• Biomolecules & Therapeutics
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• v.3 no.4
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• pp.304-310
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• 1995

This study was done to investigate the effect of vitamin C on hepatic biliary and microsomal function during ischemia and reperfusion. Rats were treated with vitamin C(20, 100, 400, 1600 mg/kg) or with vehicle(saline) and then subjected to 60 min no-flow hepatic ischemia in vivo. Control animals were time-matched sham ischemic animals. After 1 or 5 hr of reperfusion, bile was collected, blood was obtained from the abdominal aorta, and liver microsomes were isolated. In vehicle-treated ischemic rats, serum ALT and AST levels peaked at 5 hr and were significantly attenuated by vitamin C 20 mg/kg and 100 mg/kg treatment. Similarly, hepatic wet weight-to-dry weight ratio was decreased in the vehicle-treated ischemic group. Vitamin C 20 mg/kg and 100 mg/kg treatment minimized the increase in this ratio. Lipid peroxidation was elevated in vehicle-treated ischemic group, but this elevation was also inhibited by vitamin C 20 mg/kg and 100 mg/kg treatment. Bile flow and cholate output, but not bilirubin output, were markedly decreased by ischemia/reperfuzion. Vitamin C 20 mg/kg and 100mg/kg treatment restored the secretion but vitamin C 1600 mg/kg reduced the cholate output. Cytochrome P-450 content was decreased by ischemia/reperfusion and restored by vitamin C 20 mg/kg and 100 mg/kg treatment to the level of sham operated group but decreased by vitamin C 1600 mg/kg. Aminopyrine N-demethylase activity was decreased and aniline p-hydroxylase activity was increased by ischemia/reperfusion. The changes in the activities of aminopyrine were prevented by vitamin C 20 mg/kg and 100 mg/kg treatment, but not by 400 mg/kg and 1600 mg/kg treatment. Our findings suggest that ischemia/reperfusion diminishes hepatic secretory functions as well as microsomal drug metabolizing systems, small doses(20, 100 mg/kg) of vitamin C significantly ameliorates and large doses(400, 1600 mg/kg) of vitamin C aggravated these ischemia/reperfusion-induced changes.

• Journal of Advanced Navigation Technology
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• v.17 no.3
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• pp.279-284
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• 2013

Among the phases of flight operations pilots feel much pressure in landing segment. There is a number of factors affecting landing safety while pilots reduce aircraft speeds and make a touchdown and stop completely. If runway length is sufficient for landing, there maybe is no problem. But it is not the case all the time. So it is necessary to confirm whether landing performance is within limits or not. Required landing distance is actual landing distance demonstrated by flight test pilot plus allowances for average airline pilots. FAR(Federal Aviation Regulations) AFM certification is based upon manual landing for dry and wet runway. Other runway conditions are not the certification basis. JAR dictates even contaminated/slippery runway is included by prescribed allowances. Automatic landing is not certification basis, so actual landing distances are provided. In this paper I would like to analyze distance allowances included in each type of runway condition. In addition there is no regulation about allowances for specific runway condition, I would suggest adequate allowances for that case.

• Proceedings of the Korea Water Resources Association Conference
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• 2011.05a
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• pp.92-92
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• 2011

