• Biomolecules & Therapeutics
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• 제15권2호
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• pp.83-88
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• 2007

The roots of Liriope platyphylla (Liliaceae) are widely used in traditional Chinese medicine. In the present study, we investigated the effects of ethanol (70%) extract of the roots of Liriope platyphylla (ELP70) on learning and memory using behavioral and immunohistochemical methods in mice. Control animals were treated with vehicle (10% Tween 80). With sub-chronic treatments of ELP70 (p.o.) for 14 days, the latency time was significantly increased compared with that of the vehicle-treated control group (50, 100 and 200 mg/kg; P<0.05). Moreover, immunopositive cells for brain derived neurotrophic factor (BDNF) were significantly increased in the hippocapmpal dentate gyrus and CA1 regions after ELP70 treatments for 14 days (50, 100 and 200 mg/kg; P < 0.05). In addition, those cells for nerve growth factor (NGF) were also increased in the hippocapmpal dentate gyrus region (50, 100 and 200 mg/kg; P<0.05). These results suggest that the sub-chronic administration of ELP70 improves learning and memory, and that their beneficial effects are mediated, in part, by the enhancement of BDNF or NGF expression.

• 재활복지공학회논문지
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• 제8권3호
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• pp.151-160
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• 2014

본 연구에서는 기존의 시/청각 방식의 운전정보 전달체계의 한계를 극복하고 더불어 교통약자들의 운전수행에 도움이 되는 자동차용 햅틱 시트 기술을 개발하고자 하였다. 이를 위해 동전형 모터 30개를 사용한 진동자극용 시트커버형 시제품과 모터드라이버모듈을 제작하였고 65세 이상의 고령 피험자들을 대상으로 실시한 가상운전상황에서의 시트진동자극에 대한 실험에서는 피험자들의 전체 진동인지 점수 평균은 3.5/4점으로 87.5%의 인지율을 보여주었다. 또한 모든 피험자가 4번의 과속경고신호를 모두 인지하는 결과를 보여주었다. Trail Making Test 점수에 따른 그룹별 진동인지점수에 대한 통계분석 결과 유의한 차이가 발견되지 않았고 시각기능과 인지기능이 저하된 고령자라도 진동을 인지하는 촉각기능은 동등한 능력을 보여주는 결과를 얻었으며 이 결과는 고령운전자에 대한 차량 내에서의 시트를 통한 진동자극의 운전정보 유용성을 보여주는 것으로 사료된다.

• 보건교육건강증진학회지
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• 제23권3호
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• pp.65-83
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• 2006

Objectives: This is one of the first efforts to describe incidence of alcohol-related problems and to identify environmental correlates associated with them among colleges. Methods: Date were collected by a sample of 105 college administrators who are in charge of student affairs in colleges nationwide through self-administrated questionnaire. Both logistic and linear multiple regression analyses were employed to identify the correlates associated with alcohol-related problems. Results: Most of colleges(76.6%) under study reported to have at least one alcohol-related problem in previous years. Interpersonal violence was alcohol-related problem taken placed most frequently, followed by making noise episode, having property damaged and motor vehicle accidents. Logistic regression analysis identified factors associated with incidents of alcohol related problems. They included being private colleges, numbers of prevention activities, product promotion and marketing by alcohol industry and alcohol accessibility to drinking context. Multiple regression analyses showed that correlates associated with numbers of alcohol-related problems included being a private college, being located in rural area, having drinking density, product promotion and availability of alternative activities to drinking. Conclusions: Environmental correlates were associated with incidence of alcohol related problems in colleges nationwide. Policy implications were discussed.

• 한국음향학회지
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• 제19권6호
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• pp.3-9
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• 2000

The Bell King Songdok the Great tolls magnificient sound that would be a great vehicle which brings all beings to the Sutras. Since 693, there was a magic flute, MANPASIKJUK, which was in existence in Shilla Dynasty that could lull all the evil-wawes, such an plaques, storms, Droughts, Famines and even Enemies. Thus, a sound tube, MANPASIKJUK, was erected in the crown of the Bell Songdok the Great so as to be effective to emit the nominal frequency tone whenever the Bell tolls for the national prosperity and welfare the People. Therefore, the Bell makers tried to fine the transmissibility condition through the sound tubr, several times during 34 years, However, it seems to be unfinished. Ever since, all of the korean Brahman Bell have the sound tubes of MANPASIKJUK, but none is performed their own functions. Here, one of the way to let the function of the sound tube of MANPASIKJUK out in the Bell Songdok the Great is proposed. There are two steps: the 1st is to elongate 18cm to the present length 77cm to fulfill the transmissibility condition for the nominal frequency of sound is emitted through the corrected sound tybe. 2nd step is to rise to 95% of the emission of the tone of nominal frequency, so that an exponential hem with the flare constant 2.8m-1, length 2.259m and the radius of the mouth 1.772m is to be extended to the corrected sound tube.

