• Design & Manufacturing
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• v.17 no.1
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• pp.20-26
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• 2023

Lab-on-a-disc is a circular disc shape of cartridge that can be used for blood-based liquid biopsy to diagnose an early stage of cancer. Currently, liquid biopsies are regarded as a time-consuming process, and require sophisticated skills to precisely separate cell-free DNA (cfDNA) and circulating tumor cells (CTCs) floating in the bloodstream for accurate diagnosis. However, by applying the lab-on-a-disc to liquid biopsy, the entire process can be operated automatically. To do so, the lab-on-a-disc should be designed to prevent blood leakage during the centrifugation, transport, and dilution of blood inside the lab-on-a-disc in the process of liquid biopsy. In this study, the main components of lab-on-a-disc for liquid biopsy are fabricated by injection molding for mass production, and ultrasonic welding is employed to ensure the bonding strength between the components. To guarantee accurate ultrasonic welding, the flatness of the components is optimized numerically by using the response surface methodology with four main injection molding processing parameters, including the mold & resin temperatures, the injection speed, and the packing pressure. The 27 times finite element analyses using Moldflow® reveal that the injection time and the packing pressure are the critical factors affecting the flatness of the components with an optimal set of values for all four processing parameters. To further improve the flatness of the lab-on-a-disc components for stable mass production, a quarter-disc shape of lab-on-a-disc with a radius of 75 mm is used instead of a full circular shape of the disc, and this significantly decreases the standard deviation of flatness to 30% due to the reduced overall length of the injection molded components by one-half. Moreover, it is also beneficial to use a quarter disc shape to manage the deviation of flatness under 3 sigma limits.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.4 no.2
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• pp.133-142
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• 1984

With the weld-joined compact tension specimens compared with each other, that is, transverse and lengthwise about the crack propagation direction, high and low in the input heat level, same as and lower than the base metal in the strength of weld material, the fatigue test were performed. With these data, the log-log curves between the fatigue crack propagation rate ${\frac{da}{dN}}$ and the transition range of the stress intensity factor ${\Delta}K$ ahead the crack tip were drawed. These curves were compared and estimated among each compared specimens, among each zones, that is, the base metal, the heat-affected metal and the weld-mixed metal, and between this study and the past studies. Basically, Little difference in the slope of the $da/dN-{\Delta}K$ relation was showed in all the welded directions, all the input heat levels and all the zones. But, First, to comparison with in the past studies about the base metals, it was showed that da/dN started in the much later rate, increased faster and stoped in the little faster rate. Second, it was showed that, near the time the crack's going from the heat-affected zone to the weld-mixed metal da/dN decreased a little for a while. Third, in the lengthwise weld compared with the transverse weld, in the high input heat weld compared with the low input heat weld in the case used the weld material of the same strength as the base metal, in the opposite case in the case used the one of the lower strength than the base metal, in the case used the weld material of the same strength as compared with the lower strength than the base metal beside the high input heat and the lengthwise weld, it was showed that the crack occured earlier in lower ${\Delta}K$ and later da/dN, the curves went with the same slope. Forth, in the lengthwise weld compared with the transverse weld in the low input heat weld, in the low input heat weld compared with the high input heat weld, it was showed that da/dN went with the lower level.

• Journal of Korean Society of Steel Construction
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• v.17 no.5 s.78
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• pp.637-648
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• 2005

Innovative prestressed steel plate girders were presented in this study. Hot-rolled H beams were loaded first, then relatively high-strengthsteel plates were welded on the top and bottom flanges of preloaded H beams. Finally, high prestressed plate (HiPP) girder was manufactured by simply releasing prestresses of rolled beams. To verify prestress distributions induced in this girder, the experimental study was conducted and some guidelines to manufacture these girders effectively were addressed. In addition, methods to determine the allowable bending stress of HiPP girders and to check welding stresses were addressed for design of temporary bridges. The efficiency and effectiveness of the present girder were demonstrated through design examples of temporary bridges adapting the prestress-induced girder or the plate girder of the same section without prestresses. As a result, it has been found to be possible that the span length of HiPP girders for temporary bridges is longer than that of girders without prestresses.

• Journal of Korean Society of Steel Construction
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• v.20 no.5
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• pp.645-653
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• 2008

Welded built-up square tubes are manufactured by flare welding at the center of the column width for cold-formed L-shaped four-piece plates and improved composite effect of concrete and steel by vertical inner anchor. Also, the axial resistance of concrete is increased by the thinness of the steel column, and the composite effect of concrete and steel prevents the steel column from local buckling. In this study, we introduced a manufacturing method of built-up square column steel square concrete-filled tubular column with vertical inner anchor and superior structural performance of the square stub column verified by the structural test for 15 specimens with parameters of shape of tube (built-up square tube, general steel tube), width over thickness of the steel tube (B/t=50, 58, 67) and the strength of concrete (f'c=10MPa, 50MPa).

