• 한국노년학
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• v.28 no.4
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• pp.953-968
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• 2008

This research was performed to recognize anxiety level of older people, to find out anxiety level after or before regular exercises, and to find out how much anxiety level could be lowered by the sports activities. This research selected a population among the students who enrolled at sport activity classes (e, g., physical exercises, gate ball, volume dance) at L, S, J, Y (a), Y (b), D older people college located in Seoul and Gyoenggi area. 200 of the population were chosen as candidates by convenience sampling, nonprobability sampling. Considering the age of the candidates, total 200 cases were collected by using two methods (survey and interview) simultaneously. The data assessment was made by SPSS 12.0 Version. Error tolerance in statistics is .05. The data was analyzed by using frequency analysis, paired t-test and independent t-test. After analyzing anxiety awareness level after and before regular exercises, anxiety of older people are classified by four factors. First, anxiety for loss is 3.756 (M=3.756) before exercises, while 1.942 (M=1.942) after exercises. Second, fear for aging is 3.443 before exercises and 2.243 after exercises. Third, anxiety for physical appearance is 3.253 before exercises and 2.310 after exercises. Finally, anxiety caused by psychological insecurity is 3.060 before exercises, while 1.666 after exercises. Error of tolerance for all factors falls within .001. Anxiety score after exercises is lower than that of before exercises for every factor as well. As a result, regular physical exercises appeared to reduce anxiety level of older people.

• Journal of Life Science
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• v.28 no.12
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• pp.1455-1460
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• 2018

Due to a rapidly expanding aging population, the incidence of degenerative bone disease has increased, and efforts to handle the issue using regenerative medicine have become more important. In order to control various bone diseases such as osteoarthritis and osteoporosis, regenerative medicine utilizing adult stem cells has been extensively studied. And it is now clear that the mitochondrial energy metabolism, oxidative phosphorylation, is important for the process of stem cell differentiation. Interestingly, a recent study reported that salicylate promotes mitochondrial biogenesis by regulating the expression of $PGC-1{\alpha}$ in murine cells. However, the possible effects of salicylate on osteogenic differentiation through increased mitochondrial biogenesis in stem cells remain unknown. Thus, here we investigated whether salicylate could influence osteogenic differentiation and mitochondrial biogenesis of periosteum-derived mesenchymal stem cells (POMSCs). We found that salicylate treatments of POMSCs undergoing osteogenic differentiation increased the activity of alkaline phosphatase, a well-known early marker of bone cell differentiation. In addition, we observed that mitochondrial mass was increased by salicylate treatments in POMSCs. Together, these results indicate that salicylate can enhance osteogenic differentiation and mitochondrial biogenesis in POMSCs. Therefore, the findings in this study suggest that small molecules augmenting mitochondrial function such as salicylate can be a novel modulator for osteogenic differentiation and regenerative medicine.

• Industry Promotion Research
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• v.6 no.3
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• pp.25-35
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• 2021

Middle-aged women experience diverse psychological and physical stresses and tensions through the menopause, aging, and taking up too many social roles, which often leads to sleep disorder. But there are not many scientific researches on the issue. Therefore, the research of efficacy of singing bowl that helps relax middle-aged women who have sleep disorder is needed to improve their health. This study was conducted with Giorgi's phenomenological method with 4 middle-aged women with sleep disorder, whose Pittsburgh sleeping quality scale marked over 5 points, who took part in singing bowl experience for 40 minutes and did the interview. The study resulted in following conclusions that through participants' singing bowl experience, 518 constructive meanings, 15 meaning units, 7 sub components, and 2 group subjects were drawn up. Firstly, when participants took part in the singing bowl experience, they underwent physical, mental, imagery experiences which are physical pain and muscle relaxation, mental relaxation, and positive mindset and imaginary images and colors. Secondly, physical changes that the participants felt after singing bowl experience was increased physical relaxation, improved physical symptoms and more physical activities, and psychologically participants also felt reduced anxiety, increased happiness and positive mentality. And behavioral changes are relaxed movements, increased activities, and improved sleep is huge benefit through changes of sleep pattern. In this study, singing bowl is confirmed to be effective both physically and psychologically on relaxing the middle-aged women's tensions that are caused by sleep disorders and singing bowl experience is meaningful in that the middle-aged women as well as modern people with the sleep disorders can be helped to have better lives.

• Journal of Digital Convergence
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• v.19 no.1
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• pp.59-66
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• 2021

As the demand for elderly care service has been on rise due to the increasing of the aging population, the role of visiting caregivers becomes increasingly important. In this context, this study aims to examine whether there are moderating effects of social support and self-efficacy on the relationship between resilience of visiting caregivers and their burnouts. The hierarchical regression analysis was used for statistical analysis. The findings from the study are as follow. First, resilience has a negative effect on burnout. As the resilience increases, the burnout decreases. Second, social support has moderating effects on the relationship between a resilience sub-variable(positivity) and burnout. Third, self-efficacy has a moderating effect on the relationship between a resilience sub-variable(self-regulation) and burnout. The findings of the study suggest that nursing facilities pay attention to psychological characteristics of visiting caregivers as well as their job characteristics in designing burnout prevention programs for them.