• 한국축산식품학회지
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• 제24권4호
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• pp.424-432
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• 2004

The handling and transport of broiler birds from farm to the processing factory is known to cause injury and dead. The preslaughter period can be compromised through thermal stress, emotional stress, starvation, dehydration, metabolic exhaustion, trauma to the skin and bone fraction resulting in bruising and dead. This paper focuses on the control points of individual post Harvest stages by reference to recent literature. In catching, the injuries and deads are caused from fracture of bone, skin damage and hipbone dislocation. It can be improved by training the catchers. The primary factor of dead during transportation is from thermal stress. It is related to stocking density, type of crate and vehicle, ventilation and transportation time. Of the factors, the ventilation is very important. The holding place should be built with consideration of protection from the hostile external environment. There were not much progresses in this area, however, many researches are conducting to focus on animal welfare in European Union. Recently, it is rapidly changed in marketing custom from whole carcass to portion cut in Korea. This means the increase of economic loss due to the mishandling at post harvest. The systematic approach is demanded for this area.

• 전자공학회논문지CI
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• 제48권2호
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• pp.106-116
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• 2011

USN(Ubiquitous Sensor Network) 환경은 언제, 어디서나 정보를 이용할 수 있게 한다. 이러한 환경의 기반이 되는 기술은 타겟의 정확한 위치설정을 전제로 한다. 특히 ITS(Intelligent Transportation Systems)는 USN 기술을 적용함으로써 쉽게 구축 될 수 있다. 위치측정은 Range-based 방식과 Range-free 방식으로 나눌 수 있다. Range-based 방식은 전파의 불규칙하고 추가 장비가 필요로 센서네트워크기반 위치측정에 적합하지 않은 것으로 알려져 있다. 반면에 Range-free 방식은 능동적인 통신을 수단으로 위치를 측정하므로 자원제약적인 센서네트워크에서는 적합한 것으로 알려져 있다. 그러나 Range-free 방식은 일반적으로 정확성이 부족하며, 특히 밀집도가 낮은 환경에서는 정확성이 매우 낮다. 따라서 이 두 기법은 장단점을 가지고 있다. 그러므로 두 기법을 혼합하여 위치추적의 정확성을 개선할 수 있는 새로운 기법이 요구된다. 본 논문은 Range-free 방식을 개선할 수 있도록 추가 장비가 요구되지 않은 RSSI(Received Signal Strength Indication) 신호 값을 분류하고 주변노드의 위치와 통신범위 및 세기정보를 최대한 활용하여 이동차량을 보다 정확하게 추적할 수 있는 Range-hybrid 기반의 위치추적기법을 제시한다. 추가적으로 예측기법을 활용하여 위치추적의 정확성을 획기적으로 개선할 수 있는 방안을 제시한다. 그리고 시뮬레이션 결과, 제안된 기법이 기존 위치추적 알고리즘 보다 교통 환경에서 위치추적의 정확도가 우수함을 증명하였다.

• 재활복지공학회논문지
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• 제5권1호
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• pp.17-25
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• 2011

본 논문은 전동 보행보조기의 편의성 향상을 위한 최적의 제어 이득을 찾고 제어 알고리즘을 설계하였다. 최근 노인의 인구가 의료 기술의 발달로 급속히 증가되고 있으며, 다양한 이동형 보행보조기구는 삶의 질을 개선하기 위해 개발되고 있다. 이러한 이동형 제품 중 수동형 보행보조기는 노인의 보행의 힘을 도와주는 전동모터를 가지고 있지 않아 노인들이 충분한 근력이 없기 때문에 경사로 및 문의 문턱 등 고르지 않는 지형에서 이동하는데 제안사항이 있다. 이러한 상황을 극복하기 위해 전동타입의 보행보조기를 개발하였다. 전동형 보행보조기는 수동형과 다르게 사용자가 조작을 해야 모터가 구동되는 구조이다. 이러한 구조는 사용자가 조작을 잘못 하였을 경우 상당한 불편함을 사용자에게 준다. 이러한 전동형 보행보조기를 수동형 보행보조기와 비교하여 조작의 편의성을 판단하고 기준을 만들어 사용자의 편의성에 대하여 제어 값을 변경하면서 사용자 편의성을 개선하였다. 본 논문에서는 보행의지를 인식하고 편의성의 성능을 측정할 수 있는 방법인 햅틱 센서를 소개하며 편의를 개선하는 제어 알고리즘을 제안한다. 또한 편의성의 평가는 COV(Center of Vehicle)와 사용자의 COP(Center of Position)과의 차이의 변화를 통해 상대적인 편의성을 평가하였다. 전동 타입 보행보조기와 새로운 측정방법을 도입하여 모든 과정을 실험을 통하여 확인 하였다.

