• Title/Summary/Keyword: wide frequency range

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Enhancement of Transdermal Drug Delivery Using Ultrasound (초음파를 이용한 경피약물수송의 촉진)

  • Park, Seung-Kyu;Kim, Tae-Youl
    • The Journal of Korean Physical Therapy
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    • v.13 no.3
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    • pp.719-726
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    • 2001
  • Transdermal drug delivery offers various advantages over conventional drug delivery systems, such as avoidance gastrointestinal degradation and hepatic first-pass effect. encourages patient compliance. and possible sustained release of drugs. However, transdermal transport of drugs is low permeability of the stratum corneum, the superficial layer of the skin. Many physicochemical and biological factors influencing transdermal transport is described together with the corresponding experimental and clinical results. Phonophoresis is medical treatment with drugs introduced into the skin by ultrasound energy. Enhanced drug penetration is through to result from the biophysical alterations of skin structure by ultrasound waves. The frequency used for phonophoresis is usually from 20 kHz to 15MHz. Phonophoresis can be categorized in to three ranges: low-frequency range(below 1 MHz). therapeutic frequency range(1 to 3MHz), and high-frequency range(above 3 MHz). The depth of penetration of ultrasound into skin is inversely proportional to the frequency. Cavitation may cause mechanical stress. temperature elevation, or enhanced chemical reactivity causing drug transport. One theory is that ultrasound affects the permeation of the stratum corneum lipid structure as the limiting step in permeating through the skin. The range of indications for phonophoresis is wide. Aspecific classification of the range of indications is obtained by classification of pathological conditions. The continuous research is needed for many interesting issucs of phonophoretic transdermal delivory in new future.

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Development and characterization of a ultra-wide bandwidth video detector for the UHF partial discharge monitoring system (UHF 부분방전 감시 장치를 위한 초광대역 검출장치 개발 및 특성조사)

  • Park, Ki-Jun;Goo, Sun-Geun;Yoon, Jin-Yul
    • Proceedings of the KIEE Conference
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    • 2002.07c
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    • pp.1649-1651
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    • 2002
  • Ultra-wide bandwidth (UWB) detection method has been widely used as a front end detection scheme for the ultra-high frequency (UHF) partial discharge (PD) monitoring systems. A broad-band video detector module was developed and characterized for the UHF UWB PD detection systems. The useable bandwidth of the module is more than 2 GHz and it is optimized for 50-ohm systems. The detection sensitivity and dynamic range of the module were characterized by using a known ns-width RF pulses of GHz range. The dynamic range is more than 6-decades and the module can detect pulsed RF signals down to 1 nW. The detector module can eliminate expensive equipment such as high speed oscilloscopes and radio frequency (RF) spectrum analyzers. Therefore, it enables one to use slow speed data acquisition systems for the PD monitoring at the UHF range. The detector module was used to detect real PDs of about <3 pC. The module converts the UWB PD signals into a low-bandwidth video signal with a high signal-to-noise ratio.

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Frequency Synthesizer Design for Ultra-Wide Band Receiver (초광대역 수신기용 주파수 합성기 설계)

  • Koo, Bon-San;Lee, Moon-Que;Kim, Hyuk-Je;Hong, Hun-Jin
    • Proceedings of the Korea Electromagnetic Engineering Society Conference
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    • 2003.11a
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    • pp.313-317
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    • 2003
  • In this paper, ultra-wideband frequency synthesizer which operates at S-band ($2{\sim}4GHz$) is designed. Designed frequency synthesizer shows the frequency range of $2.2{\sim}4.0GHz$ and output power of $-2{\sim}3dBm$. Phase noise characteristics are measured below -92.0dBc/hz at 100kHz offset frequency in entire sweep range and lock time is measured below 3.55ms. Spurious level is below -62.33dBc at comparison frequency of 1MHz.

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The Dependence of Temperature and Frequency for the Dissipation Factor in Liquid Dielectrics (액체절연체(실리콘유) 유전정접의 온도및 주파수의존성)

  • 이돈희;소병문;이수원;김왕곤;홍진웅
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1993.11a
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    • pp.85-89
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    • 1993
  • Silicone oil exhibits the properies of both organic and inorganic substances and, thus, it has many superior properties such as higher thermal resistance and lower thermal oxidation level when compared to other dielectric liquids. In order to investigate the dielectric characteristics, dielectric liquids of viscosity 1 [cSt] is chosen as the specimen and experiment is performed in the temperature range of 20∼65 [$^{\circ}C$] and frequency range of 30∼1${\times}$10$\^$6/ [Hz] respectively. As a result, the observed linear decrease in dissipation factor at the frequency range below 3 [kHz] is due to the influence of frequency, whereas the increase in dissipation factor at higher frequency range is contributed by electrode's resistance. At a fixed frequency of 30 [kHz], increasing temperature results in higher peak value and wide width of the absorption curve. This is due to the increase in dipole and viscosity. As temperature increases, dipole moment is decreased from 0.98 to 0.64 [debye]. The activation energy which causes the relaxation and loss of dielectric is obtained about 15 [kcal/mole].

