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Bone regeneration and graft material resorption in extraction sockets grafted with bioactive silica-calcium phosphate composite (SCPC) versus non-grafted sockets: clinical, radiographic, and histological findings

  • Adel-Khattab, Doaa;Afifi, Nermeen S.;el Sadat, Shaimaa M. Abu;Aboul-Fotouh, Mona N.;Tarek, Karim;Horowitz, Robert A.
    • Journal of Periodontal and Implant Science
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    • v.50 no.6
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    • pp.418-434
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    • 2020
  • Purpose: The purpose of the present study was to evaluate the effect of silica-calcium phosphate composite (SCPC) granules on bone regeneration in extraction sockets. Methods: Ten patients were selected for a split-model study. In each patient, bone healing in SCPC-grafted and control ungrafted sockets was analyzed through clinical, radiographic, histomorphometric, and immunohistochemical assessments 6 months postoperatively. Results: A radiographic assessment using cone-beam computed tomography showed minimal ridge dimension changes in SCPC-grafted sockets, with 0.39 mm and 1.79 mm decreases in height and width, respectively. Core bone biopsy samples were obtained 6 months post-extraction during implant placement and analyzed. The average percent areas occupied by mature bone, woven bone, and remnant particles in the SCPC-grafted sockets were 41.3%±12%, 20.1%±9.5%, and 5.3%±4.4%, respectively. The percent areas of mature bone and woven bone formed in the control ungrafted sockets at the same time point were 31%±14% and 24.1%±9.4%, respectively. Histochemical and immunohistochemical analyses showed dense mineralized bundles of type I collagen with high osteopontin expression intensity in the grafted sockets. The newly formed bone was well vascularized, with numerous active osteoblasts, Haversian systems, and osteocytes indicating maturation. In contrast, the new bone in the control ungrafted sockets was immature, rich in type III collagen, and had a low osteocyte density. Conclusions: The resorption of SCPC granules in 6 months was coordinated with better new bone formation than was observed in untreated sockets. SCPC is a resorbable bone graft material that enhances bone formation and maturation through its stimulatory effect on bone cell function.

Control of the VIV of a cantilevered square cylinder with free-end suction

  • Li, Ying;Li, Shiqing;Zeng, Lingwei;Wang, Hanfeng
    • Wind and Structures
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    • v.29 no.1
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    • pp.75-84
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    • 2019
  • A steady slot suction near the free-end leading edge of a finite-length square cylinder was used to control its aerodynamic forces and vortex-induced vibration (VIV). The freestream oncoming flow velocity ($U_{\infty}$) was from 3.8 m/s to 12.8 m/s. The width of the tested cylinder d = 40 mm and aspect ratio H/d = 5, where H was the height of the cylinder. The corresponding Reynolds number was from 10,400 to 35,000. The tested suction ratio Q, defined as the ratio of suction velocity ($U_s$) at the slot over the oncoming flow velocity at which the strongest VIV occurs ($U_{\nu}$), ranged from 0 to 3. It was found that the free-end slot suction can effectively attenuate the VIV of a cantilevered square cylinder. In the experiments, the RMS value of the VIV amplitude reduced quickly with Q increasing from 0 to 1, then kept approximately constant for $Q{\geq}1$. The maximum reduction of the VIV occurs at Q = 1, with the vibration amplitude reduced by 92%, relative to the uncontrolled case. Moreover, the overall fluctuation lift of the finite-length square cylinder was also suppressed with the maximum reduction of 87%, which occurred at Q = 1. It was interesting to discover that the free-end shear flow was sensitive to the slot suction near the leading edge. The turbulent kinetic energy (TKE) of the flow over the free end was the highest at Q = 1, which may result in the strongest mixing between the high momentum free-end shear flow and the near wake.

Efficacy of Blanket Vegetation Mats on Soil and Native Groundcover Plants under Treatment of High Concentration Deicing Salt (고농도 제설제 처리에서 토양 및 자생 초화류에 미치는 Blanket 식생매트의 효용성)