• 한국사회정책
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• v.24 no.2
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• pp.61-86
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• 2017

Along with the well-established evidence on the negative effect of social isolation on physical and mental health, increasing attention has been paid to multi-dimensional nature of social isolation. One line of study on social isolation has discussed different pathways between objective and subjective social isolation and health. Another stream of the research focused on the possibly non-linear association between social isolation and health by age cohort groups. Drawing from the two lines of research, this study aimed at empirically examine to what extent objective and subjective social isolation are associated with physical and mental health independently and how the associations vary by three age cohorts(i.e. the middle-aged, the young old, the old-old). Data came from the first wave of Korean Social Life, Health and Aging Project (KSHAP) (N= 814). Findings showed 1) objective subjective isolation were significantly related with worse physical and mental health, interestingly, subjective social isolation was associated with mental health only, 2) pattern of association between social isolation and physical health varied by age cohorts. Specifically, compared to the middle-aged, the young old with higher objective social isolation exhibited lower level of physical health, while the old-old with higher subjective social isolation were likely to experience lower physical health. Based on the findings, we discussed implications and suggestions for future research and relevant policy/program development for ameliorating objective and subjective social isolation.

• Journal of dental hygiene science
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• v.20 no.4
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• pp.221-229
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• 2020

Background: The purpose of this study was to investigate the anti-oral microbial activity and anti-inflammatory effects of rosmarinic acid (RA) in lipopolysaccharide (LPS)-stimulated MC3T3-E1 osteoblastic cells on a titanium (Ti) surface during osseointegration, and to confirm the possibility of using RA as a safe natural substance for the control of peri-implantitis (PI) in Ti-based dental implants. Methods: A disk diffusion test was conducted to confirm the antimicrobial activity of RA against oral microorganisms. In order to confirm the anti-inflammatory effects of RA, inflammatory conditions were induced with 100 ng/ml of LPS in MC3T3-E1 osteoblastic cells on the Ti surface treated with or without 14 ㎍/ml of RA. The production of nitric oxide (NO) and prostaglandin E2 (PGE2) in LPS-stimulated MC3T3-E1 osteoblastic cells on the Ti surface was confirmed using an NO assay kit and PGE2 enzyme-linked immunosorbent assay kit. Reverse transcription polymerase chain reaction and western blot analysis were performed to confirm the expression of interleukin (IL)-1β and tumor necrosis factor (TNF)-α in total RNA and protein. Results: RA showed weak antimicrobial effects against Streptococcus mutans and Escherichia coli, but no antimicrobial activity against the bacteria Aggregatibacter actinomycetemcomitans and the fungus Candida albicans. RA reduced the production of pro-inflammatory mediators, NO and PGE2, and proinflammatory cytokines, TNF-α and IL-1β, in LPS-stimulated MC3T3-E1 osteoblastic cells on the Ti surface at the protein and mRNA levels. Conclusion: RA not only has anti-oral microbial activity, but also anti-inflammatory effects in LPS-stimulated MC3T3-E1 osteoblasts on the Ti surface, therefore, it can be used as a safe functional substance derived from plants for the prevention and control of PI for successful Ti-based implants.

• Journal of dental hygiene science
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• v.21 no.2
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• pp.96-103
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• 2021

Background: We aimed to investigate the effect of Citrous limon extract (CLE) on oxidative stress-induced cytotoxicity and nitric oxide (NO) generation and the tooth bleaching effect of CLE as a substitute for hydrogen peroxide (H₂O₂) and determine the feasibility and application of CLE as a safe and effective natural tooth bleaching agent. Methods: The protective effect of CLE on H₂O₂-induced cytotoxicity in Raw264.7 macrophages was investigated by the MTT assay. The inhibitory effect of CLE on the generation of H₂O₂-induced NO was confirmed by the NO assay, and the changes in inducible nitric oxide synthase (iNOS) protein expression were confirmed by western blotting. Stained bovine teeth were treated with/without 15% and/or 35% CLE and H₂O₂, 15% sodium bicarbonate (NaHCO₃) for 3 hours, and were irradiated with/without bleaching light (BL) for 15 minutes. The color change of the treated bovine tooth surface was measured using a colorimeter. Results: The viability of Raw264.7 cells treated with each concentration of CLE and 500 μM H₂O₂ significantly increased as CLE increased, and NO generation and iNOS protein expression were significantly reduced in cells treated with 300 ㎍ CLE+/500 μM H₂O₂+ and 300 ㎍ CLE+/500 μM H₂O₂+/150 ㎍ NaHCO₃+. The bleaching effect of 35% CLE+ was higher than that of 15% CLE+ and 15% NaHCO₃+, and the effect was similar to that of 15% H₂O₂+. The 35% CLE+/15% NaHCO₃+ showed the greatest bleaching effect and was higher than that of the groups irradiated with the BL. The greatest bleaching effect was observed with 35% CLE+/15% NaHCO₃+, followed by 35% H₂O₂+/BL+. Conclusion: CLE inhibited oxidative stress-induced cytotoxicity and NO generation in Raw264.7 cells and, could replace H₂O₂, which causes side effects and risks in teeth breaching treatment. It showed greatest teeth bleaching effect when combined with NaHCO₃. CLE is an effective and safe natural tooth bleaching substitute.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.47 no.1
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• pp.65-73
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• 2021

