in this paper, the efficient data windowing method is investigated to suppress the strong sidelobe levels of the clutter and results are analyzed.

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Preparation and Characterization of $Pd/CeO_2/Ta/Si$ model catalysts

  • 김도희;우성일
    • Proceedings of the Korean Vacuum Society Conference
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    • 2000.02a
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    • pp.145-145
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    • 2000
  • M-CeO2 (M : noble metal) catalysts have been widely studied as three-way catalysts and methanol synthesis catalysts. Ceria is thought to play a number of roles in these catalysts. The Ce(IV)/Ce(III) redox pair may store/release gases under oxidizing/reducing conditions, extending the operational window. Additionally, metal-ceria interactions lead to several effects, including the dispersion of the active components and promoting the activation of molecules such as CO or NO. Pd is a promising component to current TWC formulations and behaves particularly well when compared with Pt and Rh-based catalysts for low-temperature oxidation of Co and hydrocarbon. However the effect of Pd-ceria interactions on the physicochemical properties of Pd and the redox properties of Ce is not elucidated yet. In order to know exactly about the metal-ceria interactions, the model study are expecting to give a better environment, resulting in the wide use of the surface science tools. The substrate was Si(100) wafer, on which Ta metal was sputtered as a thickness of 100nm. The CeO2 thin film of 30nm was deposited by using the magnetron sputtering. Spin coating and magnetron sputtering methods were used to make the Pd thin film layer. The prepared sample was investigated by in-situ XPS, AES, SEM and AFM analysis.

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Future Cancer Therapy with Molecularly Targeted Therapeutics: Challenges and Strategies

  • Kim, Mi-Sook
    • Biomolecules & Therapeutics
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    • v.19 no.4
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    • pp.371-389
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    • 2011
  • A new strategy for cancer therapy has emerged during the past decade based on molecular targets that are less likely to be essential in all cells in the body, therefore confer a wider therapeutic window than traditional cytotoxic drugs which mechanism of action is to inhibit essential cellular functions. Exceptional heterogeneity and adaptability of cancer impose significant challenges in oncology drug discovery, and the concept of complex tumor biology has led the framework of developing many anticancer therapeutics. Protein kinases are the most pursued targets in oncology drug discovery. To date, 12 small molecule kinase inhibitors have been approved by US Food and Drug Administration, and many more are in clinical development. With demonstrated clinical efficacy of bortezomib, ubiquitin proteasome and ubiquitin-like protein conjugation systems are also emerging as new therapeutic targets in cancer therapy. In this review, strategies of targeted cancer therapies with inhibitors of kinases and proteasome systems are discussed. Combinational cancer therapy to overcome drug resistance and to achieve greater treatment benefit through the additive or synergistic effects of each individual agent is also discussed. Finally, the opportunities in the future cancer therapy with molecularly targeted anticancer therapeutics are addressed.

Fracture Behavior of AZ31-xCa (x=0, 0.7, 2.0 wt.%) Extrudes during Compression (AZ31-xCa (x=0, 0.7, 2.0 wt.%) 압출재의 압축변형시 파괴거동)

  • Kang, Na Eun;Yim, Chang Dong;You, Bong Sun;Park, Ik Min
    • Korean Journal of Metals and Materials
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    • v.48 no.1
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    • pp.85-89
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    • 2010
  • The plastic deformation behavior of magnesium alloy is affected simultaneously by deformation temperature and strain rate under warm and/or hot working conditions. The soundness of deformation of AZ31-xCa (x=0. 0.7, 2.0 wt.%) extrudes during compression was strongly affected by processing variables including deformation temperature, strain rate. compression-loading direction, which was related to the activation of available deformation systems. The deformation behavior of AZ31-xCa extrudes was also affected by Ca content, which was related to the change of the sort and fraction of second phase. The complex effects of deformation temperature and strain rate on the deformation behavior of AZ31-xCa extrudes during compression under various conditions could be successfully described by Zener-Hollomon parameter.