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Analysis of Antenna Impact on Wide-band Indoor Radio Channel and Measurement Results at 1 GHz, 5.5 GHz, 10 GHz and 18 GHz

  • Santella, Giovanni
    • Journal of Communications and Networks
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    • v.1 no.3
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    • pp.166-181
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    • 1999
  • The object of this paper is to investigate the influence of antenna pattern on indoor radio channel characteristics. Different from previous works where this analysis was carried out at a fixed frequency using different antennas, in the present paper (where measurements were taken in a wide frequency range) the variation of the radiation pattern was caused by two factors: the change of the radiation pattern when the same antenna was used at different frequenicies and the use of different type of antennas. To carry out this analysis, frequency domain measurements of the indoor radio channel at 1 GHz, 5.5 GHz, 10 GHz and 18 GHz were collected. Measurements were taken using a network analyzer. Serveral re-alizations of the channel transfer function were obtained varying, for each measurement, the positon of the transmitter and keep-ing the receiver fixed. Estimate of the channel impulse response was obtained from the Inverse Fourier Transform (IFT) of the fre-quency response. The measurements were performed in an office enviroment with mostly metallic walls and inner separations. The obtained data were elaborated to obtain the power versus distance relationship, the Cummulative Distribution Functions(CDFs) of rms Delay Spread(DS) and of the 3 dB frequency correlation band-width. Finally, the 3 dB width of the frequency correlation func-tion has been empirically related to the inverse of the rms DS of the impulse response.

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Development of Underwater Wide-band Acoustic Transducer Using the 1-3 Piezoelectric Composite (1-3형 압전복합체를 이용한 광대역 수중 음향 트랜스듀서 개발)

  • Lee, Kyung-Woo;So, Hyoung-Jong;Lim, Sil-Mook;Kim, Won-Ho;Kim, Dae-Yun
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.18 no.4
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    • pp.424-431
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    • 2008
  • Recently, it is required that acoustic transducers for underwater detection and communication sensor have wide bandwidth and low operating frequency. In this research, the new acoustic transducer is proposed. This transducer is tonpilz type, and made of 1-3 piezoelectric composites as a driving parts. The developed transducer is evaluated the TVR(transmission voltage response) and RVS(receiving voltage sensitivity) characteristics around $4{\sim}14\;kHz$ frequency range and is compared to conventional tonpilz transducer made of solid piezoelectric ceramics as a driving parts. The resonance frequency of the developed transducer is decreased by 30% and the -3 dB bandwidth is increased by 90%, compared to conventional transducer with same dimensions. The value of TVR is decreased by 9 dB and The value of RVS is the same at resonance frequency.

A Study on Frequency Domain Fatigue Damage Prediction Models for Wide-Banded Bimodal Stress Range Spectra (광대역 이봉형 응력 범위 스펙트럼에 대한 주파수 영역 피로 손상 평가 모델에 대한 연구)

  • Park, Jun-Bum;Kang, Chan-Hoe;Kim, Kyung-Su;Choung, Joon-Mo;Yoo, Chang-Hyuk
    • Journal of the Society of Naval Architects of Korea
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    • v.48 no.4
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    • pp.299-307
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    • 2011
  • The offshore plants such as FPSO are subjected to combination loading of environmental conditions (swell, wave, wind and current). Therefore the fatigue damage is occurred in the operation time because the units encounter the environmental phenomena and the structural configurations are complicated. This paper is a research for frequency domain fatigue analysis of wide-band random loading focused on accuracy of fatigue damage estimation regarding the proposed methods. We selected ideal bi-modal spectrum. And comparison between time-domain fatigue analysis and frequency-domain fatigue analyses are conducted through the fatigue damage ratio. Fatigue damage ratios according to Vanmarcke's bandwidth parameter are founded for wide-band. Considering safety, we recommend that Jiao-Moan and Tovo-Benasciutti methods are optimal way at the fatigue design for wide-band response. But, it is important that these methods based on frequency-domain unstably change the accuracy according to the material parameter of S-N curve. This study will be background and guidance for the new frequency-domain fatigue analysis development in the future.

Design of a Wide Tuning Range DCO for Mobile-DTV Applications (Mobile-DTV 응용을 위한 광대역 DCO 설계)

  • Song, Sung-Gun;Park, Sung-Mo
    • Journal of Korea Multimedia Society
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    • v.14 no.5
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    • pp.614-621
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    • 2011
  • This paper presents design of a wide tuning range digitally controlled oscillator(DCO) for Mobile-DTV applications. DCO is the key element of the ADPLL block that generates oscillation frequencies. We proposed a binary delay chain(BDC) structure, for wide tuning range DCO, modifying conventional fixed delay chain. The proposed structure generates oscillation frequencies by delay cell combination which has a variable delay time of $2^i$ in the range of $0{\leq}i{\leq}n-1$. The BOC structure can reduce the number of delay cells because it make possible to select delay cell and resolution. We simulated the proposed DCO by Cadence's Spectre RF tool in 1.8V chartered $0.18{\mu}m$ CMOS process. The simulation results showed 77MHz~2.07GHz frequency range and 3ps resolution. The phase noise yields -101dBc/Hz@1MHz at Mobile-DTV maximum frequency 1675MHz and the power consumption is 5.87mW. The proposed DCO satisfies Mobile-DTV standards such as ATSC-M/H, DVB-H, ISDB-T, T-DMB.

Frequency Response of the electrode for Indirect-contact ECG (간접접촉 심전도 측정용 전극의 주파수 특성)

  • Lim, Yong-Gyu
    • Journal of Biomedical Engineering Research
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    • v.29 no.3
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    • pp.249-253
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    • 2008
  • The indirect-contact ECG (IDC-ECG) was introduced by a prior study for daily non-intrusive measurements. To improve the signal quality and to extend the application area of IDC-ECG, close study of the frequency characteristics of the IDC-ECG is necessary. In this study, the frequency response of the active electrode for several sample clothes was measured under conditions of actual IDC-ECG measurement with human body. Higher gain in low frequency range than expected by prior study was observed. In addition to it, wide variation in gain according to the cloth type in the low frequency range was observed. Variation in gain caused by moisture variation in the clothes was also observed. This study shows that the parallel R-C connection is proper for electrode model and the resistive factor is influenced by moisture in the clothes. This study is the first that provides the frequency response of the electrode in the actual indirect-contact ECG measurement and it is expected that the results will be helpful to improve the indirect-contact ECG method.