• 한국융합학회논문지
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• 제8권2호
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• pp.253-258
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• 2017

현대사회가 산업화, 도시화, 정보화로 풍요로운 삶과 동시에 기계화와 경쟁화로 인간소외와 스트레스로 인하여 자아상실이 발생하여 부적응 현상들이 많이 나타나고 있다. 발생한 부적응을 적응으로 변화하기 위하여 진실한 자신과 참나와의 만남에 노력을 기울여야 한다. 일상생활에서 진실한 자신 참나와의 만남의 도구로서 차는 좋은 역할을 한다. 따라서 본 연구에서는 차를 진실한 나를 느끼고 이해하기 위하여 다례를 통해서 자신을 존중하고 사랑하는 참나를 만나는 참나다례를 구성하고 대중화를 위하여 표준 웹 프로토콜 기술을 활용한다. 참나다례는 준비단계를 거쳐, 가장 기본적인 다도구를 사용한다. 참나다례는 차와 나를 소통하기 위하여 다도구와 나를 정화하는 단계, 나를 이해하며 차 우리기 단계, 나를 존중하며 차 마시기 단계, 참나를 만나는 단계로 구성되어 있다. 본 논문에서는 참나다례를 구성하고, 표준 웹 프로토콜 기술을 활용하여 참나다례의 대중화를 제안하였다. 표준 웹 프로토콜 기술을 활용하면 이용자의 접근성이 증대되므로 언제 어디서나 참나다례를 접할 수 있다.

• International Journal of Industrial Entomology and Biomaterials
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• 제33권2호
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• pp.85-91
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• 2016

Exosomes are homogenous vesicles of 40-100 nm diameter produced endogenously. Exosomes are generated by inward budding into multi-vesicular bodies (MVB) and then released to extracellular space. Exosomes contain various nucleic acid and protein cargoes from their cells of origin and this endosomal cellular molecules are used for intracellular communication and for both promotion and suppression of immune responses. Recently, they are also considered as delivery vehicle for therapeutic proteins due to their characteristics of stability in body fluids and ability for target uptake. Also, they show less immune reactivity because the isolated exosome harboring therapeutic proteins can be from the same host. White-spotted flower chafer, Protaetia brevitarsis is one of the major insect commercially reared in Korea. There are bacterial and fungal pathogens causing diseases in the beetle, and these diseases incur economic loss to the larva-rearing farms. Due to their endosomal cargoes, exosomes are good candidates in use of disease diagnosis. In this study, we isolated insect exosome from the hemolymph of P. brevitarsis, and verified it by analysis of the exosome-specific surface proteins and RNA.

• 대한지역사회영양학회지
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• 제11권2호
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• pp.240-252
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• 2006

A survey was implemented to suggest basic data for assuring the safety of cooked foods in foodbank operations. A questionnaire consisted of total 48 items including general characteristics, basic inputs and perceived importance/performance of sanitary management. One hundred twenty-eight responses among the 267 nationwide foodbanks were used for the statistical analysis. About forty-one percent of foodbanks was operated a period of 1-3 years and 43.0% of them were managed by social welfare organizations. The number of staff was only 0.5 person per operation with the whole responsibility and 1.0 with additional work, and thus most of the work was managed by volunteers. Job satisfaction was shown to be moderate and was affected by specialty and salary mostly. The facilities and equipment in foodbanks were not enough to operate and freezers/refrigerators were the top priority to supplement. Most of the respondents attended a nationwide level sanitary education program (79.7%); but complained not enough frequency of education (90%). The sanitary status of the donated foods was considered as satisfactory but some safety practices had to be improved, including personnel expenses and operating costs in the district level, a sanitary awareness of the donors and a general management of the facilities arid equipment. An assessment on sanitary management resulted in an overall average of 4.45 out of 5 points in importance and 3.85 in performance showing the high level of sanitation perception in foodbank managers. From the IPA analysis, the fields found to be improved were sanitation management during cooking and temperature control as well as cleanliness and sanitation of both transport vehicle and refrigerator/freezer. To secure the food safety in foodbanks, consequently, personnel support, supplement of facilities and equipment, intense sanitation education and development of sanitation management program is needed.