• Journal of the Microelectronics and Packaging Society
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• v.17 no.4
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• pp.41-48
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• 2010

To improve the pot life of one-part in-house anisotropic conductive paste (ACP) formulations, 2-methyl imidazole curing accelerator powders were encapsulated with five agents. Through measuring the melting point of the five agents using DSC, it was confirmed that a encapsulation process with liquid-state agents is possible. Viscosity of ACP formulations containing the encapsulated imidazole powders was measured as a function of storage time from viscosity measurements. As a result, pot life of the formulations containing imidazole powders encapsulated with stearic acid and carnauba wax was improved, and these formulations indicated similar curing behaviors to a basic formulation containing rare imidazole. However, the bondlines made of these formulations exhibited low average shear strength values of about 37% level in comparison with the basic formulation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.7
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• pp.4398-4404
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• 2015

Stainless steel sheets are widely used as the structural material for dynamic machine structures, These kinds structures used stainless steel sheets are commonly fabricated by using the gas welding, For fatigue design of gas welded joints such as various type joint. It is necessary to obtain design information on stress distribution at the weldment as well as fatigue strength of gas welded joints. Thus in this paper, ${\Delta}P-N_f$ curves were obtained by fatigue tests. and, ${\Delta}P-N_f$ curves were rearranged in the ${\Delta}{\sigma}-N_f$ relation with the hot spot stresses at the gas welded joints. Using these results, the accelerated life test(ALT) is conducted. From the experiment results, an life prediction model is derived and factors are estimated. So it is intended to obtain the useful information for the fatigue lifetime of welded joints and data analysis by statistic reliability method, to save time and cost, and to develop optimum accelerated life prediction plans.

• Steel and Composite Structures
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• v.21 no.5
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• pp.1017-1029
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• 2016

When a welded circular hollow section (CHS) tubular joint is subjected to brace axial loading, failure position is located usually at the weld toe on the chord surface due to the weak flexural stiffness of the thin-walled chord. The failure mode is local yielding or buckling in most cases for a tubular joint subjected to axial load at the brace end. Especially when a cyclic axial load is applied, fracture failure at the weld toe may occur because both high stress concentration and welding residual stress along the brace/chord intersection cause the material in this region to become brittle. To improve the ductility as well as to increase the static strength, a tubular joint can be reinforced by increasing the chord thickness locally near the brace/chord intersection. Both experimental investigation and finite element analysis have been carried out to study the hysteretic behaviour of the reinforced tubular joint. In the experimental study, the hysteretic performance of two full-scale circular tubular T-joints subjected to cyclic load in the axial direction of the brace was investigated. The two specimens include a reinforced specimen by increasing the wall thickness of the chord locally at the brace/chord intersection and a corresponding un-reinforced specimen. The hysteretic loops are obtained from the measured load-displacement curves. Based on the hysteretic curves, it is found that the reinforced specimen is more ductile than the un-reinforced one because no fracture failure is observed after experiencing similar loading cycles. The area enclosed by the hysteretic curves of the reinforced specimen is much bigger, which shows that more energy can be dissipated by the reinforced specimen to indicate the advantage of the reinforcing method in resisting seismic action. Additionally, finite element analysis is carried out to study the effect of the thickness and the length of the reinforced chord segment on the hysteretic behaviour of CHS tubular T-joints. The optimized reinforcing method is recommended for design purposes.

• Korean Journal of Materials Research
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• v.28 no.8
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• pp.478-488
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• 2018

In this study, three kinds of steels are manufactured by varying the rolling conditions, and their microstructures are analyzed. Tensile and Charpy impact tests are performed at room temperature to investigate the correlation between microstructure and mechanical properties. In addition, heat affected zone(HAZ) specimens are fabricated through the simulation of the welding process, and the HAZ microstructure is analyzed. The Charpy impact test of the HAZ specimens is performed at $-40^{\circ}C$ to investigate the low temperature HAZ toughness. The main microstructures of steels are quasi-polygonal ferrite and pearlite with fine grains. Because coarse granular bainite forms with an increasing finish rolling temperature, the strength decreases and elongation increases. In the steel with the lowest reduction ratio, coarse granular bainite forms. In the HAZ specimens, fine acicular ferrites are the main features of the microstructure. The volume fraction of coarse bainitic ferrite and granular bainite increases with an increasing finish rolling temperature. The Charpy impact energy at $-40^{\circ}C$ decreases with an increasing volume fraction of bainitic ferrite and granular bainite. In the HAZ specimen with the lowest reduction ratio, coarse bainitic ferrite and granular bainite forms and the Charpy impact energy at $-40^{\circ}C$ is the lowest.

• Fire Science and Engineering
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• v.27 no.6
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• pp.21-25
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• 2013

Fire resistance steel, grading 490 MPa, had developed by using Thermo-mechanical control process (TMCP) and it has better performance at welding, seismic resistance than those of the ordinary structural steel, But the fire resistance performance is required to verify against the ordinary fire resistance, FR 490. Therefore this study was done to make database of mechanical properties at high temperature and to evaluate the structural stability at high temperature in terms of materials and structural member such as H-section from that of FR 490. The result of this study was that the structural stability of TMCP was lower than that of ordinary FR 490 at the range up about $700^{\circ}C$.

• Journal of Korean Society of Steel Construction
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• v.24 no.1
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• pp.59-71
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• 2012

Results of the analysis of the structural behavior of axially loaded nodes in freeform structure were not fully understood due to certain difficulties, including the application of various welding and bolting types. In this study, a node of single layered freeform structure was tested to determine its structural behavior when subjected to axial loads. The tests were classified into node ball tests to evaluate the center of the node subjected to cyclic and monotonic loading. The node part tests were also conducted to evaluate the whole node subjected to monotonic loading. The test showed that the node ball is safe with the tensile force, but the node ball needs to increase its strength with the node loaded compressive force due to the additional bending moment of the node ball's asymmetric form.