It is very important to control the inflammation of the skin because it can develop into diseases such as atopy as well as scarring and aging. In this work, we recently identified the in vitro synthesis of specialized pro-resolving mediators (SPMs) known to control inflammation in the human body and the applicability of cosmetics. Using recombinant protein of lipoxygenase from Glycine max, we succeeded to prepare mixtures of mono- or di-hydroxy DHA named as S-SPMs and used them for in vitro efficacy test. To investigate anti-inflammatory effect of S-SPMs, mRNA level of TNF-α and IL-6 were analyzed. Under UVB exposed condition, expression of both were decreased by S-SPMs treatment. And we observed reduced production of nitric oxide (NO) by S-SPMs application under the condition with diesel particulate matter (DPM). At the same experimental condition, malondialdehyde (MDA) production was decreased by S-SPMs, indicating the inhibitory effect of S-SPMs in lipid peroxidation. In addition, S-SPMs treatment resulted in reduction of matrix metalloproteinases-1 (MMP-1) expression and elevation of procollagen type I synthesis. Together with this, mRNA level of filaggrin and loricrin were increased by S-SPMs, indicating enhancement of skin barrier function. These results demonstrate that S-SPMs is a good candidate to develop as a cosmetic ingredient for anti-inflammation, anti-wrinkle, and improvement of skin barrier function.

• Korean Journal of Remote Sensing
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• v.36 no.6_2
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• pp.1493-1507
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• 2020

The LEOP Cal/Val (Launch and Early Operation Phase Calibration/Validation) was carried out during 6 months after KOMPSAT-3A (KOMPSAT-3A Korea Multi-Purpose Satellite-3A) was launched in March 2015. After LEOP Cal/Val was successfully completed, high resolution KOMPSAT-3A has been successfully distributing to users over the past 8 years. The sub-meter high-resolution satellite image data obtained from KOMPSAT-3A is used as basic data for qualitative and quantitative information extraction in various fields such as mapping, GIS (Geographic Information System), and national land management, etc. The KARI (Korea Aerospace Research Institute) periodically checks and manages the quality of KOMPSAT-3A's product and the characteristics of satellite hardware to ensure the accuracy and reliability of information extracted from satellite data of KOMPSAT-3A. To minimize the deterioration of image quality due to aging of satellite hardware, payload and attitude sensors of KOMPSAT-3A, continuous improvement of image quality has been carried out. In this paper, the Cal/Val work-flow defined in the KOMPSAT-3A development phase was illustrated for the period of before and after the launch. The MTF, SNR, and location accuracy are the key parameters to estimate image quality and the methods of the measurements of each parameter are also described in this work. On the basis of defined quality parameters, the performance was evaluated and measured during the period of after LEOP Cal/Val. The current status and characteristics of MTF, SNR, and location accuracy of KOMPSAT-3A from 2016 to May 2020 were described as well.

• Journal of Korean Academy of Dental Administration
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• v.8 no.1
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• pp.15-23
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• 2020

The aim of this study is to identify future-oriented tasks for Korean dental hygienists based on a literature review. A literature search is performed using 14 keywords related to tasks carried out by dental hygienists, and included articles published from 2000 to 2019 in the databases KISS, RISS, DBpia, NDSL, Papersearch, Pubmed, and Google Scholar. Six reviewers assessed the titles and abstracts of articles, and an article was selected if the study was considered to cover future-oriented tasks for Korean dental hygienists. Based on the results six local studies and two foreign studies were used for literature review and data extraction. In total, 38 tasks were classified as future-oriented tasks of dental hygienists according to the following criteria: 1) tasks that were specifically referred to as future-oriented tasks, and 2) tasks that could be classified as future-oriented tasks although no specific reference was made. Of these, the most frequently mentioned tasks were measuring periodontal pocket depth, dental hygiene assessment, providing dietary advice, infiltration anesthesia, and root planing. These were extracted from five of the eight studies, including both local and foreign studies. Dental hygiene planning, emergency, emergency management, and smoking cessation were the next most common tasks based on four studies. Even though some of these future-oriented tasks for Korean dental hygienists are included in the dentistry curriculum, and are currently performed as clinical practice for dental hygienists. Nonetheless, the reference to the legal scope is unclear. It is necessary to reconsider the scope of tasks of dental hygienists to reflect changes in domestic and foreign dental care delivery, thereby contributing to the oral health promotion of the public, where safety is guaranteed under legal protection.