수자원장기종합계획(2006)에 따르면, 우리나라는 물부족이 예상이 되고 있고, 이러한 물부족 현상은 기후변화의 영향으로 더욱 악화될 것으로 예상된다. 기후변화에 따른 물부족에 대응하기 위해서는 현행 지표수 및 지하수(Blue Water) 위주의 수자원관리와 더불어 그전에는 수자원으로 인식되지 않았던 토양수(Green Water)를 새로운 개념의 수자원으로 인식하는 것이 필요하다. 토양수는 현재 물사용량 중에서 가장 많은 비중을 차지하는 농업용수 부분에 효율적으로 활용하면, 지표수나 지하수와 같은 수자원을 대체하는 효과가 있다. 기후변화에 따른 물부족에 대응한 토양수의 효율적 활용을 위해서는, 과거 뿐아니라 미래의 지역별 시기별 토양수 공간분포특성을 분석하는 것이 선행되어야 한다. 그러므로 본 연구에서는 토양수의 분석을 통한 미래 물부족 해결에 도움이 될 새로운 수자원 관리의 기틀을 마련하기 위해 토양수 분포특성분석모델을 개발하고, 이를 활용해 과거 및 미래의 토양수의 공간분포특성을 분석한다. 토양수 분포특성분석모델은 선행 5일간의 일 강우데이터 값을 표준선행강우지표(Normalized Antecedent Precipitation Index)에 적용하여 일 단위 토양수 상태(Wet, Average, Dry condition)를 계산하는 모델이다. 과거 토양수 분석에는 인공위성 강우데이터(Tropical Rainfall Measuring Mission 3B42)를, 미래 토양수 분석을 위해서는 기상청에서 제공하는 국가표준 기후변화 시나리오(A1B)를 각각 사용하여, 과거 데이터는 27km의 격자로, 미래는 25km 격자크기로 한반도 전체의 일 단위 토양수 상태를 계산했다. 계산된 토양수 결과를 활용해 연 월별 그리고 토양수를 쓸 수 있는 시기, 즉 식물이 자라는 시기(4-9월)의 특성을 분석했다. 이를 통해 향후 기후변화에 따른 물부족 대응 토양수 수자원 활용방안에 도움이 될 것으로 예상된다.

• Korean Journal of Remote Sensing
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• v.11 no.3
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• pp.117-127
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• 1995

In this paper several methods for retriving appropriate values of effective soil moisture contents from natural soil surfaces are introduced and compared each other. The soil medium has usually a nonuniform moisture profile; i.e., relatively dry at the top layer and relatively wet at the bottom layer. The effective soil moisture represents the quantitative value of soil moisture of the inhomogeneous soil medium in an average sense. A simple method is an arithmetic averaging of soil moisture values obtained from several layers of a soil surface. Otherwise, the penetration depths can be computed from a homogeneous and an inhomogeneous soil surfaces and compared in order to obtain the effective soil mosture. The other method is to obtain the effective soil moisture by comparing the reflectivities from both of a homogeneous and an inhomogeneous surfaces. Those methods are compared and the reflectivity technique is examined in more detail since the rader scattering is dominated by the reflectivity instead of the penetration.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.29 no.3
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• pp.310-321
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• 2019

Objectives: The purpose of this study was to investigate types and characteristics of chemical substances used in LCD(Liquid crystal display) panel manufacturing process. Methods: The LCD panel manufacturing process is divided into the fabrication(fab) process and module process. The use of chemical substances by process was investigated at four fab processes and two module processes at two domestic TFT-LCD(Thin film transistor-Liquid crystal display) panel manufacturing sites. Results: LCD panels are manufactured through various unit processes such as sputtering, chemical vapor deposition(CVD), etching, and photolithography, and a range of chemicals are used in each process. Metal target materials including copper, aluminum, and indium tin oxide are used in the sputtering process, and gaseous materials such as phosphine, silane, and chlorine are used in CVD and dry etching processes. Inorganic acids such as hydrofluoric acid, nitric acid and sulfuric acid are used in wet etching process, and photoresist and developer are used in photolithography process. Chemical substances for the alignment of liquid crystal, such as polyimides, liquid crystals, and sealants are used in a liquid crystal process. Adhesives and hardeners for adhesion of driver IC and printed circuit board(PCB) to the LCD panel are used in the module process. Conclusions: LCD panels are produced through dozens of unit processes using various types of chemical substances in clean room facilities. Hazardous substances such as organic solvents, reactive gases, irritants, and toxic substances are used in the manufacturing processes, but periodic workplace monitoring applies only to certain chemical substances by law. Therefore, efforts should be made to minimize worker exposure to chemical substances used in LCD panel manufacturing process.