Thermal Performance Evaluation of Movable Insulation System in Apartments (공동주택 발코니창에 설치된 가동단열 시스템의 열성능 평가)

  • Yoon, Jong-Ho;Kim, Byoung-Soo
    • Journal of the Korean Solar Energy Society
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    • v.28 no.5
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    • pp.28-35
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    • 2008
  • The aim of this study was to analysis the Heating/cooling performance of movable insulation system built in apartments. The process of this study is as follows: 1) Test-cells of movable insulation are designed through the investigation of previous paper and work. The type of the movable insulation used in test-cell is low emissivity(5%) insulation, measured for heating season and the thermal effects are analyzed. 2) The simulation program(Design Builder) was used in energy performance analysis. the reference model of simulation was made up to analysis energy performance on movable insulation system. 3) Selected reference model(Floors:15, Area of Unit:115.5$m^2$) for heating/cooling energy analysis, Energy performance simulation with various variants, such as slate angle of movable insulation(5$^{\circ}$, 30$^{\circ}$, 50$^{\circ}$) and position of movable insulation. Consequently, When movable insulation system is equipped with balcony window of Apartment, Annual heating energy of reference model was cut down at the average of 5.4kWh/$m^2$ or 4.6% of heating/cooling energy.

University Hospital, Which is Based on an Integrated Health Education and Health-care and Family Factors on the Level of Learning Transfer System Inventory (학교기업병원을 기반으로 한 보건통합교육이 보건-의료계열 대학생의 학습전이 요인 및 수준에 미치는 영향)

  • Lee, Jae-Hong;Kim, Gi-Chul;Jeon, Kwon-Il;Lee, Jin-Hwan;Min, Dong-Ki;Kim, In-Gyu
    • PNF and Movement
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    • v.11 no.2
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    • pp.77-85
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    • 2013
  • Purpose : The purpose of this study is to investigate the effects school business hospital-based integrated health education on learning transfer factor and level. Methods : This study conducted a questionnaire survey of 60 students at D college using metastatic diagnostic tool who took the integrated health education curriculum, statistical analysis utilized the SPSS 17.0 for window version. Results : On comparison of the details 5 clauses, 29 questions using LTSI, this study found that the integrated health education based on the school business hospital is effective for learning transfer. Conclusion : What the integrated health education based on clinic practice system at D college to overcome the limitations of health and medical line is effective for learning transfer and it will be useful to cultivate professional.

The Influence that the Closed Chain Breathing Exercise Affects on Thorax Circumference Increase and ROM of Shoulder Rotation on the Cervical Vertebral Cord Injury Patients (닫힌 사슬 호흡 운동법이 상위 경수 손상 환자의 흉곽둘레길이와 어깨관절의 회전가동범위에 미치는 영향)

  • Maeng, Gwan-Cheol;Lee, Byung-Ki;Yun, Jeung-Hyun;Hwang, Sang-Su;Choi, Kwang-Yong
    • PNF and Movement
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    • v.11 no.2
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    • pp.87-93
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    • 2013
  • Purpose : The purpose of this study was to investigate the effects of closed chain breathing exercise on thorax circumference increase and ROM of shoulder rotation for cervical vertebral cord injury patient's. Methods : 12 cervical vertebral cord injury patients volunteer to participate in this study. closed chain breathing exercise group of 4 subjects performed exercise three time a week. The deep breathing exercise group and general exercise group of 4 subjects performed exercise three time a week. We analyaed the descriptive statistics and $3{\times}2$ repeated measures ANOVA by SPSS 12.0 for window. Results : In comparison of rotation of shoulder ROM between pre and post value, the increase of rotation ROM of shoulder was significant in the closed chain breathing exercise group(p<.05). Conclusion : The closed chain breathing exercise helped to increased rotation ROM of shoulder.

