• Journal of Ginseng Research
• /
• 제40권3호
• /
• pp.245-250
• /
• 2016

Background: Ginsenosides are the major effective ingredients responsible for the pharmacological effects of ginseng. Malonyl ginsenosides are natural ginsenosides that contain a malonyl group attached to a glucose unit of the corresponding neutral ginsenosides. Methods: Medium-pressure liquid chromatography and semipreparative high-performance liquid chromatography were used to isolate purified compounds and their structures determined by extensive one-dimensional- and two-dimensional nuclear magnetic resonance (NMR) experiments. Results: A new saponin, namely malonyl-ginsenoside Re, was isolated from the fresh flower buds of Panax ginseng, along with malonyl-ginsenosides Rb1, Rb2, Rc, Rd. Some assignments for previously published $^1H$- and $^{13}C$-NMR spectra were found to be inaccurate. Conclusion: This study reports the complete NMR assignment of malonyl-ginsenoside Re, $Rb_1$, $Rb_2$, Rc, and Rd for the first time.

• 한국임상수의학회지
• /
• 제21권2호
• /
• pp.122-128
• /
• 2004

This research was conducted to investigate the actual condition of injured wild animals in Gangwon-do between January and December in 2002. The subject of this study was the wounded wild animals on the receipt of the governmental and the civil organizations for medical treatment. Especially, the natural monuments among the wounded were included in this research. 363 cases in birds and 274 cases in mammals were saved from injuries. In the case of the natural monuments, 140 and 7 cases got help in birds and mammals, respectively. Wild animals were injured particularly in summer and the ultimate causes were trauma and dehydration. More than 50% out of the animals under medical treatment from the organizations were dead. It was clear that most causes of the animal injuries were artificial owing to the breakdown of the ecosystem. Consequently, the consistent observation on the control system of the wild animals will be needed. And it will be also necessary to increase research works and the nationwide public city activities on the wild animals.

• Journal of Ginseng Research
• /
• 제42권1호
• /
• pp.27-34
• /
• 2018

Background: The use of different methods for the processing of ginseng can result in alterations in its medicinal properties and efficacy. White ginseng (WG), frozen ginseng (FG), and red ginseng (RG) are produced using different methods. WG, FG, and RG possess different pharmacological properties. Methods: WG, FG, and RG extracts and pure ginsenosides were administered to rats to study the pharmacokinetics and tissue distribution characteristics of the following ginsenosides-DRg1, Re, Rb1, and Rd. The concentrations of the ginsenosides in the plasma and tissues were determined using UPLC-MS/MS. Results: The rate and extent of absorption of Rg1, Re, Rb1, and Rd appeared to be affected by the different methods used in processing the ginseng samples. The areas under the plasma drug concentration-time curves (AUCs) of Rg1, Re, Rb1, and Rd were significantly higher than those of the pure ginsenosides. In addition, the AUCs of Rg1, Re, Rb1, and Rd were different for WG, FG, and RG. The amounts of Rg1, Re, Rd, and Rb1 were significantly (p < 0.05) higher in the tissues than those of the pure ginsenosides. The amounts of Re, Rb1, and Rd from the RG extract were significantly higher than those from the WG and FG extracts in the heart, lungs, and kidneys of the rats. Conclusion: Our results show that the use of different methods to process ginseng might affect the pharmacokinetics and oral bioavailability of ginseng as well as the tissue concentrations of Rg1, Re, Rd, and Rb1.