• Proceedings of the Korea Water Resources Association Conference
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• 2018.05a
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• pp.158-158
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• 2018

Drought is a recurrent natural hazard in Bangladesh. It has significant impacts on agriculture, environment, and society. Well-timed information on the onset, extent, intensity, duration, and impacts of drought can mitigate the potential drought-related losses. Thus, drought characteristics need to be explained in terms of frequency, severity, and duration. This paper aims to characterize the spatial and temporal pattern of meteorological drought using EDI and illustrated drought severity over Bangladesh. Twenty-seven (27) station-based daily rainfall data for the study period of 1981-2015 were used to calculate the EDI values over Bangladesh. The evaluation of EDI is conducted for 4 sub-regions over the country to confirm the historical drought record-developed at the regional scale. The finding shows that on average, the frequency of severe to extreme drought is approximately 0.7 events per year. As a result of the regional analysis, most of the recorded historical drought events were successfully detected during the study period. Additionally, the seasonal analysis showed that the extreme droughts were frequently hit in northwestern, middle portion of the eastern and small portion of central parts of Bangladesh during the Kharif(wet) and Rabi(dry) seasons. The severe drought was affected recurrently in the central and northern regions of the country during all cropping seasons. The study also points out that the northern, south-western and central regions in Bangladesh are comparatively vulnerable to both extreme and severe drought event. The study showed that EDI would be a useful tool to identify the drought-prone area and time and potentially applicable to the climate change-induced drought evolution monitoring at regional to the national level in Bangladesh. The outcome of the present study can be used in taking anticipatory strategies to mitigate the drought damages on agricultural production as well as human sufferings in drought-prone areas of Bangladesh.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.603-603
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• 2015

모든 외재적 형식의 가뭄을 모니터링하고 예측 및 평가하기 위해서는 가뭄지수가 필수적 요소로써 이용된다. 일반적으로 가뭄지수는 단일지수(single index), 다중지수(multiple index), 복합지수(composite index)로 분류되며 대부분 강수량, 유출량, 토양 수분량 등과 같은 하나의 변수만을 사용하는 단일지수이다. 가뭄지수는 가뭄평가에 있어서 각각의 장단점이 있다. 하나의 변수를 사용하는 가뭄지수는 계산이 간편하지만 가뭄의 물리적 특성을 정확하게 반영할 수 없기 때문에 신뢰할 수 있는 가뭄평가에 충분하지 않다. CDI(Composite Drought Index)는 PDSI(Palmer Drought Index), ADI(Aggregate Drought Index), SWSI(Surface Water Supply Index)와 같은 다중지수의 개념을 착안하여 고안되었으며, 모든 가뭄 형태(농업적 수문학적 기상학적)와 관련된 강우량, 유출량, 정규식생지수(NDVI)를 변수로써 사용하였다. NDVI는 MODIS(Moderate resolution imaging spectroradiometer)에서 제공하는 16일 간격의 위성자료를 이용하여 계산되었고 이와 시간 스케일을 맞추기 위해 나머지 두 변수 또한 16일 시계열을 사용하였다. CDI는 (1)각 변수들의 시계열을 행렬로 나타내고 (2)이것을 정규화하여 무차원 행렬로 변환한 후 (3)연구 지역의 최고습윤상태(most wet condition) 및 최고건조상태(most dry condition)의 차이값을 기반으로 하여 산정된다. 본 연구에서는 상대적으로 다른 유역에 비해 장기적이고 연속적인 자료를 확보할 수 있으며 농경지와 산림지역 비율이 높은 낙동강 유역을 대상유역으로 설정하였으며, 2001-2013년 기간의 자료를 이용하였다. 그 결과 연구 기간 중 실제 발생했던 가뭄을 반영하는 것을 확인하였다. 또한 CDI는 다양한 변수의 활용으로 가뭄의 물리적 특성의 반영이 가능하며 연구 지역의 기상 조건에 직접적으로 관련된 결과를 나타낸다. 자료의 가용성에 따라 적용범위가 제한적일 수 있으나 입력값으로 사용된 변수와 시계열을 편의와 효율에 따라 유연하게 적용할 수 있다. 따라서 CDI는 농업적, 수문학적, 기상학적 가뭄의 모든 관점을 통합하는 실용적 가뭄지수로써 사용될 수 있는 가능성을 포함하고 있다.