First-principles investigation of the monoclinic NaMnO2 cathode material for rechargeable Na-ion batteries

  • Zhang, Renhui;Lu, Zhibin;Yang, Yingchang;Shi, Wei
    • Current Applied Physics
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    • v.18 no.11
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    • pp.1431-1435
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    • 2018
  • Using first-principles calculations, we successfully investigate the electrochemical performance of the monoclinic $NaMnO_2$ for the sodium ion batteries. $NaMnO_2$ possesses a voltage window of 3.54-2.52 V and theoretical reversible capacity of $136mAh\;g^{-1}$. Besides, we find that the metallicity of the monoclinic $NaMnO_2$ gradually increases during Na extraction. Moreover, the computational Na migration energy barrier in the monoclinic $NaMnO_2$ is 0.18 eV, ensuring ideal conductivity and reversible capacity. Although the Jahn-Teller distortion effects limit the enhancement of the reversible capacity of the monoclinic $NaMnO_2$, it is still a right cathode material for the sodium ion batteries. The computational results are well in consistent with the experimental investigations.

Change reaction of fatigue recovery material before and after taping during isokinetic exercise

  • CHOI, Seung-Chul;LEE, Sang-Ho;KIM, Jun-Su
    • The Korean Journal of Food & Health Convergence
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    • v.7 no.3
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    • pp.25-32
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    • 2021
  • This study examined the effects of kinesio taping on recovery from fatigue induced by an exercise of concentric contraction using an isokinetic machine. The fatigue was introduced by a mode of exercise at 60°/sec, 50 repetitions for three sessions. The changes of blood ammonia, lactate, LDH, and CK as a marker of fatigue were monitored. Eight healthy collegiate students participated in two experiments; 1) kinesio taping application condition and 2) no kinesio taping application condition. Before experiments, their physical characteristics were measured. For the experiment, blood samples were taken before and immediately after exercise, and 24hr as well as 72hr of recovery period. Window SPSS package 12.0 version was used and one-way ANOVA with repeated measures were employed. The results were as follows. 1) Blood ammonia tended to reduce along the recovery, but no differences between conditions were noticed. 2) Blood lactate tended to reduce during the recovery period, but differences between conditions were not noticed. 3) The LDH was not different between conditions and CK tended to reduce during the recovery period, but differences between conditions were not noticed. Based on the results, kinesio taping did not influence on recovery phase of blood ammonia, lactate concentration, LDH, and CK.

Quantitative risk assessment for wellbore stability analysis using different failure criteria

  • Noohnejad, Alireza;Ahangari, Kaveh;Goshtasbi, Kamran
    • Geomechanics and Engineering
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    • v.24 no.3
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    • pp.281-293
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    • 2021
  • Uncertainties in geomechanical input parameters which mainly related to inappropriate data acquisition and estimation due to lack of sufficient calibration information, have led wellbore instability not yet to be fully understood or addressed. This paper demonstrates a workflow of employing Quantitative Risk Assessment technique, considering these uncertainties in terms of rock properties, pore pressure and in-situ stresses to makes it possible to survey not just the likelihood of accomplishing a desired level of wellbore stability at a specific mud pressure, but also the influence of the uncertainty in each input parameter on the wellbore stability. This probabilistic methodology in conjunction with Monte Carlo numerical modeling techniques was applied to a case study of a well. The response surfaces analysis provides a measure of the effects of uncertainties in each input parameter on the predicted mud pressure from three widely used failure criteria, thereby provides a key measurement for data acquisition in the future wells to reduce the uncertainty. The results pointed out that the mud pressure is tremendously sensitive to UCS and SHmax which emphasize the significance of reliable determinations of these two parameters for safe drilling. On the other hand, the predicted safe mud window from Mogi-Coulomb is the widest while the Hoek-Brown is the narrowest and comparing the anticipated collapse failures from the failure criteria and breakouts observations from caliper data, indicates that Hoek-Brown overestimate the minimum mud weight to avoid breakouts while Mogi-Coulomb criterion give better forecast according to real observations.