• 대한수의학회지
• /
• 제17권1호
• /
• pp.17-26
• /
• 1977

Parasites of wild animals are closely related with parasites of domestic animals. Wild animals take charge of an important role at parasitic infestation of domestic animals because of unrestrained movement. The authors carried out the work of actual condition of parasitic infestation on wild animals, total 1,014 cases, in the Korean Zoo. The results are summarized as follows: 1. Total rate of parasitic infestation was 36.1% with infestation of 366 among 1,014 cases. The rate of single infestation was 32.6% with infestation of 331 cases, double infestation 3.1% with 31 cases, triple infestation 0.2% with 2 cases and quadrople infestation 0.2% with 2 cases. 2. The parasites on the zoo animals were identified as follows: Lion: Sarcoptiform, Toxocara sp., Toxascaris leonina, Ancylostoma sp. and Isospora spp. Puma: Toxocara sp., Ancylostoma sp. and Isospora sp. Leopard: Toxocara spp., Ancylostoma sp., Trichuris sp., Dibothriocephalus sp. and Physaloptera sp. Wolf: Sarcoptiform and Dibothriocephalus spp. Fox: Trichuris sp., Capillaria aerophila, Spirocerca sp., Paragonimas kellicotti. Jackal: Sarcoptiform, Ascaris sp. and Echinococcus granulosus. Wild Cat: Dibothriocephalus sp. Tiger: Toxascaris leonina. Bear: Sarcoptiform, Metastrongylus apri, Ancylostoma sp. and Ascaris sp. Raccoon and Raccoon dog: Sarcoptiform, Paragonimus kelliotti, and Isospora sp. Boar: Oesophagostomum spp. and Eimeria spp. Mortkey: Sarcoptiform, Trichuris sp., Physaloptera spp.. Enterobius sp. and Isospora sp. Elephant: Sarcoptiform, Strongyloides sp. and Strongylus spp. Deer: Sarcoptiform, Strongyloides sp., Trichuris ovis, Mccistocirrus digitatus, Haemonchus sp., Oesophagostomum radiatum, Paramphistornum spp., Bunostomum phlebotomum, Fasciola hepatica and Eimeria spp. Bison: Sarcoptiform, Haernonchus sp., Marshallagia sp., Nematodirus sp. and Eimeria sp. Zebra: Strongylus sp. and Parascaris equorum. Goral and Barbary: Sarcoptiform, Haemonchus sp., Oesophagostomum venulosum, Moniezia sp. and Eimeria spp. Lama: Strongyloides sp. and Haemonchus sp. Kangaroo: Strongyloides sp. and Haemonchus sp. Camel: Strongyloides sp., Trichuris ovis and Eimeria sp. Peacock and the Other Birds: Sarcoptiform, Capillaria contorta, Capillaria caudinflata, Ascaridia spp., Heterakis spp., Hymenolepis sp., Eimeria spp., Histomonas, Ornithionyssus bacoti, Macrochelidae and Trichomonas. 3. Among the zoo animals, wild carnivora were infestated with the parasites which are common parasites of dogs and cats, wild herbivora were infestated with the parasites of herbivora domestic animals. and wild fowls were infestated with the parasites of domestic fowls.

• 한국동물위생학회지
• /
• 제43권1호
• /
• pp.31-37
• /
• 2020

Clostridial bacteria are zoonotic agents, which cause severe necrotizing enteritis, pseudo-membrane colitis, enterotoxemia to both humans and animals. The objective of this study was to monitor the antibiotic resistance of Clostridium isolates on clinical specimens from wild animals in Seoul zoo for 5 years. Clostridium isolates were verified by using Vitek2 compact machine. Antibiotic susceptibility was assessed by antibiotic disc diffusion test, which was followed by Kirby-Bauer disc diffusion test method. The frequency of Antimicrobial resistance of Clostridium isolate was the greatest in gentamicin (87%), then in order of amikacin (80%). There were 55.6% of Clostridium isolates showed multiple drug resistance (MDR). These results showed that a lot of Clostridial bacteria from wild animals in Seoul zoo were acquired antibiotic resistance. Because of the wild animal's aggressive manner, it has been hard to collect clinical samples from wild animals in a zoo to exam antibiotic susceptibility. For these reasons, empirical use of antibiotics has been performed in frequently. It may cause to increase the emergence of antibiotic resistance bacteria. In addition, the antibiotic resistance bacteria from zoo animals can be spread to other wild animals which inhabit around the zoo. Therefore, regular monitoring of antibiotic resistance Clostridial bacteria is important to protect animals and humans from Clostridial diseases.

• Journal of Forest and Environmental Science
• /
• 제29권1호
• /
• pp.90-98
• /
• 2013

The purpose of this study was to understand the geographical and environmental distribution of wild animals in Baekdudaegan region using field survey and GIS data. Crucial factors were selected and analyzed to understand the distributional characteristics of wild animals (7 species in 6 families) and rare endemic plants (14 species in 11 families). These crucial factors include stand factors (forest type, DBH class, and crown density), soil factors (bed rock, soil texture, and organic matter), geographical factors (elevation, slope, aspect) and climatic factors (temperature, rain fall, humidity). Finally, 10 factors were selected by statistical analysis and categorized for analyzing geographical and environmental features. Four families such as Muridae, Sciuridae, Suidae and Talpidea in wild animal showed the similar habitat characteristics with the 10 factors.