  • Ju, Jin Hee;Lee, Je Man;Kim, Won Tae;Lim, Byung Ok;Seo, Nam Kyu;Yoon, Yong Han
    • Journal of Environmental Science International
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    • v.31 no.3
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    • pp.247-254
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    • 2022
  • This study investigated the effect of vegetation mat on plant growth and salt reduction in the soil treated with high concentration deicing salt. In order to measure soil chemical characteristics and plant growth, three native groundcover plants (Dendranthema zawadskii var. latilobum, Dendranthema boreale, and Kalimeris yomena) were grown in each of the three plastic containers (50.0 cm width × 35.0 cm length × 8.5 cm deep) with a high concentration treatment of calcium chloride deicing salt. There were two treatments: control, and BVM that combines B (blanket) and VM (vegetation mat). 1,600 g of soil was placed on the top of the drainage layer with 290 g of perlite, 100 seeds each of the three native plants with three repetitions were sowed, and 10 g/L of calcium chloride deicing salt was added in the treatment. As a result of the chemical properties of soil, soil in control treatment was acidic and soil electrical conductivity in BVM was the lowest. Also, exchangeable cations (K+, Ca2+, Na+, and Mg2+) in soil and all the three plants were significantly decreased in the BVM treatment. Meanwhile, the germination rate of Dendranthema zawadskii var. latilobum was the highest under high concentration deicing salt in compared to the two plants. Overall, three native groundcover plant growth was higher in the BVM than control treatment significantly. These results suggest that the treatment of blanket vegetation mat has a positive effect on soil and plant growth in soil damaged by deicing salt.

Effects of 4-hexylresorcinol on facial skeletal development in growing rats: Considerations for diabetes

  • Hannah Jeong;Jwa-Young Kim;Xiangguo Che;Je-Yong Choi;Insan Jang;Seong-Gon Kim
    • The korean journal of orthodontics
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    • v.53 no.6
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    • pp.393-401
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    • 2023
  • Objective: To investigate the long-term effects of 4-hexylresorcinol (4HR) on facial skeletal growth in growing male rats, with a focus on diabetic animal models. Methods: Forty male rats were used. Of them, type 1 diabetes mellitus was induced in 20 animals by administering 40 mg/kg streptozotocin (STZ), and they were assigned to either the STZ or 4HR-injected group (STZ/4HR group). The remaining 20 healthy rats were divided into control and 4HR groups. We administered 4HR subcutaneously at a weekly dose of 10 mg/kg until the rats were euthanized. At 16 weeks of age, whole blood was collected, and microcomputed tomography of the skull and femur was performed. Results: All craniofacial linear measurements were smaller in the STZ group than in the control group. The mandibular molar width was significantly smaller in the 4HR group than in the control group (P = 0.031) but larger in the STZ/4HR group than in the STZ group (P = 0.011). Among the diabetic animals, the STZ/4HR group exhibited significantly greater cortical bone thickness, bone mineral density, and bone volume than the STZ group. Serum testosterone levels were also significantly higher in the STZ/4HR group than in the STZ group. Conclusions: 4HR administration may have divergent effects on mandibular growth and bone mass in healthy and diabetic rats. In the context of diabetes, 4HR appears to have beneficial effects, potentially through the modulation of mitochondrial respiration.

Effect of Planting Patterns on the Cultivation of Eggplant (Solanum melongena) and Marigold (Tagetes erecta) for the Activation of Eco-Friendly Rooftop Urban Agriculture (친환경 옥상 도시농업 활성화를 위한 배식모형에 따른 가지(Solanum melongena)와 메리골드(Tagetes erecta) 식재효과)

  • Jae-Hyun Park;Sang-Il Seo;Deuk-Kyun Oh;Yong-Han Yoon;Jin-Hee Ju
    • Journal of Environmental Science International
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    • v.33 no.6
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    • pp.417-425
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    • 2024
  • This study investigated the effects of various planting models on the joint cultivation of eggplant (Solanum melongena) and marigold (Tagetes erecta)to enhance sustainable rooftop urban farming. Rooftop agriculture is increasingly valued to boost the food supply and benefit the environment. Integrating such practices into urban planning is viewed as a way to sustainably manage resources and improve the food-energy-water cycle in cities. The experiment was conducted on a rooftop in Chungju, South Korea from May to August. Four different planting setups were used: central eggplant with peripheral marigold (SET), eggplant with a protective net (SIC), central marigold with peripheral eggplant (TES), and control with only eggplant (CON S). These models tested the effects of companion planting versus monoculture using a lightweight soil mix ideal for rooftops made from cocopeat and perlite and enriched with organic fertilizer. Measurements focused on soil conditions and plant health and assessed soil temperature, moisture, conductivity, plant height, width, and leaf size. The results indicated that the SET modelyielded the best growth. This setup benefited from marigold pest control properties and its ability to improve soil conditions by enhancing moisture and nutrient levels and aiding eggplant growth. These findings underscore the potential of mixed planting on rooftops and suggest that such approaches can be effectively incorporated into urban agriculture to boost yield and environmental sustainability. This study supports the idea that diverse planting methods can significantly affect plant growth and promote urban greening and food security.