• Journal of Climate Change Research
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• v.7 no.3
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• pp.249-256
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• 2016

Porous $Al_2O_3$ hollow fiber membranes were successfully prepared by dry-wet spinning/sintering method. The SEM image shows that the $Al_2O_3$ hollow fiber membrane consists mostly of sponge pore structure. The contact angle and the breakthrough pressure were $126^{\circ}$ and 1.91 bar, respectively. This results indicate that the $Al_2O_3$ hollow fiber membranes were successfully modified to hydrophobic surface. The hydrophobic modified $Al_2O_3$ hollow fiber membranes were assembled into a membrane contactor system to separate $CO_2$ from a model gas mixture of the flue gas at elevated gas velocity. The $CO_2$ absorption flux was enhanced when the gas velocity increased from $1{\times}10^{-3}$ to $6{\times}10^{-3}$ m/s. Whereas the $CO_2$ absorption flux was decreased with the number of hollow fiber membrane of a module because of the concentration polarization. Furthermore, we developed an lab-scale $Al_2O_3$ hollow fiber membrane contactor modules and their system (i.e., $CO_2$ absorption using the $Al_2O_3$ membrane and monoethanolamine (MEA)) that could dispose of over $0.02Nm^3/h$ mixture gas (15% $CO_2$) with the removal efficiency higher than 95%. The results can be useful in a field of the membrane contactor for $CO_2$ separation, helping to design and extend a equipment.

• The Korean journal of internal medicine
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• v.33 no.6
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• pp.1137-1142
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• 2018

Background/Aims: This study tested the hypothesis that prolonged low-dose cyclophosphamide (CTX) treatment after pulse therapy attenuate paraquat (PQ)-induced lung injury in rats. Methods: PQ (25 mg/kg) was administered intraperitoneally to induce PQ-intoxicated rat model. The rats were randomly divided into four groups: control group (1 mL/day saline solution for 14 days), PQ group (1 mL/day saline solution for 14 days after PQ exposure), pulse group (15 mg/kg/day CTX in 1 mL of saline solution for 2 days and subsequent 1 mL/day saline solution for 12 days), and prolonged low-dose group (15 mg/kg/day CTX in 1 mL of saline solution for 2 days and subsequent 1.5 mg/kg/day CTX in 1 mL of saline solution for 12 days). A 14-day follow-up was conducted to determine the survival rat, and lung hydroxyproline (HYP), wet-to-dry weight ratios (W/Dc) and histopathological changes were evaluated. Results: Results showed similar survival rate (55% vs. 50%, p > 0.05) between prolonged low-dose and pulse groups. Lung W/Dc ($4.94{\pm}0.38$ vs. $5.47{\pm}0.28$, p < 0.01), HYP ($3.34{\pm}0.29{\mu}g/mg$ vs. $3.65{\pm}0.19{\mu}g/mg$, p < 0.001), and fibrosis score ($2.69{\pm}0.84$ vs. $3.13{\pm}0.63$, p < 0.05) were lower in prolonged low-dose group than those in the pulse group. Conclusions: These findings suggested prolonged low-dose CTX treatment after pulse therapy could attenuate PQ-induced lung injury in rats.

• Resources Recycling
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• v.27 no.6
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• pp.11-22
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• 2018

Magnetic separators has been used in the mining and the recycling fields in general, and is still applied in wide variety of fields. It is classified into the equipments for separating coarse ferrous scrap from non-ferrous materials and the equipments for concentrating fine ferromagnetic particles below 3mm. Magnetic separation equipments for concentrating fine materials also falls into two categories of low intensity and high intensity magnetic separators. The former is used for ferromagnetic materials but also paramagnetic materials of high magnetic susceptibility, and the latter for paramagnetic materials of lower magnetic susceptibility. Both low and high intensity magnetic separators could be utilized either dry and wet. Recently, the High gradient magnetic separators(HGMS) used in the range of less than 0.7 tesla has been gradually replaced by the magnetic separator made of rare earth permanent magnets commercialized in the 1980s. In addition, the expansion of nanotechnology in terms of synthetic magnetic materials in the environmental and biological fields is expected to contribute positively to the development of magnetic separation technology.