• 한국정보통신학회:학술대회논문집
• /
• 한국정보통신학회 2019년도 춘계학술대회
• /
• pp.306-309
• /
• 2019

매년 멧돼지, 고라니 등의 야생동물로 인한 농가의 피해가 증가하지만 현 시스템은 정부 측 포수들이 직접 야간에 총과 손전등을 이용해 동물들을 찾아다니며 포획하는 상황이다. 이는 시간적으로 매우 비효율적이며 피해 받는 즉시 즉각적인 조치가 불가능하다. 이에 본 논문에서는 야간에도 동물이나 사람을 인식 할 수 있는 열화상 카메라와 딥러닝을 사용한 적외선카메라를 이용해 야생동물을 탐지하고 쫓아내거나 빠르게 포획 할 수 있는 시스템에 대해서 소개하고자 한다.

• Toxicological Research
• /
• 제17권
• /
• pp.305-307
• /
• 2001

Toluene diisocyanate (TDI) is widely used in the manufacture of polyurethanes and is a recognized cause of occupational asthma. Although extensive investigations have been undertaken, the molecular mechanism(s) of the disease is still unclear. We hypothesized that inflammatory cytokines are required during both the sensitization and elicitation phases of the disease and have utilized TNF-R knock-out (KO) mice to address the hypothesis. Black C57 TNFR knock-out mice were exposed to TDI by sc injection and challenged by inhalation of 100 ppb TDI vapor. Control animals included: wild type C57 animals, sham-exposed animals that were challenged with TDI, and animals that were injected with anti-TNF antibodies prior to sensitization and again prior to challenge. Total IgE was increased in the knock-out animals compared with the wild type sensitized and challenged animals whereas TDI-specific IgG antibodies did not differ significantly in KO and wild type animals. There was less inflammation in the nares and trachea in KO animals compared with the wild type animals exposed to TD1 as well as less goblet cell hyperplasia and epithelial damage. Airway reactivity was assessed in animals treated with anti-TNF$\alpha$ antibody and found to be substantially reduced compared with that in sensitized and challenged animals. These results indicate that TNF$\alpha$ plays a role in the immunologic and physiologic responses and in airways inflammation in this animal model and suggests a role for TNF in occupational asthma due to TDI.

• 한국전자통신학회논문지
• /
• 제5권6호
• /
• pp.575-580
• /
• 2010

본 연구는 야생동물의 도로 진입방지를 위한 시스템으로, 제안 시스템을 구성하고 있는 적외선 센서와 야생동물이 접근할 때 방지를 위한 발성부와 빛을 발생하는 발광부와 태양열을 이용하여 전원을 공급하는 전원공급부와 외부의 배터리를 이용한 전원공급부와 도로 가장자리에 경계를 알리는 나선에 미세 전류를 통하게 하여 경고 발성이나 발광효과를 극대화하도록 하여 접근하는 야생동물을 제지하는 시스템에 관한 것이다. 본 제안 시스템은 고속도로, 국도, 지방도와 같은 야생동물이 자주 출몰하는 도로 주변에 설치하여 주야간을 막론하고 출몰하는 야생동물의 진입을 방지하여 동물이 차량과 충돌하는 피해를 예방하며, 더불어 운전자를 보호하며 자연환경의 생태계를 보존하는데 있다.

• Parasites, Hosts and Diseases
• /
• 제51권3호
• /
• pp.379-381
• /
• 2013

To know the status of sparganum (plerocercoid of Spirometra erinacei) infection in the Korean wild life, several species of wild animals were captured in Gangwon-do and examined for their status of infection with spargana. From February to December 2011, a total of 62 wild boars, 5 badgers, 1 weasel, 1 Siberian chipmunk, and 53 wild rodents were captured, and their whole muscles were examined with naked eyes for the presence of spargana worms. From the weasel and 1 wild boar, a total of 5 spargana specimens were extracted. The weasel was for the first time recorded as an intermediate or paratenic/transport host of S. erinacei in Korea, and both the weasel (Mustela sibirica manchurica) and wild boar (Sus scrofa) were added to the list of wild animals carrying spargana.