Multi-scale calibration of a line-style sand pluviator

  • Yifan Yang;Dirk A. de Lange;Huan Wang;Amin Askarinejad
    • Geomechanics and Engineering
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    • v.37 no.5
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    • pp.431-441
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    • 2024
  • A newly developed line-style sand pluviator has been calibrated to prepare repeatable sand specimens of specific statuses of compactness and homogeneity for laboratory tests. Sand is falling via a bottom slot of a fixed hopper, and by moving the sample container under the slot, the container is evenly filled with sand. The pluviator is designed with high flexibility: The falling height of sand, the hopper's opening width and the relative moving speed between the hopper and the sample box can be easily adjusted. By changing these control factors, sand specimens of a wide range of densities can be prepared. A series of specimen preparation was performed using the coarse Merwede River sand. Performance of the pluviator was systematically evaluated by exploring the alteration of achievable density, as well as checking the homogeneity and fabric of the prepared samples by CT scanning. It was found that the density of prepared coarse sand samples has monotonic correlations with none of the three control factors. Furthermore, CT scanning results suggested that the prepared samples exhibited excellent homogeneity in the horizontal direction but periodical alteration of density in the vertical direction. Based on these calibration test results, a preliminary hypothesis is proposed to describe the general working principles of this type of pluviators a priori, illustrating the mechanisms dominating the non-monotonic correlations between control factors and the relative density as well as the vertically prevalent heterogeneity of specimens. Accordingly, practical recommendations are made in a unified framework in order to lessen the load of similar calibration work.

Field Survey of Greenhouse for Strawberry Culture -Case Study Based on Western Gyeongnam Area- (딸기재배 온실의 현장조사 분석 -서부경남 지역을 중심으로-)

  • Jeong, Young Kyun;Lee, Jong Goo;Yun, Sung Wook;Kim, Hyeon Tae;Yoon, Yong Cheol
    • Journal of Bio-Environment Control
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    • v.27 no.3
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    • pp.253-259
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    • 2018
  • This study set out to select a system to realize an optimal environment for strawberry cultivation greenhouses based on data about the growth and development of strawberry and its environment and to provide basic data for the research of its improved productivity. For these purposes, the investigator conducted a field survey with greenhouses for strawberry cultivation in western Gyeongnam. The findings show that farmers in their fifties and sixties accounted for the biggest part in the age groups of strawberry farmers. While those who were under 50 were accounted for approximately 67.5%, those who were 60 or older accounted for 32.5%. As for cultivation experiences, the majority of the farmers had ten years of cultivation experiences or less with some having 30 years of cultivation experiences or more. All the farmers built an arch type single span greenhouse. Those who used nutrient solutions were about 75.0%, being more than those who used soil. All of the farmers that used a nutrient solution adopted an elevated hydroponic system. The single span greenhouses were in the range of 7.5~8.5m, 1.3~1.8m and 2.5~3.5m for width, eaves, and ridge height, respectively, regardless of survey areas. The rafters interval was about 0.7~0.8m. In elevated hydroponic cultivation, the width, height, and interval of the beds were about 0.25m, 1.2m and 1.0m, respectively. As for the strawberry varieties, the domestic ones accounted for approximately 97.5% with Seolhyang being the most favorite one at about 65.0%. As for the internal environment factors of greenhouses, 38 farmers measured only temperature and relatively humidity. As for hydroponics, the farmers used a hydroponics control system. Except for the farmers that introduced a smart farm system for temperature and humidity control, approximately 85.0% controlled temperature and humidity only with a control panel for side windows and ventilation fans. As for heating and heat insulation, all of the farmers were using water curtains with many farmers using an oil or electric boiler, radiating lamp or non-woven fabric, as well, when necessary.

Plasma Etching Process based on Real-time Monitoring of Radical Density and Substrate Temperature

  • Takeda, K.;Fukunaga, Y.;Tsutsumi, T.;Ishikawa, K.;Kondo, H.;Sekine, M.;Hori, M.
    • Proceedings of the Korean Vacuum Society Conference
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    • 2016.02a
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    • pp.93-93
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    • 2016
  • Large scale integrated circuits (LSIs) has been improved by the shrinkage of the circuit dimensions. The smaller chip sizes and increase in circuit density require the miniaturization of the line-width and space between metal interconnections. Therefore, an extreme precise control of the critical dimension and pattern profile is necessary to fabricate next generation nano-electronics devices. The pattern profile control of plasma etching with an accuracy of sub-nanometer must be achieved. To realize the etching process which achieves the problem, understanding of the etching mechanism and precise control of the process based on the real-time monitoring of internal plasma parameters such as etching species density, surface temperature of substrate, etc. are very important. For instance, it is known that the etched profiles of organic low dielectric (low-k) films are sensitive to the substrate temperature and density ratio of H and N atoms in the H2/N2 plasma [1]. In this study, we introduced a feedback control of actual substrate temperature and radical density ratio monitored in real time. And then the dependence of etch rates and profiles of organic films have been evaluated based on the substrate temperatures. In this study, organic low-k films were etched by a dual frequency capacitively coupled plasma employing the mixture of H2/N2 gases. A 100-MHz power was supplied to an upper electrode for plasma generation. The Si substrate was electrostatically chucked to a lower electrode biased by supplying a 2-MHz power. To investigate the effects of H and N radical on the etching profile of organic low-k films, absolute H and N atom densities were measured by vacuum ultraviolet absorption spectroscopy [2]. Moreover, using the optical fiber-type low-coherence interferometer [3], substrate temperature has been measured in real time during etching process. From the measurement results, the temperature raised rapidly just after plasma ignition and was gradually saturated. The temporal change of substrate temperature is a crucial issue to control of surface reactions of reactive species. Therefore, by the intervals of on-off of the plasma discharge, the substrate temperature was maintained within ${\pm}1.5^{\circ}C$ from the set value. As a result, the temperatures were kept within $3^{\circ}C$ during the etching process. Then, we etched organic films with line-and-space pattern using this system. The cross-sections of the organic films etched for 50 s with the substrate temperatures at $20^{\circ}C$ and $100^{\circ}C$ were observed by SEM. From the results, they were different in the sidewall profile. It suggests that the reactions on the sidewalls changed according to the substrate temperature. The precise substrate temperature control method with real-time temperature monitoring and intermittent plasma generation was suggested to contribute on realization of fine pattern etching.

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Effect of Using Burn-type CO2 Generators When Cultivation Strawberry in a Greenhouse (딸기재배 시 연소식 탄산가스 발생기 이용 효과 구명)

  • Lee, Jae Han;Lee, Jung Sup;Park, Kyoung Sub;Kwon, Joon Kook;Kim, Jin Hyun;Lee, Dong Soo;Yeo, Kyung Hwan
    • Journal of Bio-Environment Control
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    • v.27 no.2
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    • pp.111-116
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    • 2018
  • This study were carried out to evaluate the efficiency of using burn-type $CO_2$ generators in greenhouse for cultivation 'Seolhyang' strawberry ($Fragaria{\times}ananassa\;Duch.$) during winter season. The concentration of $CO_2$ was 200 to $600{\mu}mol{\cdot}mol^{-1}$ in the control, and 800 to $1,100{\mu}mol{\cdot}mol^{-1}$ in using burn-type $CO_2$ generator between 6 and 11 hours. At other times, it was observed that at similar concentration in the control and using burn-type $CO_2$ generator. Measured greenhouse air temperature inside the of using burn-type $CO_2$ generator was $2{\sim}3^{\circ}C$ higher than the control at 6 ~ 10 am. There was no temperature difference between treatments after 11 o'clock. Plant height, leaf length, leaf width, root diameter, fresh weight, and dry weight were not different between treatments. The marketable yield (kg/10a) of using burn-type generator were 4,131 kg, which was 519 kg higher than the control. Therefore, the total fruit yields increased 17% compared to the control.

A Path-Tracking Control of Optically Guided AGV Using Neurofuzzy Approach (뉴로퍼지방식 광유도식 무인반송차의 경로추종 제어)

  • Im, Il-Seon;Heo, Uk-Yeol
    • Journal of Institute of Control, Robotics and Systems
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    • v.7 no.9
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    • pp.723-732
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    • 2001
  • In this paper, the neurofuzzy controller of optically guided AGV is proposed to improve the path-tracking performance A differential steered AGV has front-side and rear-side optical sensors, which can identify the guiding path. Due to the discontinuity of measured data in optical sensors, optically guided AGVs break away easily from the guiding path and path-tracking performance is being degraded. Whenever the On/Off signals in the optical sensors are generated discontinuously, the motion errors can be measured and updated. After sensing, the variation of motion errors can be estimated continuously by the dead reckoning method according to left/right wheel angular velocity. We define the estimated contour error as the sum of the measured contour in the sensing error and the estimated variation of contour error after sensing. The neurofuzzy system consists of incorporating fuzzy controller and neural network. The center and width of fuzzy membership functions are adaptively adjusted by back-propagation learning to minimize th estimated contour error. The proposed control system can be compared with the traditional fuzzy control and decision system in their network structure and learning ability. The proposed control strategy is experience through simulated model to check the performance.

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